Role of the azinomycin naphthoate and central amide in sequence-dependent DNA alkylation and cytotoxicity of epoxide-bearing substructures

Organic Letters

Volumn 4, Issue 20, 2002, Pages 3545-3548

  Coleman, Robert S ^a   Burk, Christopher H ^a   Navarro, Antonio ^a   Brueggemeier, Robert W ^a   Diaz Cruz, Edgar S ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; AZINOMYCIN A; AZINOMYCIN B; CROSS LINKING REAGENT; DNA; EPOXIDE; GLYCOPEPTIDE; NAPHTHALENE DERIVATIVE; PEPTIDE;

ALKYLATION; ARTICLE; BREAST TUMOR; CELL CULTURE; CELL DIVISION; CHEMISTRY; DNA ADDUCT; DRUG EFFECT; GENETICS; HUMAN; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ALKYLATION; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BREAST NEOPLASMS; CELL DIVISION; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; EPOXY COMPOUNDS; GLYCOPEPTIDES; HUMANS; NAPHTHALENES; PEPTIDES; TUMOR CELLS, CULTURED;

EID: 0037015442     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0267275     Document Type: Article

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