GDNF family signalling in exocrine tissues: Distinct roles for GDNF and neurturin in parasympathetic neuron development

Advances in Experimental Medicine and Biology

Volumn 506 A, Issue , 2002, Pages 19-26

  Rossi, Jari ^a   Airaksinen, Matti S ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEURTURIN; PROTEIN RET;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL MIGRATION; CELL PROLIFERATION; CELL SIZE; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EXOCRINE CELL; INTESTINE INNERVATION; MOUSE; NERVE CELL DIFFERENTIATION; NEWBORN; NONHUMAN; PARASYMPATHETIC GANGLION; PARASYMPATHETIC INNERVATION; PARASYMPATHETIC NERVE CELL; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0036936622     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0717-8_2     Document Type: Conference Paper

References (23)

1. M.S. Airaksinen, A. Titievsky, and M. Saarma, GDNF family neurotrophic factor signaling: four masters, one servant?, Mol. Cell. Neurosci. 13:313 (1999).
2. R.H. Baloh, H. Enomoto, E.M.J. Johnson, and J. Milbrandt, The GDNF family ligands and receptors - implications for neural development, Curr. Opin. Neurobiol. 10:103 (2000).
3. M. Saarma. GDNF - a stranger in the TGF-β superfamily?. Eur. J. Biochem. 267:6968 (2000).
4. A. Schuchardt, V. D'Agati, L. Larsson-Blomberg, F. Costantini, and V. Pachnis. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret, Nature 367:380 (1994).
5. M.W. Moore, R.D. Klein, I. Farinas, H. Sauer, M. Armanini, H. Phillips, L.F. Reichardt, A.M. Ryan, K. Carver-Moore, and A. Rosenthal, Renal and neuronal abnormalities in mice lacking GDNF, Nature 382:76 (1996).
6. J.G. Pichel, L. Shen, H.Z. Sheng, A.C. Granholm, J. Drago, A. Grinberg, E.J. Lee, S.P. Huang, M. Saarma, B.J. Hoffer, H. Sariola, and H. Westphal, Defects in enteric innervation and kidney development in mice lacking GDNF, Nature 382:73 (1996).
7. M.P. Sánchez, I. Silos-Santiago, J. Frisen, B. He, S.A. Lira, and M. Barbacid, Renal agenesis and the absence of enteric neurons in mice lacking GDNF, Nature 382:70 (1996).
8. G. Cacalano, I. Farinas, L.-C. Wang, K. Hagler, A. Forgie, M. Moore, M. Armanini, et al., GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney, Neuron 21:53 (1998).
9. H. Enomoto, T. Araki, A. Jackman, R.O. Heuckeroth, W.D. Snider, E.M.J. Johnson, and J. Milbrandt, GFRα1-deficient mice have deficits in the enteric nervous system and kidneys, Neuron 21:317 (1998).
10. X. Meng, M. Lindahl, M.E. Hyvonen, M. Parvinen, D.G. de Rooij, M.W. Hess, A. Raatikainen-Ahokas, K. Sainio, H. Rauvala, M. Lakso, J.G. Pichel, H. Westphal, M. Saarma, and H. Sariola, Regulation of cell fate decision of undifferentiated spermatogonia by GDNF, Science 287:1489 (2000).
11. R.O. Heuckeroth, H. Enomoto, J.R. Grider, J.P. Golden, J.A. Hanke, A. Jackman, D.C. Molliver, M.E. Bardgett, W.D. Snider, E.M.J. Johnson, and J. Milbrandt, Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons, Neuron 22:253 (1999).
12. J. Rossi, K. Luukko, D. Poteryaev, A. Laurikainen, Y.-F. Sun, T. Laakso, S. Eerikäinen, R. Tuominen, M. Lakso, H. Rauvala, U. Arumäe, M. Saarma, and M.S. Airaksinen, Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFRα2, a functional neurturin receptor, Neuron 22:243 (1999).
13. J. Rossi, A. Tomac, M. Saarma, and M.S. Airaksinen, Distinct roles for GFRα1 and GFRα2 signalling in different cranial parasympathetic ganglia in vivo, Eur. J, Neurosci 12:3944 (2000).
14. H. Enomoto, R.O. Heuckeroth, J.P. Golden, E.M. Johnson, and J. Milbrandt, Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin, Development 127:4877 (2000).
15. C. Marcos and V. Pachnis, The effect of the ret- mutation on the normal development of the central and parasympathetic nervous systems, Int. J. Dev. Biol, Suppl 1:137S (1996).
16. R.D. Heathcote and P.B. Sargent, Growth and morphogenesis of an autonomic ganglion. I. Matching neurons with target, J. Neurosci. 7:2493 (1987).
17. T.L. Deckwerth, J.L. Elliott, C.M. Knudson, E.M.J. Johnson, W.D. Snider, and S.J. Korsmeyer, BAX is required for neuronal death after trophic factor deprivation and during development, Neuron 17:401 (1996).
18. K. Kawa and S. Roper, On the two subdivisions and intrinsic synaptic connexions in the submandibular ganglion of the rat, J Physiol (Lond) 346:301 (1984).
19. J.O. Hiltunen, A. Laurikainen, M.S. Airaksinen, and M. Saarma, GDNF family receptors in the embryonic and postnatal rat heart and reduced cholinergic innervation in mice hearts lacking ret or GFRα2, Dev Dyn 219:28 (2000).
20. A. Laurikainen, J.O. Hiltunen, J. Thomas-Crusells, S. Vanhatalo, U. Arumäe, M.S. Airaksinen, E. Klinge, and M. Saarma, Neurturin is a neurotrophic factor for penile parasympathetic neurons in adult rat, J. Neurobiol. 43:198 (2000).
21. T. Tsuzuki, M. Takahashi, N. Asai, T. Iwashita, M. Matsuyama, and J. Asai, Spatial and temporal expression of the ret proto-oncogene product in embryonic, infant and adult rat tissues, Oncogene 10:191 (1995).
22. M.G. Tansey, R.H. Baloh, J. Milbrandt, and E.M.J. Johnson, GFRα-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival, Neuron 25:611 (2000).
23. S. Eketjäll, M. Fainzilber, J. Murray-Rust, and C.F. Ibanez, Distinct structural elements in GDNF mediate binding to GFRα1 and activation of the GFRα1-c-Ret receptor complex, EMBO J 18:5901 (1999).