In vitro inhibition of [3H]-angiotensin II binding on the human AT1 receptor by proanthocyanidins from Guazuma ulmifolia bark

Planta Medica

Volumn 68, Issue 12, 2002, Pages 1066-1071

  Caballero George, Catherina ^a   Vanderheyden, Patrick M L ^b   De Bruyne, Tess ^a   Shahat, Abdel Atty ^a   Van Den Heuvel, Hilde ^a   Solis, Pablo N ^c   Gupta, Mahabir P ^c   Claeys, Magda ^a   Pieters, Luc ^a   Vauquelin, Georges ^b   Vlietinck, Arnold J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c UNIVERSIDAD DE PANAMÁ   (Panama)

Author keywords

AT1 receptor; CHO cells; Guazurna ulmifolia; Proanthocyanidins; Radioligand binding; Sterculiaceae

Indexed keywords

ACETONE; ANGIOTENSIN 2 RECEPTOR; EPICATECHIN; GUAZUMA ULMIFOLIA EXTRACT; PLANT EXTRACT; PROANTHOCYANIDIN DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; ANTHOCYANIN; PROANTHOCYANIDIN; TRITIUM;

ANIMAL CELL; ARTICLE; BARK; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FRACTIONATION; IN VITRO STUDY; NONHUMAN; POLYMERIZATION; ANGIOSPERM; BINDING COMPETITION; BINDING SITE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; HUMAN; METABOLISM;

ANIMALIA; GUAZUMA; GUAZUMA ULMIFOLIA; MALVACEAE;

ANGIOTENSIN II; ANTHOCYANINS; BINDING SITES; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALVACEAE; PLANT BARK; PLANT EXTRACTS; PROANTHOCYANIDINS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; TRITIUM;

EID: 0036967140     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-36344     Document Type: Article

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