Exploring the potential of the monobody scaffold: Effects of loop elongation on the stability of a fibronectin type III domain

Protein Engineering

Volumn 15, Issue 12, 2002, Pages 1015-1020

  Batori, Vincent ^a   Koide, Akiko ^a,b   Koide, Shohei ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Antibody mimic; Combinatorial library; Ligand binding; Peptide display; Protein stability

Indexed keywords

FIBRONECTIN; GLYCINE; IMMUNOGLOBULIN;

ARTICLE; BETA SHEET; BINDING SITE; COMBINATORIAL CHEMISTRY; ENTROPY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN STABILITY;

EID: 0036940153     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/15.12.1015     Document Type: Article

References (36)

1. Barbas, C.F., III, Kang, A.S., Lerner, R.A. and Benkovic, S.J. (1991) Proc. Natl Acad. Sci. USA, 88, 7978-7982.
2. Carr, P.A., Erickson, H.P. and Palmer, A.G.R. (1997) Structure, 5, 949-959.
3. Cattaneo, A. and Biocca, S. (1999) Trends Biotechnol., 17, 115-121.
4. Chan, H.S. and Dill, K.A. (1988) J. Chem. Phys., 90, 492-509.
5. Cota, E. and Clarke, J. (2000) Protein Sci., 9, 112-120.
6. Cota, E., Hamill, S.J., Fowler, S.B. and Clarke, J. (2000) J. Mol. Biol., 302, 713-725.
7. Cota, E., Steward, A., Fowler, S.B. and Clarke, J. (2001) J. Mol. Biol., 305, 1185-1194.
8. Delaglio, F., Grzesiek, S., Vuister, G.W., Zhu, G., Pfeifer, J. and Bax, A. (1995) J. Biomol. NMR, 6, 277-293.
9. de Vos, A.M., Ultsch, M. and Kossiakoff, A.A. (1992) Science, 255, 306-312.
10. Dickinson, C.D., Veerapandian, B., Dai, X.-P., Hamlin, R.C., Xuong, N.-H., Ruoslahti, E. and Ely, K.R. (1994) J. Mol. Biol., 236, 1079-1092.
11. Hanes, J. and Pluckthun, A. (1997) Proc. Natl Acad. Sci. USA, 94, 4937-4942.
12. Helms, L.R. and Wetzel, R. (1995) Protein Sci., 4, 2073-2081.
13. Hutchinson, E.G. and Thornton, J.M. (1996) Protein Sci., 5, 212-220.
14. Johnson, B.A. and Blevins, R.A. (1994) J. Biomol. NMR, 4, 603-614.
15. Kay, L.E., Keifer, P. and Saarinen, T. (1992) J. Am. Chem. Soc., 114, 10663-10665.
16. Koide, A., Bailey, C.W., Huang, X. and Koide, S. (1998) J. Mol. Biol., 284, 1141-1151.
17. Koide, S., Bu, Z., Risal, D., Pham, T.-N., Nakagawa, T., Tamura, A. and Engelman, D.M. (1999) Biochemistry, 38, 4757-4767.
18. Koide, A., Jordan, M.R., Horner, S.R., Batori, V. and Koide, S. (2001) Biochemistry, 40, 10326-10333.
19. Koide, A., Abbatiello, S., Rothgery, L. and Koide, S. (2002) Proc., Natl Acad. Sci. USA, 99, 1253-1258.
20. Kraulis, P. (1991) J. Appl. Crystallogr., 24, 946-950.
21. Ladumer, A.G. and Fersht, A.R. (1997) J. Mol. Biol., 273, 330-337.
22. Leahy, D.J., Erickson, H.P., Aukhil, I., Joshi, P. and Hendrickson, W.A. (1994) Proteins: Struct. Funct. Genet., 19, 48-54.
23. Leahy, D.J., Aukhil, I. and Erickson, H.P. (1996) Cell, 84, 155-164.
24. Main, A.L., Harvey, T.S., Baron, M., Boyd, J. and Campbell, I.D. (1992) Cell, 71, 671-678.
25. McConnell, S.J. and Hoess, R.H. (1995) J. Mol. Biol., 250, 460-470.
26. Nagi, A.D. and Regan, L. (1997) Fold. Des., 2, 67-75.
27. Nygren, P.-Å. and Uhlén, M. (1997) Curr. Opin. Struct. Biol., 7, 463-469.
28. O'Neil, K.T. and Hoess, R.H. (1995) Curr. Opin. Struct. Biol., 5, 443-449.
29. Pace, C.N. and Sholtz, J.M. (1997) In Creighton, T.E. (ed.), Protein Structure. A Practical Approach. 2nd edn. IRL Press, Oxford, pp. 299-321.
30. Plaxco, K.W., Spitzfaden, C., Campbell, I.D. and Dobson, C.M. (1997) J. Mol. Biol., 270, 763-770.
31. Press, W.H., Flannery, B.P., Teukolsky, S.A. and Vetterling, W.T. (1992) Numerical Recipes in C. Cambridge University Press, New York.
32. Rader, C., Cheresh, D.A. and Barbas, C.F., 3rd (1998) Proc. Natl Acad. Sci. USA, 95, 8910-8915.
33. Santoro, M.M. and Bolen, D.W. (1992) Biochemistry, 31, 4901-4907.
34. Sieber, V., Pluckthun, A. and Schmid, F.X. (1998) Nature Biotechnol., 16, 955-960.
35. Skerra, A. (2001) J. Biotechnol., 74, 257-275.
36. Smith, C.K., Bu, Z., Anderson, K.S., Sturtevant, J.M., Engelman, D.M. and Regan, L. (1996) Protein Sci., 5, 2009-2019.