Increased angiotensin II AT1 receptor expression in paraventricular nucleus and hypothalamic-pituitary-adrenal axis stimulation in AT2 receptor gene disrupted mice

Neuroendocrinology

Volumn 76, Issue 3, 2002, Pages 137-147

  Armando, Inés ^a   Terrón, José A ^a   Falcón Neri, Alicia ^a   Takeshi, Ito ^a   Häuser, Walter ^a   Inagami, Tadashi ^b   Saavedra, Juan M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Adrenal gland; Adrenal steroids; Angiotensin receptors; Catecholamines; Corticotropin; Paraventricular nucleus; Renin angiotensin system; Stress

Indexed keywords

ADRENALIN; ALDOSTERONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; CANDESARTAN; CATECHOLAMINE; CORTICOSTEROID; CORTICOSTERONE; CORTICOTROPIN; DOPAMINE; HYPOPHYSIS HORMONE; MESSENGER RNA; NORADRENALIN; TYROSINE 3 MONOOXYGENASE;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; FEMALE; GENE DISRUPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOIMMUNOASSAY; RECEPTOR BINDING; RECEPTOR GENE; STRESS; THALAMUS MIDLINE NUCLEUS; TISSUE DISTRIBUTION;

ADRENAL CORTEX HORMONES; ADRENAL GLANDS; ANIMALS; BENZIMIDAZOLES; CATECHOLAMINES; FEMALE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; HYPOTHALAMUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PITUITARY-ADRENAL SYSTEM; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; RNA, MESSENGER; TETRAZOLES; TYROSINE 3-MONOOXYGENASE;

EID: 0036979253     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000064525     Document Type: Article

References (47)

1. Saavedra JM: Brain and pituitary angiotensin. Endocr Rev 1992;13:329-380.
2. Phillips MI, Sumners C: Angiotensin II in central nervous system physiology. Reg Peptides 1998;78:1-11.
3. Fitzsimons JT: Angiotensin, thirst, and sodium appetite. Physiol Rev 1998;78:583-686.
4. Timmermans PBMWM, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, Lee RJ, Wexler RR, Saye JAM, Smith RD: Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993;45:205-251.
5. Inagami T, Guo DF, Kitami Y: Molecular biology of angiotensin II receptors: An overview. J Hypertens Suppl 1994;12:S83-S94.
6. Matsusaka T, Ichikawa I: Biological functions of angiotensin and its receptors. Annu Rev Physiol 1997;59:395-412.
7. 2 angiotensin II receptor subtype gene expression in rat brain. Neuroreport 1995; 6:2549-2552.
8. 2 receptor: Fact, fancy and fantasy. Regul Pept 1999;81: 11-24.
9. Saavedra JM: 1999 Emerging features of brain angiotensin receptors. Regul Pept 1999;85:31-45.
10. Inagami T, Eguchi S, Numaguchi K, Motley ED, Tang H, Matsumoto T, Yamakawa T: Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases. J Am Soc Nephrol 1999;10:S57-S61.
11. 2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transfer. Proc Natl Acad Sci USA 1995;92:10663-10667.
12. Hein L, Barsh GS, Pratt RE, Dzau VJ, Kobilka BK: Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice. Nature 1995;377:744-747.
13. Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Niimura F, Ichikawa I, Hogan BLM, Inagami T: Effects on blood pressure and explorative behaviour of mice lacking angiotensin II type-2 receptor. Nature 1995; 377:748-750.
14. Watanabe T, Hashimoto M, Okuyama S, Inagami T, Nakamura S: Effects of targeted disruption of the mouse angiotensin II type 2 receptor gene on stress-induced hyperthermia. J Physiol 1999;515:881-885.
15. Okuyama S, Sakagawa T, Chaki S, Imagawa Y, Ichiki T, Inagami T: Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor. Brain Res 1999;821:150-159.
16. 2 receptor gene-disrupted mice. Am J Physiol 2001;280:F71-F78.
17. Saavedra JM, Armando I, Terrón JA, Falcón-Neri A, Jöhren O, Häuser W, Inagami T: Increased AT1 receptors in adrenal gland of AT2 receptor gene-disrupted mice. Regul Pept 2001;102:41-47.
18. Tanaka M, Tsuchida S, Imai T, Fujii N, Miyazaki H, Ichiki T, Naruse M, Inagami T: Vascular response to angiotensin II is exaggerated through an upregulation of AT1 receptors in AT2 knockout mice. Biochem Biophys Res Commun 1999;258:194-198.
19. Armando I, Nowicki S, Aguirre J, Barontini M: A decreased tubular uptake of dopa results in defective renal dopamine production in aged rats. Am J Physiol 1995;268:F1087-1092.
20. Häuser W, Jöhren O, Saavedra, J.M: Characterization and distribution of angiotensin II receptor subtypes in the mouse brain. Eur J Pharm 1998;348:101-114.
21. 14C-plastic standards for quantitative autoradiography using LKB Ultrofilm or Amersham Hyperfilm. Neurosci Lett 1991;121:211-214.
22. Iwai N, Yamano Y, Chaki S, Konishi F, Bardhan S, Tibhetts C, Sasaki K, Hasegawa M, Matsuda, Y, Inagami T: Rat angiotensin II receptor: cDNA sequence and regulation of the gene expression. Biochim Biophys Res Commun 1991;177:299-304.
23. Sasamura H, Hein L, Krieger JE, Pratt RE, Kobilka BK, Dzau VJ: Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome. Biochem Biophys Res Commun 1992;185: 253-259.
24. Wisden W, Morris BJ: In situ hybridization with synthetic oligonucleotide probes; in Wisden W, Morris BJ (eds): In situ Hybridization Protocols for the Brain. San Diego, Academic Press, 1994, pp 9-34.
25. Grima B, Lamouroux A, Blanot F, Biguet NF, Mallet J: Complete coding sequence of rat tyrosine hydroxylase mRNA. Proc Natl Acad Sci USA 1985;82:617-621.
26. Swanson LW, Sawchenko PE: Paraventricular nucleus: A site for the integration of neuroendocrine and autonomic mechanisms. Prog Neuroendocrinol 1980;31:410-417.
27. Castrén E, Saavedra JM: Repeated stress increases the density of angiotensin II binding sites in the rat paraventricular nucleus and subfornical organ. Endocrinology 1988;122:370-372.
28. Aguilera G, Kiss A, Luo X: Increased expression of type 1 angiotensin II receptors in the hypothalamic paraventricular nucleus following stress and glucocorticoid administration. J Neuroendocrinol 1995;7:775-783.
29. 2 receptors. Neuroendocrinology 2002;75:227-240.
30. 1 receptor antagonist decreases the hypothalamic-pituitary-adrenal response to stress. Endocrinology 2001; 142:3880-3889.
31. Sumitomo T, Suda T, Nakano Y, Tozawa F, Yamada M, Demura H: Angiotensin II increases the corticotropin-releasing factor messenger ribonucleic acid level in the rat hypothalamus. Endocrinology 1991;128:2248-2252.
32. Aguilera G, Young WS, Kiss A, Bathia A: Direct regulation of hypothalamic corticotropin-releasing-hormone neurons by angiotensin II. Neuroendocrinology 1995;61:437-444.
33. Jezova D, Ochedalski T, Kiss A, Aguilera G: Brain angiotensin II modulates sympatho-adrenal and hypothalamic pituitary adrenocortical activation during stress. J Neuroendocrinol 1998;10:67-72.
34. Livett BG, Marley PD, Wan DC, Zhou XF: Peptide regulation of adrenal medullary function. J Neurol Transm Suppl 1990;9:77-89.
35. Wong PC, Hart SD, Zaspel AM, Chiu AT, Ardecky J, Smith, RD, Timmermans PBMWM: Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands. Dup 753 (AII-1) and PD 123177 (AII-2). J Pharm Exp Ther 1990;255:584-592.
36. 125I]CGP 42112. Brain Res 1995: 677:29-38.
37. Israel A, Strömberg C, Tsutsumi K, Garrido MR, Torres M, Saavedra JM: Angiotensin II receptor subtypes and phosphoinositide hydrolysis in rat adrenal medulla. Brain Res Bull 1995;38:441-446.
38. Nishimura Y, Ito T, Hoe K-L, Saavedra JM: Chronic peripheral administration of the angiotensin II AT1 receptor antagonist candesartan blocks brain AT1 receptors. Brain Res 2000;871:29-38.
39. Balla T, Baukal AJ, Eng, S, Catt, KJ: Angiotensin II receptor subtypes and biological responses in the adrenal cortex and medulla. Mol Pharm 1991;40:401-406.
40. Belloni AS, Andreis PG, Macchi V, Gottardo G, Malendowicz LK, Nussdorfer GG: Distribution and functional significance of angiotensin-II AT1 and AT2 receptor subtypes in the rat adrenal gland. Endocr Res 1998;24:1-15.
41. +-induced aldosterone secretion from human adrenocortical NCI-H295 cells. Hypertension 1999;33:1025-1030.
42. Wada T, Inada Y, Sanada T, Ojima M, Shibouta Y, Noda M, Nishikawa K: Effect of an Angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone. Eur J Pharmacol 1994;253:27-34.
43. Vinson GP. The adrenal renin/angiotensin system; in Mukhopadhyay AK, Raizada MK (eds): Tissue Renin-Angiotensin Systems. New York, Plenum Press, 1995, pp 237-251.
44. Naruse M, Tanabe A, Sugaya T, Naruse K, Yoshimoto T, Seki T, Imaki T, Demura R, Murakami K, Demura H: Differential roles of angiotensin receptor subtypes in adrenocortical function in mice. Life Sci 1998;63:1593-1598.
45. 1 receptor by angiotensin II in the rat adrenal gland. Eur J Pharm 1998; 350:129-139.
46. Masaki H, Kurihara T, Yamaki A, Inomata N, Nozawa Y, Mori Y, Murasawa S, Kizima K, Maruyama K, Horiuchi M, Dzau VJ, Takahashi H, Iwasaka T, Inada M, Matsubara H: Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. J Clin Invest 1998;101:527-535.
47. Gerband CH, Zhu M, Lu D, Reagan LP, Fluharty SJ, Posner P, Raizada MK, Sumners C: Functional interactions between neuronal AT1 and AT2 receptors. Endocrinology 1997;138: 2195-2198.