Expression of adrenomedullin and its receptor in lungs of rats with hypoxic pulmonary hypertension

Chinese Medical Journal

Volumn 115, Issue 12, 2002, Pages 1806-1808

  Cheng, Deyun ^a   Tian, Wei ^a   Chen, Wenbin ^a   Xiao, Xinrong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Adrenomedullin; Hypertension; Hypoxia; Pulmonary; Receptor; Reverse transcription polymerase chain reaction

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; BETA ACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CONTROLLED STUDY; HEART CATHETERIZATION; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOXIA; IMAGE ANALYSIS; LUNG ARTERY PRESSURE; LUNG PARENCHYMA; MALE; NONHUMAN; PULMONARY HYPERTENSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS;

ADRENOMEDULLIN; ANIMALS; ANOXIA; ARTERIOLES; GENE EXPRESSION; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; LUNG; MALE; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, PEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0036958633     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Kitamura, K, Kangawa K, Kawamoto M, et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophy Res Common 1993; 192: 553-560.
2. Vijay P, Szekely L, Sharp TG, et al. Adrenomedullin in patients at high risk for pulmonary hypertension. Ann Thorac Surg 1998; 66:500-505.
3. Zhao L, Brown LA, Owji AA, et al. Adrenomedullin activity in chronically hypoxic rat lungs. Am J Physiol 1996;271:H622-H629.
4. Martinez A, Miller MJ, Unsworth EJ, et al. Expression of adrenomedullin in normal human lung and in pulmonary tumors. Endocrinology 1995;136:4099-4105.