Sodium bicarbonate treatment and ubiquitin gene expression in acidotic human subjects with chronic renal failure

European Journal of Clinical Investigation

Volumn 32, Issue 7, 2002, Pages 488-492

  Roberts, R G ^a,b   Redfern, C P F ^a,b   Graham, K A ^a,b   Bartlett, K ^a,c   Wilkinson, R ^a,b   Goodship, T H J ^a,b,d  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c Department of Child Health ^*  (United Kingdom)

^d ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

Chronic renal failure; Metabolic acidosis; Protein degradation; Ubiquitin

Indexed keywords

BICARBONATE; MESSENGER RNA; PROTEASOME; UBIQUITIN;

ADULT; ARTICLE; CATABOLISM; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE MODEL; FEMALE; GENE EXPRESSION; HUMAN; MALE; METABOLIC ACIDOSIS; MUSCLE BIOPSY; NORTHERN BLOTTING; PH; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; RNA EXTRACTION;

ACIDOSIS; ADULT; BIOPSY; BLOTTING, NORTHERN; COMPLEMENT C2; FEMALE; GENE EXPRESSION; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; MUSCLE, SKELETAL; RNA; SODIUM BICARBONATE; TREATMENT FAILURE; UBIQUITIN;

EID: 0036997847     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2002.01008.x     Document Type: Article

References (30)

1. Coles GA. Body composition in chronic renal failure. Q J Med 1972;41:25-47.
2. Papadoyannakis NJ, Stefanidis CJ, McGeown M. The effect of the correction of metabolic acidosis on nitrogen and potassium balance of patients with chronic renal failure. Am J Clin Nutr 1984;40:623-7.
3. Reaich D, Channon SM, Scrimgeour CM, Goodship THJ. Ammonium chloride induced acidosis increases protein breakdown and amino acid oxidation in humans. Am J Physiol 1992;263:E735-E739.
4. Reaich D, Channon SM, Scrimgeour CM, Daley SE, Wilkinson R, Goodship THJ. Correction of acidosis in humans with chronic renal failure decreases protein degradation and amino acid oxidation. Am J Physiol 1993;265:E230-E235.
5. Williams B, Layward E, Walls J. Skeletal muscle degradation and nitrogen wasting in rats with chronic metabolic acidosis. Clin Sci 1991;80:457-62.
6. May RC, Kelly RA, Mitch WE. Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism. J Clin Invest 1986;77:614-21.
7. 2+-dependent systems. Adv Mol Cell Biol 1998;27:235-66.
8. Mitch WE, Goldberg AL. Mechanisms of disease -mechanisms of muscle wasting - the role of the ubiquitin-proteasome pathway. N Engl J Med 1996;335:1897-905.
9. Mitch WE, Medina R, Grieber S, May RC, England BK, Price SR et al. Metabolic acidosis stimulates protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes. J Clin Invest 1994;93:2127-33.
10. Roberts RG, Gilmour ER, Goodship THJ. The correction of acidosis does not increase dietary protein intake in chronic renal failure patients. Am J Kidney Dis 1996;28:350-3.
11. Henriksson KG. 'Semi-open' muscle biopsy technique. A Simple Outpatient Procedure. Acta Neurol Scand 1979;59:317-23.
12. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979;18:5294-9.
13. Prentice A, Matthews CJ, Thomas EJ, Redfern CP. The expression of retinoic acid receptors in cultured human endometrial stromal cells and effects of retinoic acid. Hum Reprod 1992;7:692-700.
14. Wiborg O, Pedersen MS, Wind A, Berglund LE, Marcker KA, Vuust J. The human ubiquitin multigene family. Some genes contain multiple directly repeated ubiquitin coding sequences. EMBO J 1985;4:755-9.
15. Fujiwara T, Tanaka K, Kumatori A, Shin S, Yoshimura T, Ichihara A et al. Molecular cloning of CDNA for proteasomes (multicatalytic proteinase complexes) from rat liver. Primary structure largest component (C2). Biochemistry 1989;28:7332-40.
16. 3H1 myocytes require an interaction between glucocorticoids and acidification. Proc Natl Acad Sci USA 1996;93:1967-71.
17. Baracos VE, DeVivo C, Hoyle DH, Goldberg AL. Activation of the ATP-Ubiquitin-Proteasome Pathway in Skeletal Muscle of Cachectic Rats Bearing a Hepatoma. Am. J Physiol 1995;268:E996-1006.
18. Whelan SA, Hightower LE. Differential induction of glucose-regulated and heat shock proteins: effects of pH and sulfhydryl-reducing agents on chicken embryo cells. J Cell Physiol 1985;125:251-8.
19. Greiber S, England BK, Price SR, Medford RM, Ebb RG, Mitch WE. Na pump defects in chronic uremia cannot be attributed to changes in Na- K-ATPase MRNA or protein. Am J Physiol 1994;266:F536-F542.
20. Bailey JL, Wang X, England BK, Price RS, Ding X, Mitch WE. The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J Clin Invest 1996;97:1447-53.
21. Hochstrasser M. Ubiquitin and intracellular protein degradation. Current Opinion Cell Biol 1992;4:1024-5.
22. ++-activated, and ubiquitin-proteasome proteolytic pathways. J Clin Invest 1996;97:1610-7.
23. ++-activated, and ATP-ubiquitin-dependent proteolytic pathways in skelelal muscle from head trauma patients. Proc Natl Acad Sci USA 1996;93:2714-8.
24. Tiao G, Hobler S, Wang JJ, Meyer TA, Luchette FA, Fischer JE et al. Sepsis is associated with increased MRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. J Clin Invest 1997;99:163-8.
25. Tiao G, Fagan JM, Samuels N, James JH, Hudson K, Lieberman M et al. Sepsis stimulates nonlysosomal, energy dependent proteolysis and increases ubiquitin MRNA levels in rat skeletal muscle. J Clin Invest 1994;94:2255-64.
26. Combaret L, Taillandier D, Voisin L, Samuels SE, Boespflug-Tanguy O, Attaix D. No alteration in gene expression of components of the ubiquitin-proteasome proteolytic pathway in dystrophin-deficient muscles. FEBS Lett 1996;393:292-6.
27. Ralliere C, Tauveron I, Taillandier D, Guy L, Boiteux JP, Giraud B et al. Glucocorticoids do not regulate the expression of proteolytic genes in skeletal muscle from cushing's syndrome patients. J Clin Endocrinol Metab 1997;82:3161-4.
28. May RC, Bailey JL, Mitch WE, Masud T, England BK. Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int 1996;49:679-83.
29. Du J, Mitch WE, Wang X, Price SR. Glucocorticoids induce proteasome c3 subunit expression in L6 Muscle Cells by opposing the suppression of its transcription by NF-kappa B. J Biol Chem 2000;275:19661-6.
30. Price SR, Bailey JL, Wang XN, Jurkovitz C, England BK, Ding XY et al. muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene-transcription. J Clin Invest 1996;98:1703-8.