-
1
-
-
0031852204
-
Hypothesis: Multiple sclerosis is a type I interferon deficiency syndrome
-
BROD, S.A. (1998). Hypothesis: multiple sclerosis is a type I interferon deficiency syndrome. Proc. Soc. Exp. Biol. Med. 218, 278-283.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.218
, pp. 278-283
-
-
Brod, S.A.1
-
2
-
-
0030824070
-
Gut response. Therapy with ingested immunomodulatory proteins
-
BROD, S.A. (1997). Gut response. Therapy with ingested immunomodulatory proteins. Arch. Neurol. 54, 1300-1302.
-
(1997)
Arch. Neurol.
, vol.54
, pp. 1300-1302
-
-
Brod, S.A.1
-
3
-
-
0032818247
-
Immunomodulation and therapeutic effects of the oral use of interferon-alpha: Mechanism of action
-
TOMPKINS, W.A. (1999). Immunomodulation and therapeutic effects of the oral use of interferon-alpha: mechanism of action. J. Interferon Cytokine Res. 19, 817-828.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 817-828
-
-
Tompkins, W.A.1
-
4
-
-
0025185153
-
Is interferon effective after oral administration?
-
BOCCI, V. (1990). Is interferon effective after oral administration? J. Biol. Reg. Homeostasis Agents 4, 81-83.
-
(1990)
J. Biol. Reg. Homeostasis Agents
, vol.4
, pp. 81-83
-
-
Bocci, V.1
-
5
-
-
0000383435
-
Multiple sclerosis
-
S. Appel (ed.) St. Louis: Mosby - Year Book, Inc.
-
WOLINSKY, J. (1993). Multiple sclerosis. In: Current Neurology. S. Appel (ed.) St. Louis: Mosby - Year Book, Inc. pp. 167-207.
-
(1993)
Current Neurology
, pp. 167-207
-
-
Wolinsky, J.1
-
7
-
-
0018305482
-
Suppressor cell function in multiple sclerosis: Correlation with clinical disease activity
-
ANTEL, J.P., ARNASON, B.G.W., and MEDOF, M.E. (1979). Suppressor cell function in multiple sclerosis: correlation with clinical disease activity. Ann. Neurol. 5, 338-342.
-
(1979)
Ann. Neurol.
, vol.5
, pp. 338-342
-
-
Antel, J.P.1
Arnason, B.G.W.2
Medof, M.E.3
-
8
-
-
0027418515
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
-
THE IFNB MULTIPLE SCLEROSIS GROUP. (1993). Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43, 655-661.
-
(1993)
Neurology
, vol.43
, pp. 655-661
-
-
-
9
-
-
0008678962
-
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
-
The Multiple Sclerosis Collaborative Research Group (MSCRG)
-
JACOBS, L., COOKFAIR, D., RUDICK, R., HERNDON, R., RICHERT, J., SALAZAR, A., FISCHER, J., GRANGER, C., SIMON, J., GOODKIN, D., GRANGER, C., SIMON, J., ALAM, J., BARTOSZAK, D., BOURDETTE, D., BRAIMAN, J., BROWN-SCHEIDLE, C., COATS, M., COHAN, S., DOUGHERTY, D., KINKEL, R., MASS, M., MUNSCHAUER, F., PRIORE, R., PULLICINO, P., SCHEROKMAN, B., and WHITHAM, R. (1994). Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann. Neurol. 39, 285-294.
-
(1994)
Ann. Neurol.
, vol.39
, pp. 285-294
-
-
Jacobs, L.1
Cookfair, D.2
Rudick, R.3
Herndon, R.4
Richert, J.5
Salazar, A.6
Fischer, J.7
Granger, C.8
Simon, J.9
Goodkin, D.10
Granger, C.11
Simon, J.12
Alam, J.13
Bartoszak, D.14
Bourdette, D.15
Braiman, J.16
Brown-Scheidle, C.17
Coats, M.18
Cohan, S.19
Dougherty, D.20
Kinkel, R.21
Mass, M.22
Munschauer, F.23
Priore, R.24
Pullicino, P.25
Scherokman, B.26
Whitham, R.27
more..
-
10
-
-
0037154192
-
Disease modifying therapies in multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines
-
GOODIN, D.S., FROHMAN, E.M., GARMANY, G.P., Jr., HALPER, J., LIKOSKY, W.H., LUBLIN, F.D., SILBERBERG, D.H., STUART, W.H., and VAN DEN NOORT, S. (2002). Disease modifying therapies in multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice Guidelines. Neurology 58, 169-178.
-
(2002)
Neurology
, vol.58
, pp. 169-178
-
-
Goodin, D.S.1
Frohman, E.M.2
Garmany G.P., Jr.3
Halper, J.4
Likosky, W.H.5
Lublin, F.D.6
Silberberg, D.H.7
Stuart, W.H.8
Van Den Noort, S.9
-
11
-
-
0033596756
-
Interferon-alpha2a reduces MRI disease activity in relapsing-remitting multiple sclerosis
-
Norwegian Study Group on Interferon-alpha in Multiple Sclerosis
-
MYHR, K.M., RIISE, T., GREEN LILLEAS, F.E., BEISKE, T.G., CELIUS, E.G., EDLAND, A., JENSEN, D., LARSEN, J.P., NILSEN, R., NORTVEDT, M.W., SMIEVOLL, A.I., VEDELER, C., and HYLAND, H.I. (1999). Interferon-alpha2a reduces MRI disease activity in relapsing-remitting multiple sclerosis. Norwegian Study Group on Interferon-alpha in Multiple Sclerosis. Neurology 52, 1049-1056.
-
(1999)
Neurology
, vol.52
, pp. 1049-1056
-
-
Myhr, K.M.1
Riise, T.2
Green Lilleas, F.E.3
Beiske, T.G.4
Celius, E.G.5
Edland, A.6
Jensen, D.7
Larsen, J.P.8
Nilsen, R.9
Nortvedt, M.W.10
Smievoll, A.I.11
Vedeler, C.12
Hyland, H.I.13
-
12
-
-
0028348216
-
Chronic systemic high-dose recombinant interferon alfa-2a reduces exacerbation rate, MRI signs of disease activity, and lymphocyte interferon gamma production in relapsing-remitting multiple sclerosis
-
DURELLI, L., BONGIOANNI, M.R., CAVALLO, R., FERRERO, B., FERRI, R., FERRIO, M.F., BRADAC, G.B., RIVA, A., VAI, S., GEUNA, M., et al. (1994). Chronic systemic high-dose recombinant interferon alfa-2a reduces exacerbation rate, MRI signs of disease activity, and lymphocyte interferon gamma production in relapsing-remitting multiple sclerosis. Neurology 44, 406-413.
-
(1994)
Neurology
, vol.44
, pp. 406-413
-
-
Durelli, L.1
Bongioanni, M.R.2
Cavallo, R.3
Ferrero, B.4
Ferri, R.5
Ferrio, M.F.6
Bradac, G.B.7
Riva, A.8
Vai, S.9
Geuna, M.10
-
13
-
-
0033472729
-
Effect of interferon-beta1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: Results of a European multicenter, randomized, double-blind, placebo-controlled trial
-
European Study Group on Interferon-beta1b in secondary progressive multiple sclerosis
-
MILLER, D.H., MOLYNEUX, P.D., BARKER, G.J., MACMANUS, D.G., MOSELEY, I.F., and WAGNER, K. (1999). Effect of interferon-beta1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: results of a European multicenter, randomized, double-blind, placebo-controlled trial. European Study Group on Interferon-beta1b in secondary progressive multiple sclerosis. Ann. Neurol. 46, 850-859.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 850-859
-
-
Miller, D.H.1
Molyneux, P.D.2
Barker, G.J.3
Macmanus, D.G.4
Moseley, I.F.5
Wagner, K.6
-
14
-
-
0030072651
-
Clinical and magnetic resonance imaging predictors of disability in primary and secondary progressive multiple sclerosis
-
LOSSEFF, N.A., KINGSLEY, D.P., McDONALD, W.I., MILLER, D.H., and THOMPSON, A.J. (1996). Clinical and magnetic resonance imaging predictors of disability in primary and secondary progressive multiple sclerosis. Mult. Scler. 1, 218-222.
-
(1996)
Mult. Scler.
, vol.1
, pp. 218-222
-
-
Losseff, N.A.1
Kingsley, D.P.2
McDonald, W.I.3
Miller, D.H.4
Thompson, A.J.5
-
15
-
-
0029161628
-
Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial
-
THE IFNB MULTIPLE SCLEROSIS STUDY GROUP and THE UNIVERSITY OF BRITISH COLUMBIA MS/MRI ANALYSIS GROUP. (1995). Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. Neurology 45, 1277-1285.
-
(1995)
Neurology
, vol.45
, pp. 1277-1285
-
-
-
16
-
-
0005489101
-
Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years
-
THE IFNB MULTIPLE SCLEROSIS STUDY GROUP and THE UNIVERSITY OF BRITISH COLUMBIA MS/MRI ANALYSIS GROUP. (1996). Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 47, 889-894.
-
(1996)
Neurology
, vol.47
, pp. 889-894
-
-
-
17
-
-
0029950889
-
Interferon-beta 1b treatment decreases tumor necrosis factor-alpha and increases interleukin-6 production in multiple sclerosis
-
BROD, S.A., MARSHALL, G.D., Jr., HENNINGER, E.M., SRIRAM, S., KHAN, M., and WOLINSKY, J.S. (1996). Interferon-beta 1b treatment decreases tumor necrosis factor-alpha and increases interleukin-6 production in multiple sclerosis. Neurology 46, 1633-1638.
-
(1996)
Neurology
, vol.46
, pp. 1633-1638
-
-
Brod, S.A.1
Marshall G.D., Jr.2
Henninger, E.M.3
Sriram, S.4
Khan, M.5
Wolinsky, J.S.6
-
18
-
-
0022475906
-
The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: A 25-year review of deaths in patients under 20 years of age in the United Kingdom
-
FOULIS, A.K., LIDDLE, C.N., FARQUHARSON, M.A., RICHMOND, J.A., and WEIR, R.S. (1986). The histopathology of the pancreas in type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia 29, 267-274.
-
(1986)
Diabetologia
, vol.29
, pp. 267-274
-
-
Foulis, A.K.1
Liddle, C.N.2
Farquharson, M.A.3
Richmond, J.A.4
Weir, R.S.5
-
19
-
-
0023735943
-
Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus
-
SILVERSTEIN, J., MACLAREN, N., RILEY, W., SPILLAR, R., RADJENOVIC, D., and JOHNSON, S. (1988). Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus. N. Engl. J. Med. 319, 599-604.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 599-604
-
-
Silverstein, J.1
Maclaren, N.2
Riley, W.3
Spillar, R.4
Radjenovic, D.5
Johnson, S.6
-
20
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
THE DIABETES CONTROL AND COMPLICATIONS TRIAL RESEARCH GROUP. (1993). The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329, 977-986.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 977-986
-
-
-
21
-
-
0024504171
-
A randomized trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus
-
SHAH, S., MALONE, J., and SIMPSON, N. (1989). A randomized trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus. N. Engl. J. Med. 320, 550-554.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 550-554
-
-
Shah, S.1
Malone, J.2
Simpson, N.3
-
22
-
-
0023709376
-
Cyclosporin-induced remission of IDDM after early intervention. Association of 1 yr of cyclosporin treatment with enhanced insulin secretion
-
CANADIAN-EUROPEAN RANDOMIZED CONTROL TRIAL GROUP. (1988). Cyclosporin-induced remission of IDDM after early intervention. Association of 1 yr of cyclosporin treatment with enhanced insulin secretion. Diabetes 37, 1574-1582.
-
(1988)
Diabetes
, vol.37
, pp. 1574-1582
-
-
-
23
-
-
0022619110
-
Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial
-
FEUTREN, G., PAPOZ, L., ASSAN, R., VIALETTES, B., KARSENTY, G., VEXIAU, P., DU ROSTU, H., RODIER, M., SIRMAI, J., and LALLEMAND, A. (1986). Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial. Lancet 2, 119-124.
-
(1986)
Lancet
, vol.2
, pp. 119-124
-
-
Feutren, G.1
Papoz, L.2
Assan, R.3
Vialettes, B.4
Karsenty, G.5
Vexiau, P.6
Du Rostu, H.7
Rodier, M.8
Sirmai, J.9
Lallemand, A.10
-
24
-
-
0025049497
-
Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin
-
BOUGNERES, P., LANDAIS, P., BOISSON, C., CAREL, J., FRAMENT, N., BOITARD, C., CHAUSSAIN, J., and BACH, J. (1990). Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin. Diabetes 39, 1264-1272.
-
(1990)
Diabetes
, vol.39
, pp. 1264-1272
-
-
Bougneres, P.1
Landais, P.2
Boisson, C.3
Carel, J.4
Frament, N.5
Boitard, C.6
Chaussain, J.7
Bach, J.8
-
25
-
-
0024813410
-
Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes
-
COOK, J., HUDSON, I., HARRISON, L., DEAN, B., COLMAN, P., WERTHER, G., WARNE, G., and COURT, J. (1989). Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes. Diabetes 38, 779-783.
-
(1989)
Diabetes
, vol.38
, pp. 779-783
-
-
Cook, J.1
Hudson, I.2
Harrison, L.3
Dean, B.4
Colman, P.5
Werther, G.6
Warne, G.7
Court, J.8
-
26
-
-
0025294001
-
A trial of nicotinamide in newly diagnosed patients with type 1 (insulin-dependent) diabetes mellitus
-
CHASE, H., BUTLER-SIMON, N., GARG, S., McDUFFIE, M., HOOPS, S., and O'BRIEN, D. (1990). A trial of nicotinamide in newly diagnosed patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia 33, 444-446.
-
(1990)
Diabetologia
, vol.33
, pp. 444-446
-
-
Chase, H.1
Butler-Simon, N.2
Garg, S.3
McDuffie, M.4
Hoops, S.5
O'Brien, D.6
-
27
-
-
0026543134
-
Double-blind randomized trial of nicotinamide on early-onset diabetes
-
LEWIS, C., CANAFAX, D., SPRAFKA, J., and BARBOSA, J. (1992). Double-blind randomized trial of nicotinamide on early-onset diabetes. Diabetes Care 15, 121-123.
-
(1992)
Diabetes Care
, vol.15
, pp. 121-123
-
-
Lewis, C.1
Canafax, D.2
Sprafka, J.3
Barbosa, J.4
-
28
-
-
0029078738
-
Double-blind trial of nicotinamide in recent-onset IDDM (the IMDIAB III study)
-
POZZILLI, P., VISALLI, N., SIGNORE, A., BARONI, M., BUZZETTI, R., CAVALLO, M., BOCCUNI, M., FAVA, D., GRAGNOLI, C., ANDREANI, D., et al. (1995). Double-blind trial of nicotinamide in recent-onset IDDM (the IMDIAB III study). Diabetologia 38, 848-852.
-
(1995)
Diabetologia
, vol.38
, pp. 848-852
-
-
Pozzilli, P.1
Visalli, N.2
Signore, A.3
Baroni, M.4
Buzzetti, R.5
Cavallo, M.6
Boccuni, M.7
Fava, D.8
Gragnoli, C.9
Andreani, D.10
-
29
-
-
0019762336
-
Adult and juvenile rheumatoid arthritis: Current epidemiologic concepts
-
HOCHBERG, M.C. (1981). Adult and juvenile rheumatoid arthritis: current epidemiologic concepts. Epidemiol. Rev. 3, 27-44.
-
(1981)
Epidemiol. Rev.
, vol.3
, pp. 27-44
-
-
Hochberg, M.C.1
-
30
-
-
0023179033
-
Long-term outcome of treating rheumatoid arthritis: Results after 20 years
-
SCOTT, D.L., SYMMONS, D.P., COULTON, B.L., and POPERT, A.J. (1987). Long-term outcome of treating rheumatoid arthritis: results after 20 years. Lancet 1, 1108-1111.
-
(1987)
Lancet
, vol.1
, pp. 1108-1111
-
-
Scott, D.L.1
Symmons, D.P.2
Coulton, B.L.3
Popert, A.J.4
-
31
-
-
0028105830
-
Prediction of long-term mortality in patients with rheumatoid arthritis according to simple questionnaire and joint count, measures
-
PINCUS, T., BROOKS, R.H., and CALLAHAN, L.F. (1994). Prediction of long-term mortality in patients with rheumatoid arthritis according to simple questionnaire and joint count, measures. Ann. Intern. Med. 120, 26-34.
-
(1994)
Ann. Intern. Med.
, vol.120
, pp. 26-34
-
-
Pincus, T.1
Brooks, R.H.2
Callahan, L.F.3
-
32
-
-
0028328810
-
The mortality of rheumatoid arthritis
-
WOLFE, F., MITCHELL, D.M., SIBLEY, J.T., FRIES, J.F., BLOCH, D.A., WILLIAMS, C.A., SPITZ, P.W., HAGA, M., KLEINHEKSEL, S.M., and CATHEY, M.A. (1994). The mortality of rheumatoid arthritis. Arthritis Rheum. 37, 481-494.
-
(1994)
Arthritis Rheum
, vol.37
, pp. 481-494
-
-
Wolfe, F.1
Mitchell, D.M.2
Sibley, J.T.3
Fries, J.F.4
Bloch, D.A.5
Williams, C.A.6
Spitz, P.W.7
Haga, M.8
Kleinheksel, S.M.9
Cathey, M.A.10
-
33
-
-
17144445094
-
Treatment of early rheumatoid arthritis with minocycline or placebo: Results of a randomized, double-blind, placebo-controlled trial
-
O'DELL, J.R., HAIRE, C.E., PALMER, W., DRYMALSKI, W., WEES, S., BLAKELY, K., CHURCHILL, M., ECKHOFF, P.J., WEAVER, A., DOUD, D., ERIKSON, N., DIETZ, F., OLSON, R., MALOLEY, P., KLASSEN, L.W., and MOORE, G.F. (1997). Treatment of early rheumatoid arthritis with minocycline or placebo: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 40, 842-848.
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 842-848
-
-
O'Dell, J.R.1
Haire, C.E.2
Palmer, W.3
Drymalski, W.4
Wees, S.5
Blakely, K.6
Churchill, M.7
Eckhoff, P.J.8
Weaver, A.9
Doud, D.10
Erikson, N.11
Dietz, F.12
Olson, R.13
Maloley, P.14
Klassen, L.W.15
Moore, G.F.16
-
34
-
-
0025080342
-
Termination of slow acting antirheumatic therapy in rheumatoid arthritis: A 14-year prospective evaluation of 1017 consecutive starts
-
WOLFE, F., HAWLEY, D.J., and CATHEY, M.A. (1990). Termination of slow acting antirheumatic therapy in rheumatoid arthritis: a 14-year prospective evaluation of 1017 consecutive starts. J. Rheumatol. 17, 994-1002.
-
(1990)
J. Rheumatol.
, vol.17
, pp. 994-1002
-
-
Wolfe, F.1
Hawley, D.J.2
Cathey, M.A.3
-
35
-
-
0026766850
-
Life table analysis of 879 treatment episodes with slow acting antirheumatic drugs in community rheumatology practice
-
published erratum appears in J. Rheumatol. 1992;19:1998
-
MORAND, E.F., McCLOUD, P.I., and LITTLEJOHN, G.O. (1992). Life table analysis of 879 treatment episodes with slow acting antirheumatic drugs in community rheumatology practice [published erratum appears in J. Rheumatol. 1992;19:1998]. J. Rheumatol. 19, 704-708.
-
(1992)
J. Rheumatol.
, vol.19
, pp. 704-708
-
-
Morand, E.F.1
McCloud, P.I.2
Littlejohn, G.O.3
-
36
-
-
0030000725
-
Guidelines for monitoring drug therapy in rheumatoid arthritis
-
AMERICAN COLLEGE OF RHEUMATOLOGY AD HOC COMMITTEE ON CLINICAL GUIDELINES. (1996). Guidelines for monitoring drug therapy in rheumatoid arthritis. Arthritis Rheum. 39, 723-731.
-
(1996)
Arthritis Rheum.
, vol.39
, pp. 723-731
-
-
-
37
-
-
0029869174
-
The effectiveness of early treatment with "second-line" antirheumatic drugs. A randomized, controlled trial
-
VAN DER HEIDE, A., JACOBS, J.W., BIJLSMA, J.W., HEURKENS, A.H., VAN BOOMA-FRANKFORT, C., VAN DER VEEN, M.J., HAANEN, H.C., HOFMAN, D.M., VAN ALBADA-KUIPERS, G.A., TER BORG, E.J., BRUS, H.L., DJNANT, H.J., KRUIZE, A.A., and SCHENK, Y. (1996). The effectiveness of early treatment with "second-line" antirheumatic drugs. A randomized, controlled trial. Ann. Intern. Med. 124, 699-707.
-
(1996)
Ann. Intern. Med.
, vol.124
, pp. 699-707
-
-
Van Der Heide, A.1
Jacobs, J.W.2
Bijlsma, J.W.3
Heurkens, A.H.4
Van Booma-Frankfort, C.5
Van Der Veen, M.J.6
Haanen, H.C.7
Hofman, D.M.8
Van Albada-Kuipers, G.A.9
Ter Borg, E.J.10
Brus, H.L.11
Djnant, H.J.12
Kruize, A.A.13
Schenk, Y.14
-
38
-
-
0028143211
-
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
-
ELLIOTT, M.J., MAINI, R.N., FELDMANN, M., KALDEN, J.R., ANTONI, C., SMOLEN, J.S., LEEB, B., BREEDVELD, F.C., MACFARLANE, J.D., BIJL, H., et al. (1994). Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 344, 1105-1110.
-
(1994)
Lancet
, vol.344
, pp. 1105-1110
-
-
Elliott, M.J.1
Maini, R.N.2
Feldmann, M.3
Kalden, J.R.4
Antoni, C.5
Smolen, J.S.6
Leeb, B.7
Breedveld, F.C.8
Macfarlane, J.D.9
Bijl, H.10
-
39
-
-
0023694150
-
Correlation of plasma interleukin 1 levels with disease activity in rheumatoid arthritis
-
EASTGATE, J.A., SYMONS, J.A., WOOD, N.C., GRINLINTON, F.M., DI GIOVINE, F.S., and DUFF, G.W. (1988). Correlation of plasma interleukin 1 levels with disease activity in rheumatoid arthritis. Lancet 2, 706-709.
-
(1988)
Lancet
, vol.2
, pp. 706-709
-
-
Eastgate, J.A.1
Symons, J.A.2
Wood, N.C.3
Grinlinton, F.M.4
Di Giovine, F.S.5
Duff, G.W.6
-
40
-
-
0026684213
-
Determination of cytokines in synovial fluids: Correlation with diagnosis and histomorphological characteristics of synovial tissue
-
KAHLE, P., SAAL, J., SCHAUDT, K., ZACHER, J., FRITZ, P., and PAWELEC, G. (1992). Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of synovial tissue. Ann. Rheum. Dis. 51, 731-734.
-
(1992)
Ann. Rheum. Dis.
, vol.51
, pp. 731-734
-
-
Kahle, P.1
Saal, J.2
Schaudt, K.3
Zacher, J.4
Fritz, P.5
Pawelec, G.6
-
41
-
-
0022492018
-
Enhanced interleukin 1 generation by monocytes in vitro is temporally linked to an early event in the onset of exacerbation of rheumatoid arthritis
-
SHORE, A., JAGLAL, S., and KEYSTONE, E.C. (1986). Enhanced interleukin 1 generation by monocytes in vitro is temporally linked to an early event in the onset of exacerbation of rheumatoid arthritis. Clin. Exp. Immunol. 65, 293-302.
-
(1986)
Clin. Exp. Immunol.
, vol.65
, pp. 293-302
-
-
Shore, A.1
Jaglal, S.2
Keystone, E.C.3
-
42
-
-
0343907263
-
Comparative cytokine gene expression in synovial tissue of early rheumatoid arthritis and seronegative spondyloarthropathies
-
CANETE, J.D., LLENA, J., COLLADO, A., SANMARTI, R., GAYA, A., GRATACOS, J., BLAY, M., and MUNOZ-GOMEZ, J. (1997). Comparative cytokine gene expression in synovial tissue of early rheumatoid arthritis and seronegative spondyloarthropathies. Br. J. Rheumatol. 36, 38-42.
-
(1997)
Br. J. Rheumatol.
, vol.36
, pp. 38-42
-
-
Canete, J.D.1
Llena, J.2
Collado, A.3
Sanmarti, R.4
Gaya, A.5
Gratacos, J.6
Blay, M.7
Munoz-Gomez, J.8
-
43
-
-
0023914715
-
Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients. Possible involvement in joint destruction
-
MIYASAKA, N., SATO, K., GOTO, M., SASANO, M., NATSUYAMA, M., INOUE, K., and NISHIOKA, K. (1988). Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients. Possible involvement in joint destruction. Arthritis Rheum. 31, 480-486.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 480-486
-
-
Miyasaka, N.1
Sato, K.2
Goto, M.3
Sasano, M.4
Natsuyama, M.5
Inoue, K.6
Nishioka, K.7
-
44
-
-
0031939315
-
Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes
-
SASAKI, K., HATTORI, T., FUJISAWA, T., TAKAHASHI, K., INOUE, H., and TAKIGAWA, M. (1998). Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes. J. Biochem. 123, 431-439.
-
(1998)
J. Biochem.
, vol.123
, pp. 431-439
-
-
Sasaki, K.1
Hattori, T.2
Fujisawa, T.3
Takahashi, K.4
Inoue, H.5
Takigawa, M.6
-
45
-
-
0030795025
-
In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs
-
SEITZ, M., LOETSCHER, P., DEWALD, B., TOWBIN, H., and BAGGIOLINI, M. (1997). In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs. J. Rheumatol. 24, 1471-1476.
-
(1997)
J. Rheumatol.
, vol.24
, pp. 1471-1476
-
-
Seitz, M.1
Loetscher, P.2
Dewald, B.3
Towbin, H.4
Baggiolini, M.5
-
47
-
-
0002466558
-
Interferon alpha/beta, gene structure and regulation
-
S. Baron, D.H. Coppenhaver, F. Dianzani, W.R. Fleischmann, T.K. Hughes, G.R. Klimpel, D.W. Niesel, G.J. Stanton, and S.K. Tyring (eds.) Galveston, TX: University of Texas Press
-
DRON, M., and TOVEY, M. (I992). Interferon alpha/beta, gene structure and regulation. In: Interferon: Principles and Medical Applications. S. Baron, D.H. Coppenhaver, F. Dianzani, W.R. Fleischmann, T.K. Hughes, G.R. Klimpel, D.W. Niesel, G.J. Stanton, and S.K. Tyring (eds.) Galveston, TX: University of Texas Press, pp. 33-45.
-
(1992)
Interferon: Principles and Medical Applications
, pp. 33-45
-
-
Dron, M.1
Tovey, M.2
-
48
-
-
0017715086
-
Evaluation of the effects of interferon and interferon inducers on the immune response
-
JOHNSON, H.M., and BARON, S. (1977). Evaluation of the effects of interferon and interferon inducers on the immune response. Pharmacol. Ther. 1, 349-367.
-
(1977)
Pharmacol. Ther.
, vol.1
, pp. 349-367
-
-
Johnson, H.M.1
Baron, S.2
-
49
-
-
0023477128
-
Human interferons: Structure and function
-
ZOON, K.C. (1987). Human interferons: structure and function. Interferon 9, 1-12.
-
(1987)
Interferon
, vol.9
, pp. 1-12
-
-
Zoon, K.C.1
-
50
-
-
0002218492
-
Interferons: Protein structure
-
S. Baron, F. Dianzani, G.J. Stanton, and W.R. Fleischmann (eds.) Austin, TX: University of Texas Press
-
RASHIDBAIGI, A., and PESTKA, S. (1987). Interferons: Protein structure. In: Interferon System. S. Baron, F. Dianzani, G.J. Stanton, and W.R. Fleischmann (eds.) Austin, TX: University of Texas Press, pp. 149-168.
-
(1987)
Interferon System
, pp. 149-168
-
-
Rashidbaigi, A.1
Pestka, S.2
-
51
-
-
0028944489
-
α and β interferons and their receptor and their friends and relations
-
UZE, G., LUTFALLA, G., and KNUDSON, K.E. (1995). α and β Interferons and their receptor and their friends and relations. J. Interferon Cytokine Res. 15, 3-26.
-
(1995)
J. Interferon Cytokine Res.
, vol.15
, pp. 3-26
-
-
Uze, G.1
Lutfalla, G.2
Knudson, K.E.3
-
52
-
-
0020988538
-
Interferon receptors
-
I. Gresser (ed.) New York: Academic Press
-
AGUET, M., and MOGENSEN, K.E. (1983). Interferon receptors. In: Interferons. I. Gresser (ed.) New York: Academic Press, pp. 1-22.
-
(1983)
Interferons
, pp. 1-22
-
-
Aguet, M.1
Mogensen, K.E.2
-
53
-
-
0030460065
-
Oral cytokine administration
-
ROLLWAGEN, R., and BAQAR, S. (1996). Oral cytokine administration. Immunol. Today 17, 548-550.
-
(1996)
Immunol. Today
, vol.17
, pp. 548-550
-
-
Rollwagen, R.1
Baqar, S.2
-
54
-
-
0026683871
-
ser
-
ser. J. Interferon Res. 12, 411-413.
-
(1992)
J. Interferon Res.
, vol.12
, pp. 411-413
-
-
Witt, P.J.1
Goldstein, D.2
Storer, B.E.3
Grossberg, S.E.4
Flashner, M.5
Colby, C.B.6
Borden, E.C.7
-
55
-
-
0026043814
-
Absorption of cytokines via the oropharyngeal associated lymphoid tissues - Does an unorthodox route improve the therapeutic index of interferon?
-
BOCCI, V. (1991). Absorption of cytokines via the oropharyngeal associated lymphoid tissues - does an unorthodox route improve the therapeutic index of interferon? Clin. Pharmacokinet. 21, 411-417.
-
(1991)
Clin. Pharmacokinet.
, vol.21
, pp. 411-417
-
-
Bocci, V.1
-
56
-
-
0024587987
-
Overview of the mucosal immune system
-
BRANDTZAEG, P. (1989). Overview of the mucosal immune system. Curr. Top. Microbiol. Immunol. 146, 13-28.
-
(1989)
Curr. Top. Microbiol. Immunol.
, vol.146
, pp. 13-28
-
-
Brandtzaeg, P.1
-
57
-
-
0020646923
-
Immunosuppression caused by antigen feeding II. Suppressor T cells mask Peyer's patch B cell priming to orally administered antigen
-
MACDONALD, T.T. (1983). Immunosuppression caused by antigen feeding II. Suppressor T cells mask Peyer's patch B cell priming to orally administered antigen. Eur. J. Immunol. 13, 138-142.
-
(1983)
Eur. J. Immunol.
, vol.13
, pp. 138-142
-
-
Macdonald, T.T.1
-
58
-
-
0021233780
-
Immunologic suppression after oral administration of antigen. III. Activation of suppressor-inducer cells in the Peyer's patches
-
MATTINGLY, J.A. (1984). Immunologic suppression after oral administration of antigen. III. Activation of suppressor-inducer cells in the Peyer's patches. Cell. Immunol. 86, 46-52.
-
(1984)
Cell. Immunol.
, vol.86
, pp. 46-52
-
-
Mattingly, J.A.1
-
59
-
-
0025356871
-
The downregulation of IFN-α receptors in human lymphoblastoid cells: Relation of cellular responsiveness to antiproliferative action of IFN-α
-
PFEFFER, L.M., and DONNER, D.D. (1990). The downregulation of IFN-α receptors in human lymphoblastoid cells: relation of cellular responsiveness to antiproliferative action of IFN-α. Cancer Res. 50, 2654-2657.
-
(1990)
Cancer Res.
, vol.50
, pp. 2654-2657
-
-
Pfeffer, L.M.1
Donner, D.D.2
-
60
-
-
0026337403
-
Transmembrane signalling by interferon-α
-
PFEFFER, L.M., and COLAMONICI, O.R. (1991). Transmembrane signalling by interferon-α. Pharmacol. Ther. 52, 149-151.
-
(1991)
Pharmacol. Ther.
, vol.52
, pp. 149-151
-
-
Pfeffer, L.M.1
Colamonici, O.R.2
-
61
-
-
0026746424
-
Orally administered interferons exert their white blood cell suppressive effects via a novel mechanism
-
FLEISCHMANN, W.R., Jr., KOREN, S., and FLEISCHMANN, C.M. (1992). Orally administered interferons exert their white blood cell suppressive effects via a novel mechanism. Proc. Soc. Exp. Biol. Med. 201, 200-207.
-
(1992)
Proc. Soc. Exp. Biol. Med.
, vol.201
, pp. 200-207
-
-
Fleischmann W.R., Jr.1
Koren, S.2
Fleischmann, C.M.3
-
62
-
-
0033023857
-
Oromucosal interferon therapy: Pharmacokinetics and pharmacodynamics
-
EID, P., MERITET, J.F., MAURY, C., LASFAR, A., WEILL, D., and TOVEY, M.G. (1999). Oromucosal interferon therapy: pharmacokinetics and pharmacodynamics. J. Interferon Cytokine Res. 19, 157-169.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 157-169
-
-
Eid, P.1
Meritet, J.F.2
Maury, C.3
Lasfar, A.4
Weill, D.5
Tovey, M.G.6
-
63
-
-
0015794874
-
Circulating interferon in rabbits after administration of human interferon by different routes
-
CANTELL, K., and PYHALA, L. (1973). Circulating interferon in rabbits after administration of human interferon by different routes. J. Gen. Virol. 20, 97-104.
-
(1973)
J. Gen. Virol.
, vol.20
, pp. 97-104
-
-
Cantell, K.1
Pyhala, L.2
-
64
-
-
0021952777
-
Pharmacokinetics of recombinant leukocyte A interferon following various routes and modes of administration to the dog
-
GIBSON, D.M., COTLER, S., SPIEGEL, H.E., and COLBURN, W.A. (1985). Pharmacokinetics of recombinant leukocyte A interferon following various routes and modes of administration to the dog. J. Interferon Res. 5, 403-408.
-
(1985)
J. Interferon Res.
, vol.5
, pp. 403-408
-
-
Gibson, D.M.1
Cotler, S.2
Spiegel, H.E.3
Colburn, W.A.4
-
65
-
-
0021251277
-
Pharmacokinetics of recombinant alpha A interferon following I.V. infusion and bolus, I.M., and P.O. administrations to African green monkeys
-
WILLS, R.J., SPIEGEL, H.E., and SOIKE, K.F. (1984). Pharmacokinetics of recombinant alpha A interferon following I.V. infusion and bolus, I.M., and P.O. administrations to African green monkeys. J. Interferon Res. 4, 399-409.
-
(1984)
J. Interferon Res.
, vol.4
, pp. 399-409
-
-
Wills, R.J.1
Spiegel, H.E.2
Soike, K.F.3
-
66
-
-
0001613208
-
Mx protein: Function and mechanism of action
-
S. Baron, D.H. Coppenhaver, F. Dianzani, W.R. Fleischmann, T.K. Hughes, G.R. Klimpel, D.W. Niesel, G.J. Stanton, and S.K. Tyring (eds.) Galveston, TX: University of Texas Press
-
HORISBERGER, M.A. (1992). Mx protein: function and mechanism of action. In: Interferon: Principles and Medical Applications. S. Baron, D.H. Coppenhaver, F. Dianzani, W.R. Fleischmann, T.K. Hughes, G.R. Klimpel, D.W. Niesel, G.J. Stanton, and S.K. Tyring (eds.) Galveston, TX: University of Texas Press, pp. 215-224.
-
(1992)
Interferon: Principles and Medical Applications
, pp. 215-224
-
-
Horisberger, M.A.1
-
67
-
-
0028274170
-
MxA gene expression after live vires vaccination: A sensitive marker for endogenous type I interferon
-
ROERS, A., HOCHKEPPEL, H., HORISBERGER, M., HOVANESSIAN, A., and HALLER, O. (1994). MxA gene expression after live vires vaccination: a sensitive marker for endogenous type I interferon. J. Infect. Dis. 169, 807-813.
-
(1994)
J. Infect. Dis.
, vol.169
, pp. 807-813
-
-
Roers, A.1
Hochkeppel, H.2
Horisberger, M.3
Hovanessian, A.4
Haller, O.5
-
68
-
-
0029985565
-
Oral administration of IFN-alpha is superior to subcutaneous administration of IFN-alpha in the suppression of chronic relapsing experimental autoimmune encephalomyelitis
-
BROD, S.A., and KHAN, M. (1996). Oral administration of IFN-alpha is superior to subcutaneous administration of IFN-alpha in the suppression of chronic relapsing experimental autoimmune encephalomyelitis. J. Autoimmun. 9, 11-20.
-
(1996)
J. Autoimmun.
, vol.9
, pp. 11-20
-
-
Brod, S.A.1
Khan, M.2
-
69
-
-
0033019248
-
Ingested interferon alpha induces Mx mRNA
-
BROD, S.A., NELSON, L., JIN, R., and WOLINSKY, J.S. (1999). Ingested interferon alpha induces Mx mRNA. Cytokine 11, 492-499.
-
(1999)
Cytokine
, vol.11
, pp. 492-499
-
-
Brod, S.A.1
Nelson, L.2
Jin, R.3
Wolinsky, J.S.4
-
70
-
-
0030498666
-
IFN-β1b decreases the migration of T lymphocytes in vitro - Effects on matrix metalloproteinase-9
-
STUVE, O., DOOLEY. N., UHM, H., ANTEL, J., FRANCIS, G., WILLIAMS, G., and YONG, V. (1996). IFN-β1b decreases the migration of T lymphocytes in vitro - effects on matrix metalloproteinase-9. Ann. Neurol. 40, 853-863.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 853-863
-
-
Stuve, O.1
Dooley, N.2
Uhm, H.3
Antel, J.4
Francis, G.5
Williams, G.6
Yong, V.7
-
71
-
-
0032880358
-
Migratory behavior of lymphocytes isolated from multiple sclerosis patients: Effects of interferon beta-1b therapy
-
UHM, J.H., DOOLEY, N.P., STUVE, O., FRANCIS, G.S., DUQUETTE, P., ANTEL, J.P., and YONG, V.W. (1999). Migratory behavior of lymphocytes isolated from multiple sclerosis patients: effects of interferon beta-1b therapy. Ann. Neurol. 46, 319-324.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 319-324
-
-
Uhm, J.H.1
Dooley, N.P.2
Stuve, O.3
Francis, G.S.4
Duquette, P.5
Antel, J.P.6
Yong, V.W.7
-
72
-
-
0028936221
-
The interferons: Biological effects, mechanism of action, and use in multiple sclerosis
-
WEINSTOCK-GUTTMANN, B., RANSAHOFF, R.M., KINKEL, R.P., and RUDICK, R.A. (1995). The interferons: biological effects, mechanism of action, and use in multiple sclerosis. Ann. Neurol. 37, 7-15.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 7-15
-
-
Weinstock-Guttmann, B.1
Ransahoff, R.M.2
Kinkel, R.P.3
Rudick, R.A.4
-
73
-
-
0035845612
-
Ingested IFN-α: Results of a pilot study in relapsing-remitting multiple sclerosis (RRMS)
-
BROD, S., LINDSEY, J., VRIESENDORP, F., AHN, C., NARAYANA, P., and WOLINSKY, J. (2001). Ingested IFN-α: results of a pilot study in relapsing-remitting multiple sclerosis (RRMS). Neurology 57, 845-852.
-
(2001)
Neurology
, vol.57
, pp. 845-852
-
-
Brod, S.1
Lindsey, J.2
Vriesendorp, F.3
Ahn, C.4
Narayana, P.5
Wolinsky, J.6
-
74
-
-
0034117395
-
Adoptive transfer from interferon-alpha-fed mice is associated with inhibition of active experimental autoimmune encephalomyelitis by decreasing recipient tumor necrosis factor-alpha secretion
-
BROD, S.A., KHAN, M., NELSON, L.D., DECUIR, B., MALONE, M., and HENNINGER, E. (2000). Adoptive transfer from interferon-alpha-fed mice is associated with inhibition of active experimental autoimmune encephalomyelitis by decreasing recipient tumor necrosis factor-alpha secretion. J. Immunother. 23, 235-245.
-
(2000)
J. Immunother.
, vol.23
, pp. 235-245
-
-
Brod, S.A.1
Khan, M.2
Nelson, L.D.3
Decuir, B.4
Malone, M.5
Henninger, E.6
-
75
-
-
0031782993
-
Ingested IFN-α suppresses IDDM in the NOD mouse
-
BROD, S., DARCAN, S., MALONE, M., PAPPOLLA, M., and NELSON, L. (1998). Ingested IFN-α suppresses IDDM in the NOD mouse. Diabetologia 41, 1227-1232.
-
(1998)
Diabetologia
, vol.41
, pp. 1227-1232
-
-
Brod, S.1
Darcan, S.2
Malone, M.3
Pappolla, M.4
Nelson, L.5
-
76
-
-
0029091751
-
Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft
-
RABINOVITCH, A., SUAREZ-PINZON, W.L., SORENSEN, O., BLEACKLEY, R.C., POWER, R.F., and RAJOTTE, R.V. (1995). Combined therapy with interleukin-4 and interleukin-10 inhibits autoimmune diabetes recurrence in syngeneic islet-transplanted nonobese diabetic mice. Analysis of cytokine mRNA expression in the graft. Transplantation 60, 368-374.
-
(1995)
Transplantation
, vol.60
, pp. 368-374
-
-
Rabinovitch, A.1
Suarez-Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
Power, R.F.5
Rajotte, R.V.6
-
77
-
-
0029810079
-
Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10
-
FAUST, A., ROTHE, H., SCHADE, U., LAMPETER, E., and KOLB, H. (1996). Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10. Transplantation 62, 648-652.
-
(1996)
Transplantation
, vol.62
, pp. 648-652
-
-
Faust, A.1
Rothe, H.2
Schade, U.3
Lampeter, E.4
Kolb, H.5
-
78
-
-
0028964995
-
Modification of acute experimental autoimmune encephalomyelitis in the Lewis rat by oral administration of type I interferons
-
BROD, S.A., SCOTT, M., BURNS, D.K., and PHILLIPS, J.T. (1995). Modification of acute experimental autoimmune encephalomyelitis in the Lewis rat by oral administration of type I interferons. J. Interferon Cytokine Res. 15, 115-122.
-
(1995)
J. Interferon Cytokine Res.
, vol.15
, pp. 115-122
-
-
Brod, S.A.1
Scott, M.2
Burns, D.K.3
Phillips, J.T.4
-
79
-
-
0032146350
-
Treatment of Guillain-Barré syndrome with interferon-beta
-
CREANGE, A., LERAT, H., MEYRIGNAC, C., DEGOS, J.D., GHERARDI, R.K., and CESARO, P. (1998). Treatment of Guillain-Barré syndrome with interferon-beta [Letter]. Lancet 352, 368-369.
-
(1998)
Lancet
, vol.352
, pp. 368-369
-
-
Creange, A.1
Lerat, H.2
Meyrignac, C.3
Degos, J.D.4
Gherardi, R.K.5
Cesaro, P.6
-
80
-
-
0030454489
-
Oral administration of type I interferon modulates the course of experimental allergic neuritis
-
VRIESENDORP, F.J., FLYNN, R.E., KHAN, M., PAPPOLLA, M.A., and BROD, S.A. (1996). Oral administration of type I interferon modulates the course of experimental allergic neuritis. Autoimmunity 24, 157-165.
-
(1996)
Autoimmunity
, vol.24
, pp. 157-165
-
-
Vriesendorp, F.J.1
Flynn, R.E.2
Khan, M.3
Pappolla, M.A.4
Brod, S.A.5
-
81
-
-
0022358735
-
Chronic relapsing experimental allergic encephalomyelitis in the lewis rat
-
FEUER, C., PRENTICE, D.E., and CAMMISULI, S. (1985). Chronic relapsing experimental allergic encephalomyelitis in the lewis rat. J. Neuroimmunol. 10, 159-166.
-
(1985)
J. Neuroimmunol.
, vol.10
, pp. 159-166
-
-
Feuer, C.1
Prentice, D.E.2
Cammisuli, S.3
-
82
-
-
0017670674
-
Animal models for multiple sclerosis: Chronic experimental allergic encephalomyelitis in inbred guinea pigs
-
RAINE, C.S., and STONE, S.H. (1977). Animal models for multiple sclerosis: chronic experimental allergic encephalomyelitis in inbred guinea pigs. NY State J. Med. 77, 1693-1696.
-
(1977)
NY State J. Med.
, vol.77
, pp. 1693-1696
-
-
Raine, C.S.1
Stone, S.H.2
-
83
-
-
0017452304
-
Chronic relapsing experimental allergic encephalomyelitis: An experimental model of multiple sclerosis
-
WISNEWSKI, H.M., and KEITH, A.B. (1977). Chronic relapsing experimental allergic encephalomyelitis: an experimental model of multiple sclerosis. Ann. Neurol. 1, 144-148.
-
(1977)
Ann. Neurol.
, vol.1
, pp. 144-148
-
-
Wisnewski, H.M.1
Keith, A.B.2
-
84
-
-
0028236020
-
Suppression of relapsing experimental autoimmune encephalomyelitis in the SJL/J mouse by oral administration of type I interferons
-
BROD, S.A., and BURNS, D.K. (1994). Suppression of relapsing experimental autoimmune encephalomyelitis in the SJL/J mouse by oral administration of type I interferons. Neurology 44, 1144-1148.
-
(1994)
Neurology
, vol.44
, pp. 1144-1148
-
-
Brod, S.A.1
Burns, D.K.2
-
85
-
-
0024334434
-
Structure-function studies of interferons-α: Amino acid substitutions at the conserved residue tyrosine 123 in human interferons-α
-
McINNES, M., CHAMBERS, P.J., CHEETHAM, B.F., BEILHARZ, M.W., and TYMMS, M.J. (1989). Structure-function studies of interferons-α: amino acid substitutions at the conserved residue tyrosine 123 in human interferons-α. J. Interferon Res. 9, 305-314.
-
(1989)
J. Interferon Res.
, vol.9
, pp. 305-314
-
-
McInnes, M.1
Chambers, P.J.2
Cheetham, B.F.3
Beilharz, M.W.4
Tymms, M.J.5
-
86
-
-
0023298866
-
Single amino acid changes that render human IFN-α2 biologically active on mouse cells
-
WEBER, H., VALENZUELA, D., LUJGER, G., GUBLER, M., and WEISSMAN, C. (1987). Single amino acid changes that render human IFN-α2 biologically active on mouse cells. EMBO J. 6, 591-598.
-
(1987)
EMBO J.
, vol.6
, pp. 591-598
-
-
Weber, H.1
Valenzuela, D.2
Lujger, G.3
Gubler, M.4
Weissman, C.5
-
87
-
-
0028903315
-
Oral administration of human or murine interferon alpha suppresses relapses and modifies adoptive transfer in experimental autoimmune encephalomyelitis
-
BROD, S.A., KHAN, M., KERMAN, R.H., and PAPPOLLA, M. (1995). Oral administration of human or murine interferon alpha suppresses relapses and modifies adoptive transfer in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 58, 61-69.
-
(1995)
J. Neuroimmunol.
, vol.58
, pp. 61-69
-
-
Brod, S.A.1
Khan, M.2
Kerman, R.H.3
Pappolla, M.4
-
88
-
-
0021948231
-
Adoptive transfer of murine relapsing experimental autoimmune encephalomyelitis
-
LUBLIN, F. (1985). Adoptive transfer of murine relapsing experimental autoimmune encephalomyelitis. Ann. Neurol. 17, 188-190.
-
(1985)
Ann. Neurol.
, vol.17
, pp. 188-190
-
-
Lublin, F.1
-
89
-
-
0020036035
-
Passive transfer of experimental allergic encephalomyelitis in the Lewis rat with activated spleen cells: Differential activation with mitogens
-
PETERS, B.A., and HINRICHS, D.J. (1982). Passive transfer of experimental allergic encephalomyelitis in the Lewis rat with activated spleen cells: differential activation with mitogens. Cell. Immunol. 69, 175-185.
-
(1982)
Cell. Immunol.
, vol.69
, pp. 175-185
-
-
Peters, B.A.1
Hinrichs, D.J.2
-
90
-
-
0026027162
-
Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer demyelinating relapsing experimental autoimmune encephalomyelitis
-
WHITHAM, R.H., BOURDETTE, D.N., HASHIM, G.A., HERNDON, R.M., ILG, R.C., VANDENBARK, A.A., and OFFNER, H. (1991). Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer demyelinating relapsing experimental autoimmune encephalomyelitis. J. Immunol. 146, 101-107.
-
(1991)
J. Immunol.
, vol.146
, pp. 101-107
-
-
Whitham, R.H.1
Bourdette, D.N.2
Hashim, G.A.3
Herndon, R.M.4
Ilg, R.C.5
Vandenbark, A.A.6
Offner, H.7
-
91
-
-
0027521002
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial
-
UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group
-
PATY, D.W., and LI, D.K. (1993). Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group. Neurology 43, 662-667.
-
(1993)
Neurology
, vol.43
, pp. 662-667
-
-
Paty, D.W.1
Li, D.K.2
-
92
-
-
0030777027
-
High IL-6 and low IL-10 in the central nervous system are associated with protracted relapsing EAE in DA rats
-
DIAB, A., ZHU, J., XIAO, B., MUSTAFA, M., and LINK, H. (1997). High IL-6 and low IL-10 in the central nervous system are associated with protracted relapsing EAE in DA rats. J. Neuropathol. Exp. Neurol. 56, 641-650.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 641-650
-
-
Diab, A.1
Zhu, J.2
Xiao, B.3
Mustafa, M.4
Link, H.5
-
93
-
-
0030248470
-
Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: Persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta
-
ISSAZADEH, S., LORENTZEN, J., MUSTAFA, M., HOJEBERG, B., MUSSENER, A., and OLSSON, T. (1996). Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta. J. Neuroimmunol. 69, 103-115.
-
(1996)
J. Neuroimmunol.
, vol.69
, pp. 103-115
-
-
Issazadeh, S.1
Lorentzen, J.2
Mustafa, M.3
Hojeberg, B.4
Mussener, A.5
Olsson, T.6
-
94
-
-
0031463988
-
Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells
-
COCLET-NINIM, J., DAYER, J.M., and BURGER, D. (1997). Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells. Eur. Cytokine Netw. 8, 345-349.
-
(1997)
Eur. Cytokine Netw.
, vol.8
, pp. 345-349
-
-
Coclet-Ninim, J.1
Dayer, J.M.2
Burger, D.3
-
95
-
-
0026781817
-
Type I interferons (IFN-alpha and -beta) suppress cytotoxin (tumor necrosis factor-alpha and lymphotoxin) production by mitogen-stimulated human peripheral blood mononuclear cell
-
ABU-KHABAR, K.S., ARMSTRONG, J.A., and HO, M. (1992). Type I interferons (IFN-alpha and -beta) suppress cytotoxin (tumor necrosis factor-alpha and lymphotoxin) production by mitogen-stimulated human peripheral blood mononuclear cell. J. Leukocyte Biol. 52, 165-172.
-
(1992)
J. Leukocyte Biol.
, vol.52
, pp. 165-172
-
-
Abu-Khabar, K.S.1
Armstrong, J.A.2
Ho, M.3
-
96
-
-
0028985427
-
Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans
-
TILG, H., VOGEL, W., and DINARELLO, C.A. (1995). Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans. Blood 85, 433-435.
-
(1995)
Blood
, vol.85
, pp. 433-435
-
-
Tilg, H.1
Vogel, W.2
Dinarello, C.A.3
-
97
-
-
0028987125
-
Decreased CD3-mediated interferon-gamma production in relapsing-remitting multiple sclerosis
-
BROD, S.A., KHAN, M., BRIGHT. J., SRIRAM, S., MARSHALL, G.D., Jr., HENNINGER, E.M., KERMAN, R.H., and WOLINSKY, J.S. (1995). Decreased CD3-mediated interferon-gamma production in relapsing-remitting multiple sclerosis. Ann. Neurol. 37, 546-549.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 546-549
-
-
Brod, S.A.1
Khan, M.2
Bright, J.3
Sriram, S.4
Marshall G.D., Jr.5
Henninger, E.M.6
Kerman, R.H.7
Wolinsky, J.S.8
-
98
-
-
0036554140
-
Interferon-alpha as an immunotherapeutic protein
-
BRASSARD, D.L., GRACE, M.J., and BORDENS, R.W. (2002). Interferon-alpha as an immunotherapeutic protein. J. Leukocyte Biol. 71, 565-581.
-
(2002)
J. Leukocyte Biol.
, vol.71
, pp. 565-581
-
-
Brassard, D.L.1
Grace, M.J.2
Bordens, R.W.3
-
99
-
-
0034803591
-
Th1/th2 type cytokines in hepatitis B patients treated with interferon-alpha
-
XING. T., ZHANG, L., LU, Q., HOU, J., FENG, X., and LUO, K. (2001). Th1/th2 type cytokines in hepatitis B patients treated with interferon-alpha. Chin. Med. J. (Engl.) 114, 921-924.
-
(2001)
Chin. Med. J. (Engl.)
, vol.114
, pp. 921-924
-
-
Xing, T.1
Zhang, L.2
Lu, Q.3
Hou, J.4
Feng, X.5
Luo, K.6
-
100
-
-
0034843855
-
Interferon-alpha drives T cell-mediated immunopathology in the intestine
-
MONTELEONE, G., PENDER, S.L., WATHEN, N.C., and MACDONALD, T.T. (2001). Interferon-alpha drives T cell-mediated immunopathology in the intestine. Eur. J. Immunol. 31, 2247-2255.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2247-2255
-
-
Monteleone, G.1
Pender, S.L.2
Wathen, N.C.3
Macdonald, T.T.4
-
101
-
-
0030946161
-
Ingested IFN-alpha has biological effects in humans with relapsing-remitting multiple sclerosis
-
BROD, S.A., KERMAN, R.H., NELSON, L.D., MARSHALL, G.D., Jr., HENNINGER, E.M., KHAN, M., JIN, R., and WOLINSKY, J.S. (1997). Ingested IFN-alpha has biological effects in humans with relapsing-remitting multiple sclerosis. Mult. Scler. 3, 1-7.
-
(1997)
Mult. Scler.
, vol.3
, pp. 1-7
-
-
Brod, S.A.1
Kerman, R.H.2
Nelson, L.D.3
Marshall G.D., Jr.4
Henninger, E.M.5
Khan, M.6
Jin, R.7
Wolinsky, J.S.8
-
102
-
-
0034720549
-
Ingested interferon-alpha prevents allograft islet transplant rejection
-
BROD, S.A., KATZ, S., PHAN, T., and STEPKOWSKI, S. (2000). Ingested interferon-alpha prevents allograft islet transplant rejection. Transplantation 69, 2162-2166.
-
(2000)
Transplantation
, vol.69
, pp. 2162-2166
-
-
Brod, S.A.1
Katz, S.2
Phan, T.3
Stepkowski, S.4
-
103
-
-
0035701950
-
Ingested IFN-α preserves residual β cell function in type I diabetes
-
BROD, S., ATKINSON, M., LAVIS, V., BROSNAN, P., HARDIN, D., ORLANDER, P.R., NUYGEN, M., and RILEY, W. (2001). Ingested IFN-α preserves residual β cell function in type I diabetes. J. Interferon Cytokine Res. 21, 1021-1030.
-
(2001)
J. Interferon Cytokine Res.
, vol.21
, pp. 1021-1030
-
-
Brod, S.1
Atkinson, M.2
Lavis, V.3
Brosnan, P.4
Hardin, D.5
Orlander, P.R.6
Nuygen, M.7
Riley, W.8
-
104
-
-
0027966060
-
The present knowledge of the inflammatory process and the inflammatory mediators
-
LEIRISALO-REPO, M. (1994). The present knowledge of the inflammatory process and the inflammatory mediators. Pharmacol. Toxicol. 75, 1-3.
-
(1994)
Pharmacol. Toxicol.
, vol.75
, pp. 1-3
-
-
Leirisalo-Repo, M.1
-
105
-
-
0030222167
-
IL-8/NAP-1 is the major T-cell chemoattractant in synovial tissues of rheumatoid arthritis
-
NISHIURA, H., TANAKA, J., TAKEYA, M., TSUKANO, M., KAMBARA, T., and IMAMURA, T. (1996). IL-8/NAP-1 is the major T-cell chemoattractant in synovial tissues of rheumatoid arthritis. Clin. Immunol. Immunopathol. 80, 179-184.
-
(1996)
Clin. Immunol. Immunopathol.
, vol.80
, pp. 179-184
-
-
Nishiura, H.1
Tanaka, J.2
Takeya, M.3
Tsukano, M.4
Kambara, T.5
Imamura, T.6
-
106
-
-
0027957152
-
Induction of IL-8 expression in T cells uses the CD28 costimulatory pathway
-
WECHSLER, A., GORDON, M., DENDORFER, U., and LECLAIR, K. (1994). Induction of IL-8 expression in T cells uses the CD28 costimulatory pathway. J. Immunol. 1531, 2515-2523.
-
(1994)
J. Immunol.
, vol.1531
, pp. 2515-2523
-
-
Wechsler, A.1
Gordon, M.2
Dendorfer, U.3
Leclair, K.4
-
107
-
-
0030904612
-
Elevated cytokine messenger RNA levels in the peripheral blood of patients with rheumatoid arthritis suggest different degrees of myeloid cell activation
-
SCHULZE-KOOPS, H., DAVIS, L.S., KAVANAUGH, A.F., and LIPSKY, P.E. (1997). Elevated cytokine messenger RNA levels in the peripheral blood of patients with rheumatoid arthritis suggest different degrees of myeloid cell activation. Arthritis Rheum. 40, 639-647.
-
(1997)
Arthritis Rheum.
, vol.40
, pp. 639-647
-
-
Schulze-Koops, H.1
Davis, L.S.2
Kavanaugh, A.F.3
Lipsky, P.E.4
-
108
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
ARNETT, F., EDWORTHY, S., BLOCH, D., McSHANE, D., FRIES, J., COOPER, N., HEALEY, L., KAPLAN, S., LIANG, M., LUTHRA, H., MEDSGER, T., MITCHELL, D., NEUSTADT, D., PINELS, R., SCHALLER, J., SHARP, J., WILDER, R., and HUNDER, G. (1988). The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31, 315-324.
-
(1988)
Arthritis Rheum.
, vol.31
, pp. 315-324
-
-
Arnett, F.1
Edworthy, S.2
Bloch, D.3
McShane, D.4
Fries, J.5
Cooper, N.6
Healey, L.7
Kaplan, S.8
Liang, M.9
Luthra, H.10
Medsger, T.11
Mitchell, D.12
Neustadt, D.13
Pinels, R.14
Schaller, J.15
Sharp, J.16
Wilder, R.17
Hunder, G.18
-
109
-
-
0034457130
-
Ingested IFN-α has biological effects in rheumatoid arthritis
-
BROD, S.A., FRIEDMAN, A.W., APPLEYARD, J., WARNER, N.B., and HENNINGER, E.M. (2001). Ingested IFN-α has biological effects in rheumatoid arthritis. Int. J. Immunother. 16, 53-57.
-
(2001)
Int. J. Immunother.
, vol.16
, pp. 53-57
-
-
Brod, S.A.1
Friedman, A.W.2
Appleyard, J.3
Warner, N.B.4
Henninger, E.M.5
-
110
-
-
0025318862
-
Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function
-
DAYNES, R.A., ARANEO, B.A., DOWELL, T.A., HUANG, K., and DUDLEY, D. (1990). Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J. Exp. Med. 171, 979-996.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 979-996
-
-
Daynes, R.A.1
Araneo, B.A.2
Dowell, T.A.3
Huang, K.4
Dudley, D.5
-
111
-
-
0023895986
-
Roles of interferon produced in physiological conditions. A speculative review
-
BOCCI, V. (1988). Roles of interferon produced in physiological conditions. A speculative review. Immunology 64, 1-9.
-
(1988)
Immunology
, vol.64
, pp. 1-9
-
-
Bocci, V.1
-
112
-
-
0031900178
-
Single-blinded controlled trial of low-dose oral IFN-alpha for the treatment of xerostomia in patients with Sjögren's syndrome
-
SHIOZAWA, S., TANAKA, Y., and SHIOZAWA, K. (1998). Single-blinded controlled trial of low-dose oral IFN-alpha for the treatment of xerostomia in patients with Sjögren's syndrome. J. Interferon Cytokine Res. 18, 255-262.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 255-262
-
-
Shiozawa, S.1
Tanaka, Y.2
Shiozawa, K.3
-
113
-
-
0033174272
-
Treatment of primary Sjögren's syndrome with low-dose natural human interferon-alpha administered by the oral mucosal route: A phase II clinical trial
-
IFN Protocol Study Group
-
SHIP, J.A., FOX, P.C., MICHALEK, J.E., CUMMINS, M.J., and RICHARDS, A.B. (1999). Treatment of primary Sjögren's syndrome with low-dose natural human interferon-alpha administered by the oral mucosal route: a phase II clinical trial. IFN Protocol Study Group. J. Interferon Cytokine Res. 19, 943-951.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 943-951
-
-
Ship, J.A.1
Fox, P.C.2
Michalek, J.E.3
Cummins, M.J.4
Richards, A.B.5
-
114
-
-
0032817561
-
Efficacy of low-dose oral use of type I interferon in cytomegalovirus infections in vivo
-
BOSIO, E., BEILHARZ, M.W., WATSON, M.W., and LAWSON, C.M. (1999). Efficacy of low-dose oral use of type I interferon in cytomegalovirus infections in vivo. J. Interferon Cytokine Res. 19, 869-876.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 869-876
-
-
Bosio, E.1
Beilharz, M.W.2
Watson, M.W.3
Lawson, C.M.4
-
115
-
-
0032839875
-
Suppression of late asthmatic response by low-dose oral administration of interferon-beta in the guinea pig model of asthma
-
SATOH, Y., KASAMA, K., KUWABARA, M., YIMIN, DIAO, H.Y., NAKAJIMA, H., KOHANAWA, M., and MINAGAWA, T. (1999). Suppression of late asthmatic response by low-dose oral administration of interferon-beta in the guinea pig model of asthma. J. Interferon Cytokine Res. 19, 887-894.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 887-894
-
-
Satoh, Y.1
Kasama, K.2
Kuwabara, M.3
Yimin4
Diao, H.Y.5
Nakajima, H.6
Kohanawa, M.7
Minagawa, T.8
-
116
-
-
0003084570
-
Regulation of angiogenesis by type I interferon
-
FIDLER, I. (2000). Regulation of angiogenesis by type I interferon. Eur. Cyt. Netw. 11, 96.
-
(2000)
Eur. Cyt. Netw.
, vol.11
, pp. 96
-
-
Fidler, I.1
-
117
-
-
0001844847
-
Stat-induced Stat-inhibitor-1 (SSI-1) inhibits not only IFN-gamma signaling but also IL-4 signaling
-
FUJIMOTO, M., NAKA, T., TSUTSUI, H., KAWAZOC, Y., MORITA, Y., NAKAGAWA, R., NARAZAKI, M., and YOSHIMOTO, T. (2000). Stat-induced Stat-inhibitor-1 (SSI-1) inhibits not only IFN-gamma signaling but also IL-4 signaling. Eur. Cyt. Netw. 11, 47.
-
(2000)
Eur. Cyt. Netw.
, vol.11
, pp. 47
-
-
Fujimoto, M.1
Naka, T.2
Tsutsui, H.3
Kawazoc, Y.4
Morita, Y.5
Nakagawa, R.6
Narazaki, M.7
Yoshimoto, T.8
-
118
-
-
0003144648
-
The effects of IL-6 and LPS on the expression of SOCS by enterocytes
-
OGLE, C.K., and GUO, X. (2000). The effects of IL-6 and LPS on the expression of SOCS by enterocytes. Eur. Cyt. Netw. 11, 46.
-
(2000)
Eur. Cyt. Netw.
, vol.11
, pp. 46
-
-
Ogle, C.K.1
Guo, X.2
-
119
-
-
0032567353
-
The suppressor of cytokine signaling (SOCS) 1 and OCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities
-
SONG, M.M., and SHUAI, K. (1998). The suppressor of cytokine signaling (SOCS) 1 and OCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities. J. Biol. Chem. 273, 35056-35062.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35056-35062
-
-
Song, M.M.1
Shuai, K.2
-
120
-
-
0035845612
-
Ingested IFN-alpha: Results of a pilot study in relapsing-remitting MS
-
BROD, S.A., LINDSEY, J.W., VRIESENDORP, F.S., AHN, C., HENNINGER, E., NARAYANA, P.A., and WOLINSKY, J.S. (2001). Ingested IFN-alpha: results of a pilot study in relapsing-remitting MS. Neurology 57, 845-852.
-
(2001)
Neurology
, vol.57
, pp. 845-852
-
-
Brod, S.A.1
Lindsey, J.W.2
Vriesendorp, F.S.3
Ahn, C.4
Henninger, E.5
Narayana, P.A.6
Wolinsky, J.S.7
-
121
-
-
0027361154
-
Prolonged subcutaneous administration of recombinant alpha 2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: Effect on remission duration and survival - Cancer and Leukemia Group B study 8583
-
OZER, H., GEORGE, S.L., SCHIFFER, C.A., RAO, K., RAO, P.N., WURSTER-HILL, D.H., ARTHUR, D.D., POWELL, B., GOTTLIEB, A., PETERSON, B.A., et al. (1993). Prolonged subcutaneous administration of recombinant alpha 2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: Cancer and Leukemia Group B study 8583. Blood 82, 2975-2984.
-
(1993)
Blood
, vol.82
, pp. 2975-2984
-
-
Ozer, H.1
George, S.L.2
Schiffer, C.A.3
Rao, K.4
Rao, P.N.5
Wurster-Hill, D.H.6
Arthur, D.D.7
Powell, B.8
Gottlieb, A.9
Peterson, B.A.10
-
122
-
-
0033372623
-
Available options for treatment of interferon nonresponders
-
BACON, B.R. (1999). Available options for treatment of interferon nonresponders. Am. J. Med. 107, 67S-70S.
-
(1999)
Am. J. Med.
, vol.107
-
-
Bacon, B.R.1
-
123
-
-
0033849496
-
Contrasting responses to interferon beta-1b treatment in relapsing-remitting multiple sclerosis: Does baseline interleukin-12p35 messenger RNA predict the efficacy of treatment?
-
VAN BOXEL-DEZAIRE, A.H., VAN TRIGT-HOFF, S.C., KILLESTEIN, J., SCHRIJVER, H.M., VAN HOUWELINGEN, J.C., POLMAN, C.H., and NAGELKERKEN, L. (2000). Contrasting responses to interferon beta-1b treatment in relapsing-remitting multiple sclerosis: does baseline interleukin-12p35 messenger RNA predict the efficacy of treatment? Ann. Neurol. 48, 313-322.
-
(2000)
Ann. Neurol.
, vol.48
, pp. 313-322
-
-
Van Boxel-Dezaire, A.H.1
Van Trigt-Hoff, S.C.2
Killestein, J.3
Schrijver, H.M.4
Van Houwelingen, J.C.5
Polman, C.H.6
Nagelkerken, L.7
-
124
-
-
0026661047
-
Distribution of interferon-gamma receptor in human tissues
-
VALENTE, G., OZMEN, L., NOVELLI, F., GEUNA, M., PALESTRO, G., FORNI, G., and GAROTTA, G. (1992). Distribution of interferon-gamma receptor in human tissues. Eur. J. Immunol. 22, 2403-2412.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2403-2412
-
-
Valente, G.1
Ozmen, L.2
Novelli, F.3
Geuna, M.4
Palestro, G.5
Forni, G.6
Garotta, G.7
-
125
-
-
0034544374
-
Expression of HuIFN-alphaR2 chain of type I interferon receptor in human hepatocellular carcinoma and non-cancerous tissues
-
TAKAYAMA, A., YANO, H., OGASAWARA, S., HIGAKI, K., and KOJIRO, M. (2000). Expression of HuIFN-alphaR2 chain of type I interferon receptor in human hepatocellular carcinoma and non-cancerous tissues. Int. J. Mol. Med. 6, 621-627.
-
(2000)
Int. J. Mol. Med.
, vol.6
, pp. 621-627
-
-
Takayama, A.1
Yano, H.2
Ogasawara, S.3
Higaki, K.4
Kojiro, M.5
-
126
-
-
0032030169
-
The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: Effects on JAK-Stat activation and receptor down-regulation
-
BASU, L., YANG, C.H., MURTI, A., GARCIA, J.V., CROZE, E., CONSTANTINESCU, S.N., MULLERSMAN, J.E., and PFEFFER, L.M. (1998). The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-Stat activation and receptor down-regulation. Virology 242, 14-21.
-
(1998)
Virology
, vol.242
, pp. 14-21
-
-
Basu, L.1
Yang, C.H.2
Murti, A.3
Garcia, J.V.4
Croze, E.5
Constantinescu, S.N.6
Mullersman, J.E.7
Pfeffer, L.M.8
-
127
-
-
0025669818
-
Treatment of rotavirus infection in neonate and weanling pigs using natural human interferon alpha
-
LECCE, J.G., CUMMINS, J.M., and RICHARDS, A.B. (1990). Treatment of rotavirus infection in neonate and weanling pigs using natural human interferon alpha. J. Mol. Biother. 2, 211-216.
-
(1990)
J. Mol. Biother.
, vol.2
, pp. 211-216
-
-
Lecce, J.G.1
Cummins, J.M.2
Richards, A.B.3
-
128
-
-
0027765747
-
Treatment of fourteen chronic active NBsAg+, HBeAg+ hepatitis patients with low dose natural human interferon alpha administered orally
-
ZIELINSKA, W., PASZKIEWICZ, J., KORCZAK, A., WLASIUK, M., ZOLTOWSKA, A., SZUTOWICZ, A., CUMMINS, J., and GEORGIADES, J. (1993). Treatment of fourteen chronic active NBsAg+, HBeAg+ hepatitis patients with low dose natural human interferon alpha administered orally. Arch. Immunol. Ther. Exp. 43, 241-251.
-
(1993)
Arch. Immunol. Ther. Exp.
, vol.43
, pp. 241-251
-
-
Zielinska, W.1
Paszkiewicz, J.2
Korczak, A.3
Wlasiuk, M.4
Zoltowska, A.5
Szutowicz, A.6
Cummins, J.7
Georgiades, J.8
-
129
-
-
0025011019
-
Low-dose oral administration of human interferon alpha can control the development of Theileria parva infection in cattle
-
YOUNG, A.S., MARITIM, A.C., KARIUKI, D.P., STAGG, D.A., WAFULA, J.M., MUTUGI, J.J., CUMMINS, J.M., RICHARDS, A.B., and BURNS, C. (1990). Low-dose oral administration of human interferon alpha can control the development of Theileria parva infection in cattle. Parasitology 101, 201-209.
-
(1990)
Parasitology
, vol.101
, pp. 201-209
-
-
Young, A.S.1
Maritim, A.C.2
Kariuki, D.P.3
Stagg, D.A.4
Wafula, J.M.5
Mutugi, J.J.6
Cummins, J.M.7
Richards, A.B.8
Burns, C.9
-
130
-
-
0023772551
-
Oral use of human alpha interferon in cats
-
CUMMINS, J.M., TOMPKINS, M.B., OLSEN, R.G., TOMPKINS, W.A., and LEWIS, M.G. (1988). Oral use of human alpha interferon in cats. J. Biol. Response Mod. 7, 513-523.
-
(1988)
J. Biol. Response Mod.
, vol.7
, pp. 513-523
-
-
Cummins, J.M.1
Tompkins, M.B.2
Olsen, R.G.3
Tompkins, W.A.4
Lewis, M.G.5
-
131
-
-
0027717436
-
The effect of low dose oral human interferon alpha therapy on diarrhea in veal calves
-
CUMMINS, J.M., GAWTHROP, J., HUTCHESON, D.P., CUMMINS, M.J., and ZECK, D. (1993). The effect of low dose oral human interferon alpha therapy on diarrhea in veal calves. Arch. Immunol. Ther. Exp. (Warsz.) 41, 199-203.
-
(1993)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.41
, pp. 199-203
-
-
Cummins, J.M.1
Gawthrop, J.2
Hutcheson, D.P.3
Cummins, M.J.4
Zeck, D.5
-
132
-
-
0027732797
-
Oral therapy with human interferon alpha in calves experimentally injected with infectious bovine rhinotracheitis virus
-
CUMMINS, J.M., HUTCHESON, D.P., CUMMINS, M.J., GEORGIADES, J.A., and RICHARDS, A.B. (1993). Oral therapy with human interferon alpha in calves experimentally injected with infectious bovine rhinotracheitis virus. Arch. Immunol. Ther. Exp. (Warsz.) 41, 193-197.
-
(1993)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.41
, pp. 193-197
-
-
Cummins, J.M.1
Hutcheson, D.P.2
Cummins, M.J.3
Georgiades, J.A.4
Richards, A.B.5
-
133
-
-
0029055628
-
Oral treatment of transmissible gastroenteritis with natural human interferon alpha: A field study
-
CUMMINS, J.M., MOCK, R.E., SHIVE, B.W., KRAKOWKA, S., RICHARDS, A.B., and HUTCHESON, D.P. (1995). Oral treatment of transmissible gastroenteritis with natural human interferon alpha: a field study. Vet. Immunol. Immunopathol. 45, 355-360.
-
(1995)
Vet. Immunol. Immunopathol.
, vol.45
, pp. 355-360
-
-
Cummins, J.M.1
Mock, R.E.2
Shive, B.W.3
Krakowka, S.4
Richards, A.B.5
Hutcheson, D.P.6
-
134
-
-
0026561074
-
Low-dose oral natural human interferon-alpha in 29 patients with HIV-1 infection: A double-blind, randomized, placebo-controlled trial
-
KAISER, G., JAEGER, H., BIRKMANN, J., POPPINGER, J., CUMMINS, J., and GALLMEIER, W. (1992). Low-dose oral natural human interferon-alpha in 29 patients with HIV-1 infection: a double-blind, randomized, placebo-controlled trial. AIDS 6, 563-569.
-
(1992)
AIDS
, vol.6
, pp. 563-569
-
-
Kaiser, G.1
Jaeger, H.2
Birkmann, J.3
Poppinger, J.4
Cummins, J.5
Gallmeier, W.6
-
135
-
-
0030803798
-
Low-dose oral type I interferon reduce early virus replication of murine cytomegalovirus in vivo
-
BEILHARZ, M., MACDONALD, W., WATSON, M., HENG, J., McGEACHIE, J., and LAWSON, C. (1997). Low-dose oral type I interferon reduce early virus replication of murine cytomegalovirus in vivo. J. Interferon Cytokine Res. 17, 625-630.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 625-630
-
-
Beilharz, M.1
Macdonald, W.2
Watson, M.3
Heng, J.4
McGeachie, J.5
Lawson, C.6
-
136
-
-
0031670817
-
A pilot double-blind, randomized, and placebo-controlled study of orally administered IFN-alpha-n1 (Ins) in pediatric patients with measles
-
LECCIONES, J.A., ABEJAR, N.H., DIMAANO, E.E., BARTOLOME, R., CINCO, S., MARIANO, N., YERRO, M.E., COBAR, S., and FUGGAN, B. (1998). A pilot double-blind, randomized, and placebo-controlled study of orally administered IFN-alpha-n1 (Ins) in pediatric patients with measles. J. Interferon Cytokine Res. 18, 647-652.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 647-652
-
-
Lecciones, J.A.1
Abejar, N.H.2
Dimaano, E.E.3
Bartolome, R.4
Cinco, S.5
Mariano, N.6
Yerro, M.E.7
Cobar, S.8
Fuggan, B.9
-
137
-
-
0031716564
-
Oral-mucosal administration of IFN-alpha potentiates immune response in mice
-
In Process Citation
-
NAGAO, Y., YAMASHIRO, K., HARA, N., HORISAWA, Y., KATO, K., and UEMURA, A. (1998). Oral-mucosal administration of IFN-alpha potentiates immune response in mice [In Process Citation]. J. Interferon Cytokine Res. 18, 661-666.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 661-666
-
-
Nagao, Y.1
Yamashiro, K.2
Hara, N.3
Horisawa, Y.4
Kato, K.5
Uemura, A.6
-
138
-
-
0032840891
-
Interferon action on avian viruses. I. Oral administration of chicken interferon-alpha ameliorates Newcastle disease
-
MARCUS, P.I., VAN DER HEIDE, L., and SEKELLICK, M.J. (1999). Interferon action on avian viruses. I. Oral administration of chicken interferon-alpha ameliorates Newcastle disease. J. Interferon Cytokine Res. 19, 881-885.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 881-885
-
-
Marcus, P.I.1
Van Der Heide, L.2
Sekellick, M.J.3
-
139
-
-
0033017851
-
Oromucosal interferon therapy: Marked antiviral and antitumor activity
-
TOVEY, M.G., and MAURY, C. (1999). Oromucosal interferon therapy: marked antiviral and antitumor activity. J. Interferon Cytokine Res. 19, 145-155.
-
(1999)
J. Interferon Cytokine Res.
, vol.19
, pp. 145-155
-
-
Tovey, M.G.1
Maury, C.2
-
140
-
-
22244491347
-
Deep-lung delivery of proteins
-
PATTON, J. (1998). Deep-lung delivery of proteins. Modern Drug Deliv. 1, 19-28.
-
(1998)
Modern Drug Deliv.
, vol.1
, pp. 19-28
-
-
Patton, J.1
-
141
-
-
0024407508
-
Pharmacokinetics and toxicity of inhaled human interferon-alpha in patients with lung cancer
-
KINNULA, V., MATTSON, K., and CANTELL, K. (1989). Pharmacokinetics and toxicity of inhaled human interferon-alpha in patients with lung cancer. J. Interferon Res. 9, 419-423.
-
(1989)
J. Interferon Res.
, vol.9
, pp. 419-423
-
-
Kinnula, V.1
Mattson, K.2
Cantell, K.3
-
142
-
-
0027090169
-
Inhaled natural human interferon alpha induces bronchospastic reactions in asthmatics
-
KRASNOWSKA, M., MALOLEPSZY, J., LIEBHART, E., and INGLOT, A.D. (1992). Inhaled natural human interferon alpha induces bronchospastic reactions in asthmatics. Arch. Immunol. Ther. Exp. (Warsz.) 40, 75-78.
-
(1992)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.40
, pp. 75-78
-
-
Krasnowska, M.1
Malolepszy, J.2
Liebhart, E.3
Inglot, A.D.4
-
143
-
-
0029005118
-
Immune tolerance and protection against allergic sensitization
-
HOLT, P.G. (1995). Immune tolerance and protection against allergic sensitization. Allergy, 50, 34-36.
-
(1995)
Allergy
, vol.50
, pp. 34-36
-
-
Holt, P.G.1
-
144
-
-
0030202910
-
Immunoregulation of the allergic reaction in the respiratory tract
-
HOLT, P.G. (1996). Immunoregulation of the allergic reaction in the respiratory tract. Eur. Respir. J. 22(Suppl.), 85s-89s.
-
(1996)
Eur. Respir. J.
, vol.22
, Issue.SUPPL.
-
-
Holt, P.G.1
-
145
-
-
0002519643
-
Delivery of biotherapeutics by inhalation aerosol
-
A.L. Adjei and P.K. Gupta (eds.) New York: Marcel Dekker
-
NIVEN. R. (1997). Delivery of biotherapeutics by inhalation aerosol. In: Inhalation Delivery of Therapeutic Peptides and Proteins. A.L. Adjei and P.K. Gupta (eds.) New York: Marcel Dekker, pp. 151-231.
-
(1997)
Inhalation Delivery of Therapeutic Peptides and Proteins
, pp. 151-231
-
-
Niven, R.1
-
146
-
-
4243546231
-
Safety, tolerability, and pharmacodynamics of a recombinant human interferon beta 1a following oral administration in healthy male volunteers
-
TRINCHARD-LUGAN, I., BUCLIN, T., LAPOINTE, K., SPERTINI, F., BIOLLAZ, J., FRANCIS, G., MUNAFO, A., and YTHIER, A. (2002). Safety, tolerability, and pharmacodynamics of a recombinant human interferon beta 1a following oral administration in healthy male volunteers. Neurology 58, A491.
-
(2002)
Neurology
, vol.58
-
-
Trinchard-Lugan, I.1
Buclin, T.2
Lapointe, K.3
Spertini, F.4
Biollaz, J.5
Francis, G.6
Munafo, A.7
Ythier, A.8
-
147
-
-
0002376956
-
Clinical trial of oral interferon beta 1a (r/beneferon) in relapsing remitting MS
-
POLMAN, C., KAPPOS, L., POZZILLI, C., DAHLKE, F., SANDBRINK, R., and BARKHOF, F. (2001). Clinical trial of oral interferon beta 1a (r/beneferon) in relapsing remitting MS. Mult. Scler. 7(Suppl. 11), S10.
-
(2001)
Mult. Scler.
, vol.7
, Issue.SUPPL. 11
-
-
Polman, C.1
Kappos, L.2
Pozzilli, C.3
Dahlke, F.4
Sandbrink, R.5
Barkhof, F.6
-
148
-
-
0026720880
-
The clinical application of the interferons: A review
-
NSW Therapeutic Assessment Group
-
STUART-HARRIS, R.C., LAUCHLAN, R., and DAY, R. (1992). The clinical application of the interferons: a review. NSW Therapeutic Assessment Group. Med. J. Aust. 156, 869-872.
-
(1992)
Med. J. Aust.
, vol.156
, pp. 869-872
-
-
Stuart-Harris, R.C.1
Lauchlan, R.2
Day, R.3
-
149
-
-
0023099032
-
Clinical overview of alpha interferon. Studies and future directions
-
SPIEGEL, R.J. (1987). Clinical overview of alpha interferon. Studies and future directions. Cancer 59, 626-631.
-
(1987)
Cancer
, vol.59
, pp. 626-631
-
-
Spiegel, R.J.1
-
150
-
-
0026410006
-
The use of interferon-alpha in virus infections
-
FINTER, N.B., CHAPMAN, S., DOWD, P., JOHNSTON, J.M., MANNA, V., SARANTIS, N., SHERON, N., SCOTT, G., PHUA, S., and TATUM, P.B. (1991). The
-
(1991)
Drugs
, vol.42
, pp. 749-765
-
-
Finter, N.B.1
Chapman, S.2
Dowd, P.3
Johnston, J.M.4
Manna, V.5
Sarantis, N.6
Sheron, N.7
Scott, G.8
Phua, S.9
Tatum, P.B.10
-
151
-
-
0036022693
-
Spotlight on peginterferon-alpha-2a (40KD) in chronic hepatitis C
-
PERRY, C.M., and JARVIS, B. (2002). Spotlight on peginterferon-alpha-2a (40KD) in chronic hepatitis C. BioDrugs 16, 213-217.
-
(2002)
BioDrugs
, vol.16
, pp. 213-217
-
-
Perry, C.M.1
Jarvis, B.2
-
152
-
-
0029420586
-
Interferon alpha treatment of relapsing-remitting multiple sclerosis: Long-term study of the correlations between clinical and magnetic resonance imaging results and effects on the immune function
-
DURELLI, L., BONGIOANNI, M.R., CAVALLO, R., FERRERO, B., FERRI, R., VERDUN, E., BRADAC, G.B., RIVA, A., GEUNA, M., BERGAMINI, L., et al. (1995). Interferon alpha treatment of relapsing-remitting multiple sclerosis: long-term study of the correlations between clinical and magnetic resonance imaging results and effects on the immune function. Mult. Scler. 1, S32-37.
-
(1995)
Mult. Scler.
, vol.1
-
-
Durelli, L.1
Bongioanni, M.R.2
Cavallo, R.3
Ferrero, B.4
Ferri, R.5
Verdun, E.6
Bradac, G.B.7
Riva, A.8
Geuna, M.9
Bergamini, L.10
-
153
-
-
0345601517
-
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
-
PRISMS (PREVENTION OF RELAPSES AND DISABILITY BY INTERFERON BETA-1A SUBCUTANEOUSLY IN MULTIPLE SCLEROSIS) STUDY GROUP. (1998). Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet 352, 1498-1504.
-
(1998)
Lancet
, vol.352
, pp. 1498-1504
-
-
-
154
-
-
0034977353
-
Functional classification of interferon-stimulated genes identified using microarrays
-
DE VEER, M.J., HOLKO, M., FREVEL, M., WALKER, E., DER, S., PARANJAPE, J.M., SILVERMAN, R.H., and WILLIAMS, B.R. (2001). Functional classification of interferon-stimulated genes identified using microarrays. J. Leukocyte Biol. 69, 912-920.
-
(2001)
J. Leukocyte Biol.
, vol.69
, pp. 912-920
-
-
De Veer, M.J.1
Holko, M.2
Frevel, M.3
Walker, E.4
Der, S.5
Paranjape, J.M.6
Silverman, R.H.7
Williams, B.R.8
-
155
-
-
0032417696
-
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
-
DER, S.D., ZHOU, A., WILLIAMS, B.R., and SILVERMAN, R.H. (1998). Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc. Natl. Acad. Sci. USA 95, 15623-15628.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.3
Silverman, R.H.4
-
156
-
-
0031771256
-
The evolution of the type I interferons
-
ROBERTS, R.M., LIU, L., GUO, Q., LEAMAN, D., and BIXBY, J. (1998). The evolution of the type I interferons. J. Interferon Cytokine Res. 18, 805-816.
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 805-816
-
-
Roberts, R.M.1
Liu, L.2
Guo, Q.3
Leaman, D.4
Bixby, J.5
-
157
-
-
0029076226
-
The IFN pregnancy recognition hormone IFN-tau blocks both development and super-antigen reactivation of experimental allergic encephalomyelitis without associated toxicity
-
SOOS, J.M., SUBRAMANIAM, P.S., HOBEIKA, A.C., SCHIFFENBAUER, J., and JOHNSON, H.M. (1995). The IFN pregnancy recognition hormone IFN-tau blocks both development and super-antigen reactivation of experimental allergic encephalomyelitis without associated toxicity. J. Immunol. 155, 2747-2753.
-
(1995)
J. Immunol.
, vol.155
, pp. 2747-2753
-
-
Soos, J.M.1
Subramaniam, P.S.2
Hobeika, A.C.3
Schiffenbauer, J.4
Johnson, H.M.5
-
158
-
-
0030894174
-
CD4 T suppressor cells mediate interferon tau protection against experimental allergic encephalomyelitis
-
MUJTABA, M.G., SOOS, J.M., and JOHNSON, H.M. (1997). CD4 T suppressor cells mediate interferon tau protection against experimental allergic encephalomyelitis. J. Neuroimmunol. 75, 35-42.
-
(1997)
J. Neuroimmunol.
, vol.75
, pp. 35-42
-
-
Mujtaba, M.G.1
Soos, J.M.2
Johnson, H.M.3
-
159
-
-
0031456603
-
The antiproliferative and antiviral activities of IFN-tau variants in human cells
-
ALEXENKO, A.P., LEAMAN, D.W., LI, J., and ROBERTS, R.M. (1997). The antiproliferative and antiviral activities of IFN-tau variants in human cells. J. Interferon Cytokine Res. 17, 769-779.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 769-779
-
-
Alexenko, A.P.1
Leaman, D.W.2
Li, J.3
Roberts, R.M.4
-
160
-
-
0029420676
-
Human interferon omega - A review
-
ADOLF, G.R. (1995). Human interferon omega - a review. Mult. Scler. 1(Suppl. 1) S44-47.
-
(1995)
Mult. Scler.
, vol.1
, Issue.SUPPL. 1
-
-
Adolf, G.R.1
|