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Volumn 19, Issue 3, 2002, Pages 391-397

Variable expression and hypermethylation of p16 gene in patients with T-ALL and cell lines

Author keywords

Acute lymphoblastic leukemia (ALL); Expression; Methylation; p16; Tumor suppressor gene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; PROTEIN P15; PROTEIN P16;

EID: 0036964171     PISSN: 13007777     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (26)
  • 1
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • Hirama T, Koeffler HP. Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood 1995;86:841-54.
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, H.P.2
  • 2
    • 0029132295 scopus 로고
    • Alterations of cyclin-dependent kinase 4 inhibitor (p16INK4A/MTSI) gene structure and expression in acute lymphoblastic leukemias
    • Delmer A, Tang R, Senamaud-Beaufort C, Paterlini P, Brechot C, Zittoun R. Alterations of cyclin-dependent kinase 4 inhibitor (p16INK4A/MTSI) gene structure and expression in acute lymphoblastic leukemias. Leukemia 1995;9:1240-5.
    • (1995) Leukemia , vol.9 , pp. 1240-1245
    • Delmer, A.1    Tang, R.2    Senamaud-Beaufort, C.3    Paterlini, P.4    Brechot, C.5    Zittoun, R.6
  • 3
    • 0001208875 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells
    • Wang QM, Lones JB, Studzinski GP. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. Cancer Res 1996;56:264-7.
    • (1996) Cancer Res , vol.56 , pp. 264-267
    • Wang, Q.M.1    Lones, J.B.2    Studzinski, G.P.3
  • 6
    • 0027769876 scopus 로고
    • New regulatory motif in cellcycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach DA. New regulatory motif in cellcycle control causing specific inhibition of cyclin D/CDK4. Nature 1993;366:704.
    • (1993) Nature , vol.366 , pp. 704
    • Serrano, M.1    Hannon, G.J.2    Beach, D.A.3
  • 11
    • 0344993959 scopus 로고    scopus 로고
    • Hereditary TP53 codon 292 and somatic P16(INK4A) codon 94 mutations in a Li-Fraumeni syndrome family
    • Guran S, Tunca Y, Imirzalioglu N. Hereditary TP53 codon 292 and somatic P16(INK4A) codon 94 mutations in a Li-Fraumeni syndrome family. Cancer Genet Cytogenet 1999;113:145-51.
    • (1999) Cancer Genet Cytogenet , vol.113 , pp. 145-151
    • Guran, S.1    Tunca, Y.2    Imirzalioglu, N.3
  • 12
    • 0023742620 scopus 로고
    • Cytogenetic analysis of melanocytes from premalignant nevi and melanomas
    • Cowan JM, Halaban R, Francke U. Cytogenetic analysis of melanocytes from premalignant nevi and melanomas. J Nat Cancer Inst 1988;80:1159-64.
    • (1988) J Nat Cancer Inst , vol.80 , pp. 1159-1164
    • Cowan, J.M.1    Halaban, R.2    Francke, U.3
  • 13
    • 0028845142 scopus 로고
    • Inactivation of the CDK2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in ALL common human cancer
    • Herman JG, Merlo a, Mao LI, et al. Inactivation of the CDK2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in ALL common human cancer. Cancer Res 1995;55:4525-30.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.I.3
  • 14
    • 0031860559 scopus 로고    scopus 로고
    • Review of alterations of the cyclin-dependent kinase inhibited INK4 family gene p16, p15, p18 and p19 in human leukemia and lymphoma cells
    • Drexler HG. Review of alterations of the cyclin-dependent kinase inhibited INK4 family gene p16, p15, p18 and p19 in human leukemia and lymphoma cells. Leukemia 1998;12:845-59.
    • (1998) Leukemia , vol.12 , pp. 845-859
    • Drexler, H.G.1
  • 17
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, Ngung T, Beart RW, Tornout JMV, Jones PA. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Research 1995;55:4531-5.
    • (1995) Cancer Research , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Ngung, T.4    Beart, R.W.5    Tornout, J.M.V.6    Jones, P.A.7
  • 18
    • 0029967152 scopus 로고    scopus 로고
    • Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatid condensation
    • Costello JF, Berger M, Huang HS, Cavenee WK. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatid condensation. Cancer Research 1996;56:2405-10.
    • (1996) Cancer Research , vol.56 , pp. 2405-2410
    • Costello, J.F.1    Berger, M.2    Huang, H.S.3    Cavenee, W.K.4
  • 19
    • 0029011539 scopus 로고
    • 5-prime CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D. 5-prime CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature Med 1995;1:686-92.
    • (1995) Nature Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 20
    • 0033991683 scopus 로고    scopus 로고
    • Hypermethylation of p16 and p15 gene and RD protein expression in acute leukemia
    • Guo SX, Taki T, Ohnishi H, et al. Hypermethylation of p16 and p15 gene and RD protein expression in acute leukemia. Leuk Res 2000;24:39-46.
    • (2000) Leuk Res , vol.24 , pp. 39-46
    • Guo, S.X.1    Taki, T.2    Ohnishi, H.3
  • 21
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTSI gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JPJ, Davidson NE, Sidrnsky D, Baylin SB. Inactivation of the CDKN2/p16/MTSI gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-30.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.J.5    Davidson, N.E.6    Sidrnsky, D.7    Baylin, S.B.8
  • 22
    • 0029134873 scopus 로고
    • Homozygous deletions of the CDKN2(MTSI/p16 INK4) gene in cell lines established from children with acute lymphoblastic leukemia
    • Zhou M, Gu L, James CD, He J, Yeager AM, Smith SD, Findley HW. Homozygous deletions of the CDKN2(MTSI/p16 INK4) gene in cell lines established from children with acute lymphoblastic leukemia. Leukemia 1995;9:1159.
    • (1995) Leukemia , vol.9 , pp. 1159
    • Zhou, M.1    Gu, L.2    James, C.D.3    He, J.4    Yeager, A.M.5    Smith, S.D.6    Findley, H.W.7
  • 23
    • 0012736311 scopus 로고    scopus 로고
    • Preferential inactivation of p15INK4B but not p16INK4A by hypermethylation in T-cell acute lymphoblastic leukemia
    • Yu AL, Batova A, Diccianni MB, Pullent J, Link MP, Yu J. Preferential inactivation of p15INK4B but not p16INK4A by hypermethylation in T-cell acute lymphoblastic leukemia. ASH Meeting 1996;1408.
    • (1996) ASH Meeting , pp. 1408
    • Yu, A.L.1    Batova, A.2    Diccianni, M.B.3    Pullent, J.4    Link, M.P.5    Yu, J.6
  • 24
    • 0035300727 scopus 로고    scopus 로고
    • Methylation of p15 and p16 genes in acute promyelocytic leukemia: Potential diagnostic and prognostic significance
    • Chim CS, Liang R, Tam CY, Kwong YL. Methylation of p15 and p16 genes in acute promyelocytic leukemia: Potential diagnostic and prognostic significance. J Clin Oncol 2001;19:2033-40.
    • (2001) J Clin Oncol , vol.19 , pp. 2033-2040
    • Chim, C.S.1    Liang, R.2    Tam, C.Y.3    Kwong, Y.L.4
  • 26
    • 0028172926 scopus 로고
    • Absence of p16 INK4 is restricted to the subset of lung cancer lines that retains wild type RB
    • Otterson GA, Kratzke A, Conox A, Kim YW, Kaye FJ. Absence of p16 INK4 is restricted to the subset of lung cancer lines that retains wild type RB. Oncogene 1994;9:3375.
    • (1994) Oncogene , vol.9 , pp. 3375
    • Otterson, G.A.1    Kratzke, A.2    Conox, A.3    Kim, Y.W.4    Kaye, F.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.