The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H10 synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: A model study

Experimental Gerontology

Volumn 37, Issue 2-3, 2002, Pages 341-348

  Sourlingas, Thomae G ^a   Kypreou, Katerina P ^a   Sekeri Pataryas, Kalliope E ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

Histone H4 acetylation; Linker histone H1 zero synthesis; Peripheral blood lymphocytes; Total histone synthesis; Trichostatin A

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HISTONE H1; HISTONE H4; LINK PROTEIN; MITOGENIC AGENT; PHYTOHEMAGGLUTININ; TRICHOSTATIN A;

ACETYLATION; ADULT; AGED; AGING; ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; NORMAL HUMAN; PERIPHERAL LYMPHOCYTE; PILOT STUDY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN VARIANT;

ACETYLATION; ADULT; AGED; AGED, 80 AND OVER; AGING; ENZYME INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTES; MIDDLE AGED; MODELS, BIOLOGICAL; PILOT PROJECTS;

EID: 0037012050     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(01)00201-7     Document Type: Article

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