The brain matrix and multifocal brain damage following a single injection of ketamine in young adult rats: Conspicuous changes in old age

Perceptual and Motor Skills

Volumn 95, Issue 3 PART 1, 2002, Pages 897-900

  Persinger, M A ^a   St Pierre, L S ^b  

^a LAURENTIAN UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACEPROMAZINE; KETAMINE; LITHIUM; PILOCARPINE;

AGE; ANIMAL; ARTICLE; BRAIN; CHEMICALLY INDUCED DISORDER; CHRONIC BRAIN DISEASE; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; MALE; NERVE CELL; PATHOLOGY; RAT; SEIZURE; WISTAR RAT;

ACEPROMAZINE; AGE FACTORS; ANIMALS; BRAIN; BRAIN DAMAGE, CHRONIC; DISEASE MODELS, ANIMAL; KETAMINE; LITHIUM; MALE; NEURONS; PILOCARPINE; RATS; RATS, WISTAR; SEIZURES;

EID: 0036985773     PISSN: 00315125     EISSN: None     Source Type: Journal    
DOI: 10.2466/pms.2002.95.3.897     Document Type: Article

References (4)

1. BOYKO W. J., GALABRU, C. K., MCGEER, E. G., & MCGEER, P. L. (1979) Thalamic injections of kainic acid produce myocardial necrosis. Life Sciences, 25, 87-98.
2. PERSINGER, M. A., PEREDERY, O., DESJARDINS, D., & EASTMAN, A. (1998) Ventricular dilatation over several weeks following induction of excitotoxic (systemic lithium/pilocarpine) lesions: potential role of damage to the substantia nigra reticulata. International Journal of Neurosaence, 94, 63-74.
3. STEWART, L. S., & PERSINGER, M. A. (2001) Ketamine prevents learning impairment when administered immediately after status epilepticus onset. Epilepsy and Behavior, 2, 585-591.
4. VAILLANCOURT, L. N., & PERSINGER, M. A. (2001) Normalization of spatial learning despite brain damage in rats receiving ketamine after seizure-induction: evidence for the neuromatrix. Psychological Reports, 88, 102-110.