Ketamine Prevents Learning Impairment When Administered Immediately after Status Epilepticus Onset

Epilepsy and Behavior

Volumn 2, Issue 6, 2001, Pages 585-591

  Stewart, Lee S ^a   Persinger, Michael A ^a  

^a LAURENTIAN UNIVERSITY   (Canada)

Author keywords

Conditioned taste aversion; Fear conditioning; Ketamine; Learning; Pilocarpine; Rat; Status epilepticus

Indexed keywords

EID: 0039698147     PISSN: 15255050     EISSN: None     Source Type: Journal    
DOI: 10.1006/ebeh.2001.0272     Document Type: Article

References (30)

1. Coulter D A, DeLorenzo R J. Basic mechanisms of status epilepticus. Adv Neurol. 79:1999;725-732.
2. Krumholz A, Sung G Y, Fisher R S, Barry E, Bergey G K, Gratton L M. Complex partial status epilepticus accompanied by serious morbidity and mortality. Neurology. 45:1995;1499-1504.
3. Hort J, Brozek G, Mares P, Luagmeier M, Komarek V. Cognitive functions after pilocarpine-induced status epilepticus: changes during silent period precede appearance of spontaneous recurrent seizures. Epilepsia. 40:1999;1177-1183.
4. Kramer U, Fattal A, Nevo Y, Leitner Y, Harel S. Mental retardation subsequent to refractory partial seizures in infancy. Brain Dev. 22:2000;31-34.
5. Leite J P, Bortolotto Z A, Cavalheiro E A. Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy. Neurosci Biobehav Rev. 14:1990;511-517.
6. Persinger M A, Makarec K, Bradley J C. Characteristics of limbic seizures evoked by peripheral injections of lithium and pilocarpine. Physiol Behav. 44:1988;27-37.
7. Mello L EAM, Cavalheiro E A, Tan A M, Kupfer W R, Pretorius J K, Babb T L, Finch D M. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia. 34:1993;985-995.
8. Mello L EAM, Covolan L. Spontaneous seizures preferentially injure interneurons in the pilocarpine model of chronic spontaneous seizures. Epilepsy Res. 26:1996;123-129.
9. Arida R M, Scorza F A, de Araujo Peres C, Cavalheiro E A. The course of untreated seizures in the pilocarpine model of epilepsy. Epilepsy Res. 34:1999;99-107.
10. Persinger M A, Bureau Y RJ, Kostakos M, Peredery O, Falter H. Behaviors of rats with insidious, multifocal brain damage induced by seizures following single peripheral injections of lithium and pilocarpine. Physiol Behav. 53:1993;849-866.
11. Persinger M A, Bureau Y RJ, Peredery O. Dissociation between conditioned taste aversion and radial maze learning following seizure-induced multifocal brain damage: quantitative tests of serial vs. parallel circuit models of memory. Physiol Behav. 56:1994;225-235.
12. Vaillancourt L N, Persinger M A. Normalization of spatial learning despite brain damage in rats receiving ketamine after seizure-induction: evidence for the neuromatrix. Psychol Rep. 88:2001;102-110.
13. Santi, S, A, Cook, L, L, Persinger, M, A, O'Connor, R, P, Normal spatial memory following postseizure treatment with ketamine: selective damage attenuates memory deficits in brain-damaged rodents, Int J Neurosci, in press.
14. Borris D J, Bertram E H, Kapur J. Ketamine controls prolonged status epilepticus. Epilepsy Res. 42:2000;117-122.
15. Fujikawa D G. Neuroprotective effect of ketamine administered after status epilepticus onset. Epilepsia. 36:1995;186-195.
16. Garcia J, Riley A L. Conditioned taste aversions. Greenburg G, Haraway M M. Comparative psychology: a handbook. 1998;Garland, New York.
17. Bolles R C. Species-specific defensive reactions and avoidance learning. Psychol Rev. 77:1970;32-48.
18. Harrigan T, Bureau Y RJ, Persinger M A, Parker G H. Prevention of sudden cardiac death by the atypical neuroleptic acepromazine following status epilepticus in rats. Life Sci. 54:1994;PL457-62.
19. Racine R J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol. 32:1972;281-284.
20. O'Callaghan J P, Holtzman S G. Quantification of the analgesic activity of narcotic antagonist by a modified hotplate procedure. J Pharmacol Exp Ther. 192:1975;495-505.
21. Stewart L S, Persinger M A. Pretraining exposure to physiologically patterned electromagnetic stimulation attenuates fear-conditioned analgesia. Int J Neurosci. 100:1999;91-98.
22. Maren S, Anagnostaras S G, Fanselow M S. The startled seahorse: is the hippocampus necessary for contextual fear conditioning? Trends, Cogn Sci. 2:1998;39-42.
23. Venugopal M, Persinger M A. Conditioned taste aversion is reduced in rats with a history of lithium/pilocarpine-induced limbic seizures. Neurosci Lett. 90:1988;177-180.
24. Sakai N, Yamamoto T. Possible routes of visceral information in the rat brain in formation of conditioned taste aversion. Neurosci Res. 35:1999;53-61.
25. Peredery O, Persinger M A, Parker G, Mastrosov L. Temporal changes in neuronal dropout following inductions of lithium/pilocarpine seizures in the rat. Brain Res. 881:2000;9-17.
26. Fox R J, Sorenson C A. Bilateral lesions of the amygdala attenuate analgesia induced by diverse environmental challenges. Brain Res. 648:1994;215-221.
27. Goldstein L E, Rasmussen A M, Bunney B S, Roth R H. Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat. J Neurosci. 16:1996;4787-4798.
28. Fanselow M S, LeDoux J E. Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron. 23:1999;229-232.
29. Mazarati A M, Wasterlain C G. N-Methyl-D-aspartate antagonists abolish the maintenance phase of self-sustaining status epilepticus in rat. Neurosci Lett. 265:1999;187-190.
30. Williamson J M, Lothman E W. The effect of MK-801 on kindled seizures: implications for use and limitations as an antiepileptic drug. Ann Neurol. 26:1989;85-90.