Intracellular diacylglycerol accumulation induced by doxorubicin in rat hepatocytes: Potential involvement of phospholipases C and D

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 52-56

  Martínez, Rosa ^a   Navarro, Rosaura ^a   Martín, César ^a   Aurrekoetxea, Igor ^a   Hernández, M Luisa ^a   Lacort, Mercedes ^a   Ruiz Sanz, José Ignacio ^a   Ruiz Larrea, M Begoña ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Diacylglycerol; Doxorubicin; Phospholipases C and D; Rat hepatocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALCOHOL DERIVATIVE; DIACYLGLYCEROL; DOXORUBICIN; GLUTATHIONE; PHOSPHOLIPASE C; PHOSPHOLIPASE D;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; LIVER CELL; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALIA;

EID: 0036962403     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04605.x     Document Type: Conference Paper

References (5)

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2. 2+-ATPase by Adriamycin in intact human erythrocytes. Arch. Biochem. Biophys. 321: 459-466.
3. BETTAÏEB, A. et al. 1999. Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis. Mol. Pharmacol. 55: 118-125.
4. KAISER, E., P. CHIBA & K. ZAKY. 1990. Phospholipases in biology and medicine. Clin. Biochem. 23: 349-370.
5. MARTÍN, A. et al. 1993. Decreased activities of phosphatidate phosphohydrolase and phospholipase D in ras and tyrosine kinase (fps) transformed fibroblasts. J. Biol. Chem. 268: 23924-23932.