Functional characterization of the splicing variants of human norepinephrine transporter

Neuroscience Letters

Volumn 312, Issue 2, 2001, Pages 108-112

  Kitayama, Shigeo ^a   Morita, Katsuya ^a   Dohi, Toshihiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Alternative splicing; Membrane trafficking; Methamphetamine; Norepinephrine transporter

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; COCAINE; COMPLEMENTARY DNA; DESIPRAMINE; DOPAMINE; IMIPRAMINE; ISOPROTEIN; MESSENGER RNA; METHAMPHETAMINE; NISOXETINE; NOMIFENSINE; NORADRENALIN TRANSPORTER;

ANIMAL CELL; ARTICLE; CELL LINE; CELLULAR DISTRIBUTION; CERCOPITHECIDAE; DRUG BINDING; DRUG POTENCY; DRUG PROTEIN BINDING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KINETICS; NEUROBLASTOMA CELL; NEUROTRANSMITTER UPTAKE; NONHUMAN; NORADRENERGIC SYSTEM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA SPLICING; SYNAPSE;

ADRENERGIC UPTAKE INHIBITORS; ALTERNATIVE SPLICING; ANIMALS; BINDING, COMPETITIVE; CELL COMPARTMENTATION; CELL MEMBRANE; CELL NUCLEUS; COS CELLS; FLUOXETINE; HUMANS; IMMUNOHISTOCHEMISTRY; NERVOUS SYSTEM; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PROTEIN ISOFORMS; RADIOLIGAND ASSAY; SYMPORTERS; SYNAPTIC TRANSMISSION;

EID: 0035914155     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02138-3     Document Type: Article

References (16)

1. Acute regulation of norepinephrine transport; I. Protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
2. Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-pyridinium
3. A variant of the bovine noradrenaline transporter reveals the importance of the C-terminal region for correct targeting to the membrane and functional expression
4. Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters
5. Structure, function and brain localization of neurotransmitter transporters
6. Role of transmitter uptake mechanisms in synaptic neurotransmission
7. Dopamine transporter site-directed mutations differently alter substrate transport and cocaine binding
8. Dominant negative isoform of rat norepinephrine transporter produced by alternative RNA splicing
9. The dopamine transporter carboxy-terminal tail: Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain
10. Cloning and expression of the bovine sodium- and chloride-dependent noradrenaline transporter
11. Expression cloning of a cocaine- and antidepressant- sensitive human noradrenaline transporter
12. Molecular cloning and organization of the coding region of the human norepinephrine transporter gene
13. The human noradrenaline transporter gene contains multiple polyadenylation sites and two alternatively spliced C-terminal exons
14. Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast
15. 3H]Nisoxetine: A new radioligand for norepinephrine uptake sites in brain
16. Noradrenaline transport and transporter mRNA of rat chromaffin cells are controlled by dexamethasone and nerve growth factor