Inhibition of HIV-1 nuclear import via Schiff base formation with arylene bis(methylketone) compounds

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 21, 2002, Pages 3117-3119

  Al Abed, Yousef ^a   Dubrovsky, Larisa ^a   Ruzsicska, Bela ^a   Seepersaud, Mohindra ^a   Bukrinsky, Michael ^b  

^a North Shore LIJ Research Institute ^*  (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 CHLORO 6 METHYLPYRIMIDINE; 5 AMINOISOPHTHALIC ACID DIMETHYL ESTER; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ITI 0294; ITI 0299; ITI 0499; ITI 0599; LYSINE; PHTHALIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; SCHIFF BASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DNA SYNTHESIS INHIBITION; GENOME; HUMAN IMMUNODEFICIENCY VIRUS 1; NUCLEAR IMPORT; STRUCTURE ACTIVITY RELATION; VIRUS REPLICATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTI-HIV AGENTS; CELL NUCLEUS; CELLS, CULTURED; HIV-1; HUMANS; INDICATORS AND REAGENTS; KETONES; MACROPHAGES; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCHIFF BASES; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037020744     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00642-X     Document Type: Article

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