Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: A case report

Clinical and Experimental Obstetrics and Gynecology

Volumn 29, Issue 4, 2002, Pages 304-305

  Kontoleon, P ^a,c   Ilias, I ^a   Koutras, D A ^b   Kontogiannis, D ^a   Papapetrou, P D ^a  

^a ALEXANDRA HOSPITAL   (Greece)

^b Evgenidion Hospital   (Greece)

^c NONE   (Greece)

Author keywords

Carbimazole; Hepatotoxicity; Pregnancy; Propylthiouracil; Thyrotoxicosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBIMAZOLE; GAMMA GLUTAMYLTRANSFERASE; LIOTHYRONINE; PROPYLTHIOURACIL; THIAMAZOLE; THYROID HORMONE; THYROTROPIN; THYROXINE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE REPORT; DELIVERY; DRUG UTILIZATION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; LIVER DYSFUNCTION; LIVER TOXICITY; PREGNANCY; THYROTOXICOSIS; TREATMENT OUTCOME;

ADULT; ANTITHYROID AGENTS; CARBIMAZOLE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HEPATITIS, TOXIC; HUMANS; HYPERTHYROIDISM; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL CARE; PROPYLTHIOURACIL;

EID: 0036987780     PISSN: 03906663     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Davis L. E., Lucas M. J., Hankins G. D., Roark M. L., Cunningham F. G.: "Thyrotoxicosis complicating pregnancy". Am. J. Obstet. Gynecol., 1989, 160, 63.
2. Millar L. K., Wing D. A., Leung A. S., Koonings P. P., Montoro M. N., Mestman J. H.: "Low birth weight and preeclampsia in pregnancies complicated by hyperthyroidism". Obstet. Gynecol., 1994, 84, 946.
3. Mandel S. J., Cooper D. S.: "The use of antithyroid drugs in pregnancy and lactation". J. Clin Endocrinol. Metab., 2001, 86, 2354.
4. Marchant B., Brownlie B. E., Hart D. M., Horton P. W., Alexander W. D.: "The placental transfer of propylthiouracil, methimazole, and carbimazole". J. Clin. Endocrinol. Metab., 1977, 45, 1187.
5. Van Dijke C. P., Heydendael R. J., De Kleine M. J.: "Methimazole, carbimazole, and congenital skin defects". Ann. Intern. Med., 1987, 106, 60.
6. Diav-Citrin O., Ornoy A.: "Teratogen update: antithyroid drugs -methimazole, carbimazole, and propylthiouracil". Teratology, 2002, 65, 38.
7. Karlsson F. A., Axelsson O., Melhus H.: "Severe embryopathy and exposure to methimazole in early pregnancy". J. Clin. Endocrinol. Metab., 2002, 87, 946.
8. Papapetrou P. D., Marchant B., Gavras H., Alexander W. D.: "Biliary excretion of 35S-labelled propylthiouracil, methimazole and carbimazole in untreated and pentobarbitone pretreated rats". Biochem. Pharmacol., 1972, 21, 363.
9. Cooper D. S.: "Treatment of thyrotoxicosis". In: Braverman L. E., Utiger RD (eds.). Werner and Ingbar's The Thyroid, Philadelphia, Lippincott-Raven, 1996, 474.
10. Williams K. V., Nayak S., Becker D., Reyes J., Burmeister L. A.: "Fifty years of experience with propylthiouracil-associated hepatotoxicity: what have we learned?". J. Clin. Endocrinol. Metab., 1997, 82, 1727.
11. Arab D. M., Malatjalian D. A., Rittmaster R. S.: "Severe cholestatic jaundice in uncomplicated hyperthyroidism treated with methimazole". J. Clin. Endocrinol. Metab., 1995, 80, 1083.
12. Schwab G. P., Wetscher G. J., Vogl W., Redmond E.: "Methimazole-induced cholestatic liver injury, mimicking sclerosing cholangitis". Langenbecks Arch. Chir., 1996, 381, 225.
13. Franklyn J. A.: "The management of hyperthyroidism". New Engl. J. Med., 1994, 330, 1731.
14. Meyer-Gessner M., Benker G., Olbricht T., Windeck R., Cissewski K., Reiners C., Reinwein D.: "Nebenwirkungen der antithyreoidalen Therapie der Hyperthyreose. Eine Untersuchung an 1256 fortlaufend betreuten Patienten". Dtsch. Med. Wochenschr., 1989, 114, 166.