Long-lasting modification of intrinsic discharge properties in subicular neurons following status epilepticus

European Journal of Neuroscience

Volumn 16, Issue 2, 2002, Pages 259-266

  Wellmer, Jörg ^a   Su, Hailing ^b   Beck, Heinz ^a   Yaari, Yoel ^b  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Epilepsy; Intrinsic bursting; Pilocarpine model; Rat; Subiculum

Indexed keywords

CALCIUM ION; DIAZEPAM; PILOCARPINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DEPOLARIZATION; EPILEPTIC STATE; EPILEPTOGENESIS; MALE; NERVE CELL; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SUBICULUM;

ACTION POTENTIALS; ANIMALS; ANTICONVULSANTS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL MEMBRANE; DIAZEPAM; EPILEPSY, TEMPORAL LOBE; HIPPOCAMPUS; MALE; MUSCARINIC AGONISTS; NEURAL PATHWAYS; NEURONAL PLASTICITY; PILOCARPINE; PYRAMIDAL CELLS; RATS; RATS, WISTAR; STATUS EPILEPTICUS; SYNAPTIC TRANSMISSION; TIME FACTORS;

EID: 0036974231     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.02086.x     Document Type: Article

References (43)

1. Andrew, R.D., Fagan, M., Ballyk, B.A. & Rosen, A.S. (1989) Seizure susceptibility and the osmotic state. Brain Res., 498, 175-180.
2. Aram, J.A. & Lodge, D. (1987) Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate. Neurosci. Lett., 83, 345-350.
3. Azouz, R., Alroy, G. & Yaari, Y. (1997) Modulation of endogenous firing patterns by osmolarity in rat hippocampal neurones. J. Physiol. (Lond.), 502, 175-187.
4. Azouz, R., Jensen, M.S. & Yaari, Y. (1996) Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. J. Physiol. (Lond.), 492, 211-223.
5. Behr, J., Empson, R.M., Schmitz, D., Gloveli, T. & Heinemann, U. (1996) Electrophysiological properties of rat subicular neurons in vitro. Neurosci. Lett., 220, 41-44.
6. Behr, J., Empson, R.M., Schmitz, D., Gloveli, T. & Heinemann, U. (1997) Effects of serotonin on synaptic and intrinsic properties of rat subicular neurons in vitro. Brain Res., 773, 217-222.
7. Ben Ari, Y. (2001) Cell death and synaptic reorganizations produced by seizures. Epilepsia, 42 (Suppl. 3), 5-7.
8. Cavalheiro, E.A., Leite, J.P., Bortolotto, Z.A., Turski, W.A., Ikonomidou, C. & Turski, L. (1991) Long-term effects of pilocarpine in rats: Structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia, 32, 778-782.
9. 2+ blockade of synaptically activated N-methyl-D-aspartate receptor-channels in CA1 pyramidal neurons in kainic acid-lesioned rat hippocampus. Neuroscience, 88, 727-739.
10. Church, J. & Baimbridge, K.G. (1991) Exposure to high-pH medium increases the incidence and extent of dye coupling between rat hippocampal CA1 pyramidal neurons in vitro. J. Neurosci., 11, 3289-3295.
11. Cossart, R., Dinocourt, C., Hirsch, J.C., Merchan-Perez, A., De Felipe, J., Ben Ari, Y., Esclapez, M. & Bernard, C. (2001) Dendritic but not somatic GABAergic inhibition is decreased in experimental epilepsy. Nature Neurosci., 4, 52-62.
12. Coulter, D.A. & DeLorenzo, R.J. (1999) Basic mechanisms of status epilepticus. Adv. Neurol., 79, 725-733.
13. Covolan, L. & Mello, L.E. (2000) Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus. Epilepsy Res., 39, 133-152.
14. Finch, D.M. & Babb, T.L. (1981) Demonstration of caudally directed hippocampal efferents in the rat by intracellular injection of horseradish peroxidase. Brain Res., 214, 405-410.
15. Fountain, N.B. (2000) Status epilepticus: risk factors and complications. Epilepsia, 41 (Suppl. 2), S23-S30.
16. Franceschetti, S., Buzio, S., Sancini, G., Panzica, F. & Avanzini, G. (1993) Expression of intrinsic bursting properties in neurons of maturing sensorimotor cortex. Neurosci. Lett., 162, 25-28.
17. Franceschetti, S., Sancini, G., Panzica, F., Radici, C. & Avanzini, G. (1998) Postnatal differentiation of firing properties and morphological characteristics in layer V pyramidal neurons of the sensorimotor cortex. Neuroscience, 83, 1013-1024.
18. Gastaut, H. (1983) Classification of status epilepticus. In Delgado-Escueta, A.V., Wasterlain, C.G., Treiman, D.M. & Porter, R.J. (eds), Advances in Neurology. Raven Press, New York, pp. 15-35.
19. A receptor function in dentate granule and CA1 neurons. J. Neurophysiol., 77, 1924-1938.
20. Heinemann, U., Franceschetti, S., Hamon, B., Konnerth, A. & Yaari, Y. (1985) Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices. Brain Res., 325, 349-352.
21. Jefferys, J.G.R. & Haas, H.L. (1982) Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission. Nature, 300, 448-450.
22. Jensen, M.S., Azouz, R. & Yaari, Y. (1994) Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium. J. Neurophysiol., 71, 831-839.
23. Jensen, M.S., Azouz, R. & Yaari, Y. (1996) Spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. J. Physiol. (Lond.), 492, 199-210.
24. Jensen, M.S. & Yaari, Y. (1997) Role of intrinsic burst-firing, potassium accumulation, and electrical coupling in the elevated potassium model of hippocampal epilepsy. J. Neurophysiol., 77, 1224-1233.
25. Jung, H.H., Staff, N.P. & Spruston, N. (2001) Action potential bursting in subicular pyramidal neurons is driven by a calcium tail current. J. Neurosci., 21, 3312-3321.
26. Lothman, E.W., Rempe, D.A. & Mangan, P.S. (1995) Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol., 74, 841-848.
27. Madison, D.V. & Nicoll, R.A. (1984) Control of repetitive discharge of rat CA1 pyramidal neurones in vitro. J. Physiol. (Lond.), 354, 319-331.
28. Mangan, P.S., Rempe, D.A. & Lothman, E.W. (1995) Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol., 74, 829-840.
29. Mattia, D., Hwa, G.G. & Avoli, M. (1993) Membrane properties of rat subicular neurons in vitro. J. Neurophysiol., 70, 1244-1248.
30. Mattia, D., Kawasaki, H. & Avoli, M. (1997a) In vitro electrophysiology of rat subicular bursting neurons. Hippocampus, 7, 48-57.
31. Mattia, D., Kawasaki, H. & Avoli, M. (1997b) Repetitive firing and oscillatory activity of pyramidal-like bursting neurons in the rat subiculum. Exp. Brain Res., 114, 507-517.
32. 2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. J. Physiol. (Lond.), 532, 205-216.
33. Sloviter, R.S. (1999) Status epilepticus-induced neuronal injury and network reorganization. Epilepsia, 40 (Suppl. 1), S34-S39.
34. Staff, N.P., Jung, H.Y., Thiagarajan, T., Yao, M. & Spruston, N. (2000) Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus. J. Neurophysiol., 84, 2398-2408.
35. Su, H., Alroy, G., Kirson, E.D. & Yaari, Y. (2001) Extracellular calcium modulates persistent sodium current-dependent intrinsic bursting in rat hippocampal neurons. J. Neurosci., 21, 4173-4182.
36. Sutula, T., Cascino, G., Cavazos, J., Parada, I. & Ramirez, L. (1989) Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann. Neurol., 26, 321-330.
37. Traub, R.D. & Wong, R.K. (1982) Cellular mechanism of neuronal synchronization in epilepsy. Science, 216, 745-747.
38. Traynelis, S.F. & Dingledine, R. (1989) Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures. J. Neurophysiol., 61, 927-938.
39. Turner, D.A. & Wheal, H.V. (1991) Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons. J. Neurosci., 11, 2786-2794.
40. Van Groen, T. & Wyss, J.M. (1990) The connections of presubiculum and parasubiculum in the rat. Brain Res., 518, 227-243.
41. Wong, R.K. & Prince, D.A. (1981) Afterpotential generation in hippocampal pyramidal cells. J. Neurophysiol., 45, 86-97.
42. Yaari, Y. & Beck, H. (2002) 'Epileptic Neurons' in temporal lobe epilepsy. Brain Pathol., in press.
43. Yaari, Y., Konnerth, A. & Heinemann, U. (1983) Spontaneous epileptiform activity of CA1 hippocampal neurons in low extracellular calcium solutions. Exp. Brain Res., 51, 153-156.