Formation of a class of enzyme inhibitors (drugs), including a chiral compound, by using imprinted polymers or biomolecules as molecular-scale reaction vessels

Angewandte Chemie - International Edition

Volumn 41, Issue 23, 2002, Pages 4459-4463

  Yu, Yihua ^a   Ye, Lei ^a   Haupt, Karsten ^a   Mosbach, Klaus ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Biomimetic synthesis; Drug research; Imprinting; Inhibitors

Indexed keywords

DRUG PRODUCTS; ENZYME INHIBITION; POLYMERS;

BUILDING BLOCKS;

ENZYMES;

ENZYME INHIBITOR; KALLIKREIN; POLYMER;

ARTICLE; BINDING SITE; CHEMISTRY; CHIRALITY; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME INHIBITOR INTERACTION; HUMAN; INHIBITION KINETICS; MOLECULAR DYNAMICS; REACTION ANALYSIS; SYNTHESIS;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; KALLIKREINS; POLYMERS;

EID: 0037011220     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3773(20021202)41:23<4459::AID-ANIE4459>3.0.CO;2-2     Document Type: Article

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