Colchicine myopathy: A vacuolar myopathy with selective type I muscle fiber involvement. An immunohistochemical and electron microscopic study of two cases

Acta Neuropathologica

Volumn 103, Issue 2, 2002, Pages 100-106

  Fernandez, Carla ^a   Figarella Branger, D ^a   Alla, P ^b   Harle J R ^c   Pellisier, J F ^a  

^a TIMONE HOSPITAL   (France)

^b Military Teaching Hospital Sainte Anne   (France)

^c HÔPITAL DE LA CONCEPTION   (France)

Author keywords

Colchicine; Immunuhistochemistry; Mictrotubes; Myopathy

Indexed keywords

ACID PHOSPHATASE; AMIODARONE; ANTIBODY; BETA CRYSTALLIN; CIPROFIBRATE; COLCHICINE; CORTICOSTEROID; DYSTROPHIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEROSIN; TUBULIN;

AGED; ARTICLE; CASE REPORT; CELL MEMBRANE; CELL ULTRASTRUCTURE; CELL VACUOLE; CHRONIC KIDNEY FAILURE; COMPLEMENT ACTIVATION; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; ELECTRON MICROSCOPY; EXTRACELLULAR SPACE; FEMALE; GOUT; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY AMYLOIDOSIS; LYSOSOME; MALE; MICROTUBULE; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE FIBRIL; MUSCLE WEAKNESS; MYALGIA; MYOPATHY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SARCOPLASM;

AGED; AGED, 80 AND OVER; COLCHICINE; FEMALE; GOUT SUPPRESSANTS; HUMANS; MALE; MICROSCOPY, ELECTRON; MUSCULAR DISEASES; VACUOLES;

EID: 0036944594     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010100434     Document Type: Article

References (31)

1. Aplin A, Jasionowski T, Tuttle DL, Lenk SE, Dunn WA (1992) Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles. J Cell Physiol 152:458-466
2. Arai H, Atomi Y (1997) Chaperone activity of alpha B-crystallin suppresses tubulin aggregation through complex formation. Cell Struct Funct 22:539-544
3. Bluhm WF, Martin JL, Mestril R, Dillmann WH (1998) Specific heat shock proteins protect microtubules during stimulated ischemia in cardiac myocytes. Am J Physiol 275:H2243-2249
4. Boudriau S, Vincent M, Côté CH, Rogers PA (1993) Cytoskeletal structure of skeletal muscle: identification of an intricate exosarcomeric microtubule lattice in slow- and fast-twitch muscle fibers. J Histochem Cytochem 41:1013-1021
5. Dawson TM, Starkebaum G (1997) Colchicine induced rhabdomyolysis. J Rheumatol 24:2045-2046
6. De Almeida JB, Stow JL (1991) Disruption of microtubules alters polarity of basement membrane proteoglycan secretion in epithelial cells. Am J Physiol 260:C691-700
7. De Bleecker JL, Engel AG, Winkelmann JC (1993) Localization of dystrophin and β-spectrin in vacuolar myopathies. Am J Pathol 143:1200-1208
8. De Deyn PP, Ceuterick C, Saxena V, Crols R, Chappel R, Martin J (1995) Chronic colchicine-induced myopathy and neuropathy. Acta Neurol Belg 95:29-32
9. Elkjaer ML, Birn H, Agre P, Christensen EI, Nielsen S (1995) Effects of microtubule disruption on endocytosis, membrane recycling and distribution of Aquaporin-1 and gp330 in proximal tubule cells. Eur J Cell Biol 67:57-72
10. O Ellinger A, Pavelka M (1984) Colchicine-induced tubular, vesicular and cisternal organelle aggregates in absorptive cells of the small intestine of the rat. I. Morphology and phosphatase cytochemistry. Biol Cell 52:43-52
11. Ellinger A, Pavelka M (1986) Colchicine-induced tubular, vesicular and cisternal organelle aggregates in absorptive cells of the small intestine of the rat. II. Endocytosis studies. Biol Cell 58:31-42
12. Fengsrud M, Roos N, Berg T, Liou W, Slot JW, Seglen PO (1995) Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuoles distributions. Exp Cell Res 221:504-519
13. Gruberg L, Har-Zahav Y, Agranat O, Freimark D (1999) Acute myopathy induced by colchicine in a cyclosporine treated heart transplant recipient: possible role of the multidrug resistance transporter. Transplant Proc 31:2157-2158
14. Himmelmann F, Schroder JM (1992) Colchicine myopathy in a case of familial Mediterranean fever: immunohistochemical and ultrastructural study of accumulated tubulin-immunoreactive material. Acta Neuropathol 83:440-444
15. Hirsimäki Y, Arstila AU, Trump BF (1975) Autophagocytosis: in vitro induction by microtubule poisons. Exp Cell Res 92: 11-14
16. Kaisto T, Rahkila P, Marjomäki V, Parton RG, Metsikkö K (1999) Endocytosis in skeletal muscle fibers. Exp Cell Res 253:551-560
17. Kato K, Ito H, Inaguma Y, Okamoto K, Saga S (1996) Synthesis and accumulation of αB-crystallin in C6 glioma cells is induced by agents that promote the disassembly of microtubules. J Biol Chem 271:26989-26994
18. Kontos HA (1962) Myopathy associated with colchicines toxicity. N Engl J Med 266:38-39
19. Kuncl RW, Duncan G, Watson D, Alderson K, Rogawski MA, Peper M (1987) Colchicine myopathy and neuropathy. N Engl J Med 316:1562-1568
20. Louboutin JP, Villanova M, Lucas-Heron B, Fardeau M (1997) X-linked vacuolar myopathy: membrane attack complex deposition on muscle fiber membranes with calcium accumulation on sarcolemma. Ann Neurol 41:117-120
21. Markand ON, D'Agostino AN (1971) Ultrastructural changes in skeletal muscle induced by colchicine. Arch Neurol 24: 72-82
22. Neefjies JJ, Momburg F (1993) Cell biology of antigen presentation. Curr Opin Immunol 5:27-34
23. Nickerson SC, Smith JJ, Keenan TW (1980) Role of microtubules in milk secretion - Action of colchicine on microtubules and exocytosis of secretory vesicles in rat mammary epithelial cells. Cell Tissue Res 207:361-376
24. Pavelka M, Ellinger A (1983) Effect of colchicine on the Golgi complex of rat pancreatic acinar cells. J Cell Biol 97:737-748
25. Punnonen EL, Reunanen H (1990) Effects of vinblastine, leucine and 3-methyladenine on autophagy in Ehrlich ascites cells. Exp Mol Pathol 52:87-97
26. Rahkila P, Väänänen K, Saraste J, Metsikkö K (1997) Endoplasmic reticulum to Golgi trafficking in multinucleated skeletal muscle fibers. Exp Cell Res 234:452-464
27. Redman CM, Banerjee D, Manning C, Huang CY, Green K (1978) In vivo effect of colchicine on hepatic protein systhesis and on the conversion of proalbumin to serum albumin. J Cell Biol 77:400-416
28. Riggs JE, Schochet SS, Gutmann L, Crosby TW, DiBartolomeo A (1986) Chronic human colchicine neuropathy and myopathy. Arch Neurol 43:521-523
29. Robbins E, Gonatas NK (1964) Histochemical and ultrastructural studies on HeLa cell cultures exposed to spindle inhibitors with special reference to the interphase cell. J Histochem Cytochem 12:704-711
30. Rutkove SB, De Girolami U, Preston DC, Freeman R, Nardin RA, Gouras GK, Donald RJ, Raynor EM (1996) Myotonia in colchicine myoneuropathy. Muscle Nerve 19:870-875
31. Skoufias DA, Scholey JM (1993) Cytoplasmic microtubule-based motor proteins. Curr Opin Cell Biol 5:95-104