T-lymphocyte long-term cultures have a constant histone variant pattern during aging

Experimental Gerontology

Volumn 34, Issue 1, 1999, Pages 59-67

  Sourlingas, Thomae G ^a   Steger, Marlene ^b   Grubeck Loebenstein, Beatrice ^b   Tsapali, Dimitra S ^a   Sekeri Pataryas, K E ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Aging; Histone variant composition; Long term T cell cultures

Indexed keywords

HISTONE;

ADULT; AGED; AGING; ARTICLE; CELL AGING; CONTROLLED STUDY; DIPLOIDY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; LIFESPAN; LYMPHOCYTE CULTURE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; AGED; AGING; CELLS, CULTURED; HISTONES; HUMANS; T-LYMPHOCYTES;

EID: 0033009472     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(98)00057-6     Document Type: Article

References (35)

1. Bayreuther K., Rodermman P.H., Hommel R., Dittman K., Abbiez M. Human skin fibroblasts in vitro differentiate along a terminal cell lineage. Proc. Natl. Acad. Sci. USA. 85:1988;5112-5116.
2. Bonner W.M., West M.H.P., Stedtman J.D. Two dimensional gel analysis of histones in acid extracts of nuclei, cells and tissues. Eur. J. Biochem. 109:1980;17-23.
3. Cristofalo V.J., Pignolo R.J. Replicative senescence of human fibroblast-like cells in culture. Physiol. Rev. 73:1993;617-638.
4. Dell'Orco R.T., Worthington M.I. The effects of in vitro age and culture state on histone variant synthesis in human diploid fibroblasts. J. Cell Physiol. 136:1988;168-174.
5. Dell'Orco R.T., Worthington M.I. Histone H2A variant synthesis in aging human diploid cells. J. Gerontol. 46:1991;B81-B83.
6. D'Incalci M., Allavena P., Wu R.S., Bonner W.M. H1 variant synthesis in proliferating and quiescent human cells. Eur. J. Biochem. 154:1986;273-279.
7. Doggett D.L., Rotenberg M.O., Pignolo R.J., Phillips P.D., Cristofalo V.J. Differential gene expression between young and senescent, quiescent WI-38 cells. Mech. Ageing Dev. 65:1992;239-255.
8. Giancotti V., Berlingieri M.T., Di Fiore P.P., Fusco A., Vecchio G., Crane-Robinson C. Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus. Cancer Res. 45:1985;6051-6057.
9. o in rodents. Proc. Natl. Acad. Sci. USA. 79:1982;2333-2337.
10. Goldstein S. Replicative senescence The human fibroblast comes of age . Science. 249:1990;1129-1133.
11. Grove G.N., Zweidler A. Regulation of nucleosomal core histone variant levels in differentiating murine erythroleukemia cells. Biochemistry. 23:1984;4436-4443.
12. Grubeck-Loebenstein B., Lechner H., Trieb K. Long term in vitro growth of human T cell clones Can posmitotic "senescent" cell populations be defined? Int. Arch. Allergy Immunol. 104:1994;32-39.
13. Hayflick L., Moorhead P.S. The serial cultivation of human diploid strains. Exp. Cell Res. 25:1961;585-621.
14. Jazwinski S.M., Howard B.H., Nayak R.K. Cell cycle progression, aging, and cell death. J. Gerontol. 50A:1995;B1-B8.
15. Ligthart G.J., Corberand J.X., Fournier C., Galanaud P., Hijmans W., Kennes B., Muller-Hermlink H.K., Steinmann G.G. Admission criteria for immunogerontological studies in man The senieur Protocol . Mech. Ageing Dev. 28:1984;47-55.
16. 0 is synthesized by human lymphocytic leukemia cells but not by normal lymphocytes. Blood. 70:1987;1203-1207.
17. Martin G.M. Clonal attenuation Causes and consequences . J. Gerontol. 48:1994;B171-B172.
18. McCormick A., Campisi J. Cellular aging and senescence. Cell Biol. 3:1991;230-234.
19. o accumulation and commitment to differentiation in murine erythroleukemic cells. Exp. Cell Res. 152:1984;449-458.
20. Panyim S., Chalkley R. A new histone found only in mammalian tissues with little cell division. Biochem. Biophys. Res. Commun. 37:1969;1042-1049.
21. Pereira-Smith O.M., Smith J.R. Genetic analysis of indefinite division in human cells Identification of four complementation groups . Proc. Natl. Acad. Sci. USA. 85:1988;6042-6046.
22. Perillo N.L., Walford R.L., Newman M.A., Effros R.B. Human T-lymphocytes possess a limited in vitro life span. Exp. Gerontol. 24:1989;177-187.
23. Perillo, N.L., Naeim, F., Walford, R.C., and Effros, R.B., In vitro cellular aging in T-lymphocyte cultures: Analysis of DNA content and cell size. Exp. Cell Res.207, 131-135, 1993.
24. Pignolo R.J., Rotenberg M.O., Cristofalo V.J. Alterations in contact and density-dependent arrest state in senescent WI-38 cells. In Vitro Cell. Dev. Biol. 30:1994;471-476.
25. Pina B., Suau P. Changes in histones H2A and H3 variant composition in differentiating and mature rat brain cortical neurons. Dev. Biol. 123:1987;51-58.
26. Reibenegger G., Huber L.A., Jürgens G., Schönitzer D., Werner E.R., Wachter H., Wick G., Trail K.N. Approach to define "normal aging" in man. Immune function, serum lipids, lipoproteins, and neopterin levels. Mech. Ageing Dev. 46:1987;67-82.
27. Rogakou E.P., Sekeri-Pataryas K.E. A biochemical marker for differentiation is present in an in vitro aging cell system. Biochem. Biophys. Res. Commun. 196:1993;1274-1279.
28. Rogakou, E.P., Ph.D. Thesis, University of Athens, 1996.
29. Rosenberger R.F. The initiation of senescence and its relationship to embryonic cell differentiation. Bioessays. 17:1995;257-260.
30. Seshardi T., Campisi J. Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts. Science. 247:1990;205-208.
31. Sourlingas T.G., Aleporou-Marinou V., Pataryas T.A., Sekeri-Pataryas K.E. Influence of chlorambucil, a bifunctional alkylating agent, on the histone variant biosynthesis of HEp-2 cells. Biochem. Biophys. Acta. 1092:1991;298-303.
32. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets Procedure and some applications . Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
33. Wu R.S., Bonner W.M. Separation of basal histone synthesis from S-phase histone synthesis in dividing cells. Cell. 27:1981;321-330.
34. Wu R.S., Tsai S., Bonner W.M. Pattern of histone variant synthesis can distinguish Go from G1 cells. Cell. 31:1982;367-374.
35. Wu R.S., Tsai S., Bonner W.M. Changes in histone H3 composition and synthesis pattern during lymphocyte development. Biochemistry. 22:1983;3868-3873.