메뉴 건너뛰기




Volumn 52, Issue 3, 2002, Pages 204-213

Antisense oligodeoxynucleotides against thrombomodulin suppress the cell growth of lung adenocarcinoma cell line A549

Author keywords

A549 cells; Antisense oligodeoxynucleotides; Cell growth; Lung adenocarcinoma; Thrombomodulin

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; IDOXURIDINE; THROMBOMODULIN;

EID: 0036964701     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2002.01332.x     Document Type: Article
Times cited : (11)

References (42)
  • 1
    • 0020063793 scopus 로고
    • Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein
    • Esmon NL, Owen WG, Esmon CT. Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C.J. Biol. Chem.1982;257: 859-864.
    • (1982) C.J. Biol. Chem. , vol.257 , pp. 859-864
    • Esmon, N.L.1    Owen, W.G.2    Esmon, C.T.3
  • 2
    • 0023374585 scopus 로고
    • Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation
    • Suzuki K, Kusumoto H, Deyashiki Y et al. Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J. 1987;6: 1891-1897.
    • (1987) EMBO J. , vol.6 , pp. 1891-1897
    • Suzuki, K.1    Kusumoto, H.2    Deyashiki, Y.3
  • 3
    • 0345173854 scopus 로고
    • Human thrombomodulin gene is intron depleted: Nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control
    • Jackman RW, Beeler DL, Fritze L, Soff G, Rosenberg RD. Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control. Proc. Natl Acad. Sci. USA 1987;84: 6425-6429.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6425-6429
    • Jackman, R.W.1    Beeler, D.L.2    Fritze, L.3    Soff, G.4    Rosenberg, R.D.5
  • 4
    • 0034732094 scopus 로고    scopus 로고
    • Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex
    • Fuentes-Prior P, Iwanaga Y, Huber R et al. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex.Nature 2000;404: 518-525.
    • (2000) Nature , vol.404 , pp. 518-525
    • Fuentes-Prior, P.1    Iwanaga, Y.2    Huber, R.3
  • 5
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon CT. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J. Biol. Chem. 1989; 264: 4743-4746.
    • (1989) J. Biol. Chem. , vol.264 , pp. 4743-4746
    • Esmon, C.T.1
  • 6
    • 0019332589 scopus 로고
    • Regulation of activated protein C by a new protein. A possible function for bovine protein S
    • Walker FJ. Regulation of activated protein C by a new protein. A possible function for bovine protein S. J. Biol. Chem. 1980; 255: 5521-5524.
    • (1980) J. Biol. Chem. , vol.255 , pp. 5521-5524
    • Walker, F.J.1
  • 7
    • 0021344553 scopus 로고
    • Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V
    • Fulcher CA, Gardiner JE, Griffin JH, Zimmerman TS. Pro-teolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V.Blood 1984;63: 486-489.
    • (1984) Blood , vol.63 , pp. 486-489
    • Fulcher, C.A.1    Gardiner, J.E.2    Griffin, J.H.3    Zimmerman, T.S.4
  • 8
    • 0023763075 scopus 로고
    • Functionally active thrombomodulin is present in human platelets
    • Suzuki K, Nishioka J, Hayashi T, Kosaka Y. Functionally active thrombomodulin is present in human platelets. J. Biochem. (Tokyo) 1988;104: 628-632.
    • (1988) J. Biochem. (Tokyo) , vol.104 , pp. 628-632
    • Suzuki, K.1    Nishioka, J.2    Hayashi, T.3    Kosaka, Y.4
  • 9
    • 0025134925 scopus 로고
    • Localization and biosynthesis of functional thrombomodulin in human megakaryocytes and a human megakaryoblastic cell line (MEG-01)
    • Ogura M, Ito T, Maruyama I et al. Localization and biosynthesis of functional thrombomodulin in human megakaryocytes and a human megakaryoblastic cell line (MEG-01). Thromb. Haemost. 1990;64: 297-301.
    • (1990) Thromb. Haemost. , vol.64 , pp. 297-301
    • Ogura, M.1    Ito, T.2    Maruyama, I.3
  • 10
    • 0026328854 scopus 로고
    • Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages
    • McCachren SS, Diggs J, Weinberg JB, Dittman WA. Thrombo-modulin expression by human blood monocytes and by human synovial tissue lining macrophages. Blood 1991; 78: 3128-3132.
    • (1991) Blood , vol.78 , pp. 3128-3132
    • McCachren, S.S.1    Diggs, J.2    Weinberg, J.B.3    Dittman, W.A.4
  • 11
    • 0031106293 scopus 로고    scopus 로고
    • Novel expression and localization of active thrombomodulin on the surface of mouse brain astrocytes
    • Pindon A, Hantai D, Jandrot-Perrus M, Festoff BW. Novel expression and localization of active thrombomodulin on the surface of mouse brain astrocytes.Glia 1997;19: 259-268.
    • (1997) Glia , vol.19 , pp. 259-268
    • Pindon, A.1    Hantai, D.2    Jandrot-Perrus, M.3    Festoff, B.W.4
  • 12
    • 0028258643 scopus 로고
    • Thrombomodulin expression by human keratinocytes. Induction of cofactor activity during epidermal differentiation
    • Raife TJ, Lager DJ, Madison KC et al. Thrombomodulin expression by human keratinocytes. Induction of cofactor activity during epidermal differentiation.J. Clin. Invest. 1994;93: 1846-1851.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1846-1851
    • Raife, T.J.1    Lager, D.J.2    Madison, K.C.3
  • 13
    • 0029911905 scopus 로고    scopus 로고
    • Expression patterns of adhesion receptors in the developing mouse lung: Functional implications
    • Buck CA, Edelman JM, Buck CE, Kennedy G, Baldwin HS. Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes. Commun. 1996;4: 69-87.
    • (1996) Cell Adhes. Commun. , vol.4 , pp. 69-87
    • Buck, C.A.1    Edelman, J.M.2    Buck, C.E.3    Kennedy, G.4    Baldwin, H.S.5
  • 14
    • 0026693694 scopus 로고
    • Thrombomodulin expression in malignant pleural mesothelioma and pulmonary adenocarcinoma
    • Collins CL, Ordonez NG, Schaefer R et al. Thrombomodulin expression in malignant pleural mesothelioma and pulmonary adenocarcinoma.Am. J. Pathol. 1992;141: 827-833.
    • (1992) Am. J. Pathol. , vol.141 , pp. 827-833
    • Collins, C.L.1    Ordonez, N.G.2    Schaefer, R.3
  • 15
    • 0023280047 scopus 로고
    • Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin
    • Yonezawa S, Maruyama I, Sakae K, Igata A, Majerus PW, Sato E. Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin.Am. J. Clin. Pathol. 1987;88: 405-411.
    • (1987) Am. J. Clin. Pathol. , vol.88 , pp. 405-411
    • Yonezawa, S.1    Maruyama, I.2    Sakae, K.3    Igata, A.4    Majerus, P.W.5    Sato, E.6
  • 16
    • 20244383576 scopus 로고
    • Expression of thrombomodulin in esophageal squamous cell carcinoma and its relationship to lymph node metastasis
    • Tezuka Y, Yonezawa S, Maruyama I et al. Expression of throm-bomodulin in esophageal squamous cell carcinoma and its relationship to lymph node metastasis.Cancer Res. 1995;55: 4196-4200.
    • (1995) Cancer Res. , vol.55 , pp. 4196-4200
    • Tezuka, Y.1    Yonezawa, S.2    Maruyama, I.3
  • 17
    • 0033984451 scopus 로고    scopus 로고
    • Expression of thrombomodulin in squamous cell carcinoma of the lung: Its relationship to lymph node metastasis and prognosis of the patients
    • Ogawa H, Yonezawa S, Maruyama I et al. Expression of throm-bomodulin in squamous cell carcinoma of the lung: its relationship to lymph node metastasis and prognosis of the patients. Cancer Lett. 2000;149: 95-103.
    • (2000) Cancer Lett. , vol.149 , pp. 95-103
    • Ogawa, H.1    Yonezawa, S.2    Maruyama, I.3
  • 20
    • 0028876697 scopus 로고
    • Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
    • Healy AM, Rayburn HB, Rosenberg RD, Weiler H. Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system.Proc. Natl Acad. Sci. USA 1995;92: 850-854.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 850-854
    • Healy, A.M.1    Rayburn, H.B.2    Rosenberg, R.D.3    Weiler, H.4
  • 21
    • 0000686636 scopus 로고    scopus 로고
    • Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity
    • Zhang Y, Weiler-Guettler H, Chen J et al. Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity.J. Clin. Invest. 1998;101: 1301-1309.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1301-1309
    • Zhang, Y.1    Weiler-Guettler, H.2    Chen, J.3
  • 22
    • 0030737726 scopus 로고    scopus 로고
    • Value of thrombomodulin immunostaining in the diagnosis of mesothelioma
    • Ordonez NG. Value of thrombomodulin immunostaining in the diagnosis of mesothelioma. Histopathology 1997; 31: 25-30.
    • (1997) Histopathology , vol.31 , pp. 25-30
    • Ordonez, N.G.1
  • 23
    • 0030969332 scopus 로고    scopus 로고
    • Expression and localization of thrombomodulin in preneoplastic bronchial lesions and in lung cancer
    • Tolnay E, Wiethege T, Muller KM. Expression and localization of thrombomodulin in preneoplastic bronchial lesions and in lung cancer.Virchows Arch. 1997;430: 209-212.
    • (1997) Virchows Arch. , vol.430 , pp. 209-212
    • Tolnay, E.1    Wiethege, T.2    Muller, K.M.3
  • 24
    • 0022371596 scopus 로고
    • The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin
    • Maruyama I, Majerus PW. The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin. J. Biol. Chem. 1985; 260: 15432-15438.
    • (1985) J. Biol. Chem. , vol.260 , pp. 15432-15438
    • Maruyama, I.1    Majerus, P.W.2
  • 25
    • 0017367571 scopus 로고
    • Cell line A549: A model system for the study of alveolar type II cell function
    • Smith BT. Cell line A549: a model system for the study of alveolar type II cell function. Am. Rev. Respir. Dis 1977;115: 285-293.
    • (1977) Am. Rev. Respir. Dis. , vol.115 , pp. 285-293
    • Smith, B.T.1
  • 26
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews DH, Sabina J, Zuker M, Turner DH. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure.J. Mol. Biol. 1999;288: 911-940.
    • (1999) J. Mol. Biol. , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 27
    • 0002287019 scopus 로고    scopus 로고
    • Algorithms and thermodynamics for RNA secondary structure prediction: A practical guide
    • Barciszewski J, Clark BFC, eds. Dordrecht, The Netherlands: Kluwer Academic Publishers
    • Zuker M, Mathews DH, Turner DH. Algorithms and thermodynamics for RNA secondary structure prediction: A practical guide. In: Barciszewski J, Clark BFC, eds. RNA Biochemistry and Biotechnology. Dordrecht, The Netherlands: Kluwer Academic Publishers, 1999: 11-43.
    • (1999) RNA Biochemistry and Biotechnology , pp. 11-43
    • Zuker, M.1    Mathews, D.H.2    Turner, D.H.3
  • 28
    • 0030200460 scopus 로고    scopus 로고
    • Application of a combination of neutral red and amido black staining for rapid, reliable cytotoxicity testing of biomaterials
    • Ciapetti G, Granchi D, Verri E, Savarino L, Cavedagna D, Pizzoferrato A. Application of a combination of neutral red and amido black staining for rapid, reliable cytotoxicity testing of biomaterials.Biomaterials 1996;17: 1259-1264.
    • (1996) Biomaterials , vol.17 , pp. 1259-1264
    • Ciapetti, G.1    Granchi, D.2    Verri, E.3    Savarino, L.4    Cavedagna, D.5    Pizzoferrato, A.6
  • 29
    • 0030801002 scopus 로고    scopus 로고
    • PSI-BLAST: A new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA et al. PSI-BLAST: a new generation of protein database search programs. Nucl. Acids Res. 1997;25: 3389-3402.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3
  • 30
    • 0029939761 scopus 로고    scopus 로고
    • Surface thrombomodulin modulates thrombin receptor responses on vascular smooth muscle cells
    • Grinnell BW, Berg DT. Surface thrombomodulin modulates thrombin receptor responses on vascular smooth muscle cells. Am. J. Physiol. 1996;270: H603-H609.
    • (1996) Am. J. Physiol. , vol.270
    • Grinnell, B.W.1    Berg, D.T.2
  • 31
    • 0033789547 scopus 로고    scopus 로고
    • Recombinant thrombomodulin inhibits arterial smooth muscle cell proliferation induced by thrombin
    • Li J, Garnette CS, Cahn M et al. Recombinant thrombomodulin inhibits arterial smooth muscle cell proliferation induced by thrombin.J. Vasc. Surg. 2000;32: 804-813.
    • (2000) J. Vasc. Surg. , vol.32 , pp. 804-813
    • Li, J.1    Garnette, C.S.2    Cahn, M.3
  • 32
    • 0032523739 scopus 로고    scopus 로고
    • A subcloned human esophageal squamous cell carcinoma cell line with low thrombomodulin expression showed increased invasiveness compared with a high thrombomodulin-expressing clone - Thrombomodulin as a possible candidate for an adhesion molecule of squamous cell carcinoma
    • Matsushita Y, Yoshiie K, Imamura Y et al. A subcloned human esophageal squamous cell carcinoma cell line with low thrombomodulin expression showed increased invasiveness compared with a high thrombomodulin-expressing clone -thrombomodulin as a possible candidate for an adhesion molecule of squamous cell carcinoma. Cancer Lett. 1998;127: 195-201.
    • (1998) Cancer Lett. , vol.127 , pp. 195-201
    • Matsushita, Y.1    Yoshiie, K.2    Imamura, Y.3
  • 33
    • 0028064867 scopus 로고
    • Heat shock of vascular endothelial cells induces an up-regulatory transcriptional response of the thrombomodulin gene that is delayed in onset and does not attenuate
    • Conway EM, Liu L, Nowakowski B, Steiner-Mosonyi M, Jackman RW. Heat shock of vascular endothelial cells induces an up-regulatory transcriptional response of the thrombomodulin gene that is delayed in onset and does not attenuate. J. Biol. Chem. 1994;269: 22804-22810.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22804-22810
    • Conway, E.M.1    Liu, L.2    Nowakowski, B.3    Steiner-Mosonyi, M.4    Jackman, R.W.5
  • 34
    • 0028292792 scopus 로고
    • Characterization of thrombomodulin expression in response to retinoic acid and identification of a retinoic acid response element in the human thrombomodulin gene
    • Dittman WA, Nelson SC, Greer PK, Horton ET, Palomba ML, McCachren SS. Characterization of thrombomodulin expression in response to retinoic acid and identification of a retinoic acid response element in the human thrombomodulin gene.J. Biol. Chem. 1994;269: 16925-16932.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16925-16932
    • Dittman, W.A.1    Nelson, S.C.2    Greer, P.K.3    Horton, E.T.4    Palomba, M.L.5    McCachren, S.S.6
  • 35
    • 0023089665 scopus 로고
    • Endotoxin enhances tissue factor and suppresses thrombo-modulin expression of human vascular endothelium in vitro
    • Moore KL, Andreoli SP, Esmon NL, Esmon CT, Bang NU. Endotoxin enhances tissue factor and suppresses thrombo-modulin expression of human vascular endothelium in vitro.J. Clin. Invest. 1987;79: 124-130.
    • (1987) J. Clin. Invest. , vol.79 , pp. 124-130
    • Moore, K.L.1    Andreoli, S.P.2    Esmon, N.L.3    Esmon, C.T.4    Bang, N.U.5
  • 36
    • 0023755932 scopus 로고
    • Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells
    • Conway EM, Rosenberg RD. Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells. Mol. Cell Biol. 1988;8: 5588-5592.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 5588-5592
    • Conway, E.M.1    Rosenberg, R.D.2
  • 37
    • 0025755359 scopus 로고
    • Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells in vitro
    • Hirokawa K, Aoki N. Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells in vitro. J. Cell Physiol. 1991;147: 157-165.
    • (1991) J. Cell Physiol. , vol.147 , pp. 157-165
    • Hirokawa, K.1    Aoki, N.2
  • 38
    • 0029069178 scopus 로고
    • Transforming growth factor beta 1 and beta 2 induce down-modulation of thrombomodulin in human umbilical vein endothelial cells
    • Ohji T, Urano H, Shirahata A et al. Transforming growth factor beta 1 and beta 2 induce down-modulation of thrombomodulin in human umbilical vein endothelial cells. Thromb. Haemost. 1995;73: 812-818.
    • (1995) Thromb. Haemost. , vol.73 , pp. 812-818
    • Ohji, T.1    Urano, H.2    Shirahata, A.3
  • 39
    • 0021747118 scopus 로고
    • Differential phosphorylation events associated with phorbol ester effects on acceleration versus inhibition of cell growth
    • Feuerstein N, Sahai A, Anderson WB, Salomon DS, Cooper HL. Differential phosphorylation events associated with phorbol ester effects on acceleration versus inhibition of cell growth. Cancer Res. 1984;44: 5227-5233.
    • (1984) Cancer Res. , vol.44 , pp. 5227-5233
    • Feuerstein, N.1    Sahai, A.2    Anderson, W.B.3    Salomon, D.S.4    Cooper, H.L.5
  • 40
    • 0023623241 scopus 로고
    • TGF-beta inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression
    • Takehara K, LeRoy EC, Grotendorst GR. TGF-beta inhibition of endothelial cell proliferation: alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression.Cell 1987;49: 415-422.
    • (1987) Cell , vol.49 , pp. 415-422
    • Takehara, K.1    LeRoy, E.C.2    Grotendorst, G.R.3
  • 41
    • 0035853404 scopus 로고    scopus 로고
    • Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells
    • Olivot JM, Estebanell E, Lafay M, Brohard B, Aiach M, Rendu F. Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells.Circ. Res. 2001;88: 681-687.
    • (2001) Circ. Res. , vol.88 , pp. 681-687
    • Olivot, J.M.1    Estebanell, E.2    Lafay, M.3    Brohard, B.4    Aiach, M.5    Rendu, F.6
  • 42
    • 0035253672 scopus 로고    scopus 로고
    • Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression
    • Assoian RK, Schwartz MA. Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression.Curr. Opin. Genet. Dev. 2001;11: 48-53.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 48-53
    • Assoian, R.K.1    Schwartz, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.