DNA cross-linking by azinomycin B: Monte Carlo simulations in the evaluation of sequence selectivity

Journal of Medicinal Chemistry

Volumn 45, Issue 4, 2002, Pages 861-870

  Alcaro, Stefano ^a   Ortuso, Francesco ^a   Coleman, Robert S ^b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' GUANYLCYTOSYLCYTOSYL 3' TRINUCLEOTIDE; 5' GUANYLCYTOSYLTYROSYL 3' TRINUCLEOTIDE; 5' GUANYLTYROSYLCYTOSYL 3' TRINUCLEOTIDE; 5' GUANYLTYROSYLTYROSYL 3' TRINUCLEOTIDE; AZINOMYCIN B; AZIRIDINE DERIVATIVE; DNA; INTERCALATING AGENT; TRINUCLEOTIDE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BASE PAIRING; COMPUTER MODEL; CORRELATION FUNCTION; COVALENT BOND; DNA CROSS LINKING; DRUG CONFORMATION; DRUG DESIGN; DRUG DNA BINDING; DRUG POTENCY; DRUG SYNTHESIS; INTERCALATION COMPLEX; MOLECULAR INTERACTION; MONTE CARLO METHOD; PROBABILITY; RECEPTOR BINDING; SEQUENCE ANALYSIS; STEREOCHEMISTRY; TRINUCLEOTIDE REPEAT; VALIDATION PROCESS;

ALKYLATION; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; GLYCOPEPTIDES; INTERCALATING AGENTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MONTE CARLO METHOD; NAPHTHALENES; PEPTIDES;

EID: 0037075120     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm011040w     Document Type: Article

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