Synthesis of 18F labelled FK960, a candidate anti-dementia drug, and PET studies in conscious monkeys

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 45, Issue 14, 2002, Pages 1219-1228

  Murakami, Yoshihiro ^a,c   Nishimura, Shintaro ^a   Noda, Akihiro ^a   Harada, Norihiro ^b   Tsukada, Hideo ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b CENTRAL RESEARCH LABORATORY   (Japan)

^c Medical and Pharmacological Research Center Foundation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN;

DRUG CANDIDATES; HIGHER YIELD; IN-VIVO; LABELINGS; NUCLEOPHILIC FLUORINATION; ONE POT; REACTION SEQUENCES; SPECIFIC ACTIVITY; TRIFLATES; VIVO STUDIES;

NEURODEGENERATIVE DISEASES;

4 NITROBENZOIC ACID ETHYL ESTER; AMMONIUM DERIVATIVE; BENZOIC ACID DERIVATIVE; ETHYL 4 TRIMETHYLAMMONIUM TRIFLATE; N (4 ACETYL 1 PIPERAZINYL) 4 FLUOROBENZAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOMATION; BODY WEIGHT; BRAIN REGION; CONSCIOUSNESS; CONTROLLED STUDY; DEMENTIA; DEVICE; DRUG SYNTHESIS; FLUORINATION; IN VIVO STUDY; ISOTOPE LABELING; MONKEY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY;

EID: 0036943655     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.633     Document Type: Article

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