Identification and functional characterization of the novel isoforms of bovine norepinephrine transporter produced by alternative splicing

Brain Research

Volumn 934, Issue 2, 2002, Pages 152-156

  Kitayama, Shigeo ^a   Kumagai, Kei ^a   Morita, Katsuya ^a   Dohi, Toshihiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Nisoxetine; Norepinephrine transporter; Uptake

Indexed keywords

ISOPROTEIN; NISOXETINE; NORADRENALIN; NORADRENALIN TRANSPORTER; RADIOISOTOPE;

ADRENAL GLAND; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CATTLE; CONTROLLED STUDY; EXON; GENE CASSETTE; GENETIC CODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALTERNATIVE SPLICING; ANIMALS; CATTLE; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; COS CELLS; DNA, COMPLEMENTARY; EXONS; FLUOXETINE; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PRESYNAPTIC TERMINALS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; SYMPORTERS; SYNAPTIC TRANSMISSION;

EID: 0037012792     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)02417-4     Document Type: Article

References (18)

1. Neurotransmitter transporters: Recent progress
2. Acute regulation of norepinephrine transport; I. Protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
3. A variant of the bovine noradrenaline transporter reveals the importance of the C-terminal region for correct targeting to the membrane and functional expression
4. Single step method of RNA isolation by acid guanidium-thiocyanate-phenol-chloroform extraction
5. Advances in sodium-ion coupled biogenic amine transporters
6. Role of transmitter uptake mechanisms in synaptic neurotransmission
7. Structure, function and brain localization of neurotransmitter transporters
8. Dopamine transporter site-directed mutations differently alter substrate transport and cocaine binding
9. Cellular and molecular aspects of monoamine neurotransmitter transporters
10. Dominant negative isoform of rat norepinephrine transporter produced by alternative RNA splicing
11. Functional characterization of the splicing variants of human norepinephrine transporter
12. Effects of antidepressants on monoamine transporters
13. Cloning and expression of the bovine sodium-and chloride-dependent noradrenaline transporter
14. Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter
15. Molecular cloning and organization of the coding region of the human norepinephrine transporter gene
16. The human noradrenaline transporter gene contains multiple polyadenylation sites and two alternatively spliced C-terminal exons
17. 3H]Nisoxetine: A new radioligand for norepinephrine uptake sites in brain
18. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants