Mesaconitine-induced relaxation in rat aorta: Involvement of Ca2+ influx and nitric-oxide synthase in the endothelium

European Journal of Pharmacology

Volumn 436, Issue 3, 2002, Pages 217-225

  Mitamura, Mana ^a   Horie, Syunji ^a   Sakaguchi, Masaru ^a   Someya, Akiyoshi ^a   Tsuchiya, Shizuko ^a   Van de Voorde, Johan ^b   Murayama, Toshihiko ^a   Watanabe, Kazuo ^a  

^a CHIBA UNIVERSITY   (Japan)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

(Aconitum japonicum); (Rat); Aconiti tuber; Aorta; Mesaconitine; Nitric oxide (No); Vasorelaxation

Indexed keywords

ACETYLCHOLINE; ALKALOID DERIVATIVE; ATROPINE; BENZOYLMESACONINE; CALCIUM CHLORIDE; CALCIUM ION; HEXAMETHONIUM; MESACONINE; MESACONITINE; MUSCARINIC RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; TETRODOTOXIN; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA CONSTRICTION; ARTERY DILATATION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; EXTRACELLULAR SPACE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR RING;

ACONITINE; ANIMALS; AORTA; ATROPINE; CALCIUM; CALCIUM CHLORIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HEXAMETHONIUM; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; RATS; RATS, WISTAR; TETRODOTOXIN; THAPSIGARGIN; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0037006419     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01623-5     Document Type: Article

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