Radioprotective role of Amaranthus gangeticus Linn.: A biochemical study on mouse brain

Journal of Medicinal Food

Volumn 5, Issue 4, 2002, Pages 189-195

  Verma, Rajesh Kumar ^a   Sisodia, R ^a   Bhatia, A L ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; ALPHA CAROTENE; ALPHA TOCOPHEROL; AMARANTHUS GANGETICUS EXTRACT; ASCORBIC ACID; BETA CAROTENE; FOLIC ACID; PLANT EXTRACT; RETINOL; UNCLASSIFIED DRUG;

AMARANTHUS GANGETICUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN METABOLISM; BRAIN TISSUE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG ISOLATION; IONIZING RADIATION; LIPID PEROXIDATION; MEDICINAL PLANT; MOUSE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLANT LEAF; PRIORITY JOURNAL; PROTEIN CONTENT; RADIATION EXPOSURE; RADIATION PROTECTION;

AMARANTHUS; AMARANTHUS TRICOLOR; ANIMALIA; MURINAE;

EID: 0036934011     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/109662002763003339     Document Type: Article

References (26)

1. Bhattacharya SK, Satyam K, Ghosal S: Antioxidant activity of glycowithanolides from Withania somnifera. Indian J Exp Biol 1996;35:236-239.
2. Yen Grow-Chin, She Chig W, Pin-der D: Extraction and identification of components from the level of mulberry. J Agric Food Chem 1996;44:1687-1690.
3. Bhatia AL: The anti-aging role of vitamin A and β-carotene. Indian J Gerontol 1998;12:70-79.
4. Chandha SL: Natural source of antioxidant and their adequacy in diet to prevent atherosclerosis. Mediquest 1997;14:337-351.
5. Gerster H: Anticarcinogenic effect of common carotenoids. Int J Vitam Nutr Res 1993;6:93-121.
6. Gey K: The relationship of antioxidant status and the risk of cancer and cardiovascular disease: A critical evaluation of observational data. In: Free Radicals in the Environment, Medicine and Toxicology, (Nohl H, Esterbauer H, Rice-Evans C, eds.). Richelieu Press, London, 1994, pp. 181-219.
7. Blot WJ, Li JY, Taylor PR, Guo W, Dawsey SM, Li B: The Linxial trials: Mortality rates by vitamin-mineral intervention group. Am J Clin Nutr 1995;62[Suppl]: 1424s-1426s.
8. Hochstein P, Atallah AS: The nature of oxidants and antioxidant systems in the inhibition of mutation and cancer. Mutat Res 1988;202:363-375.
9. Ramesh S, Manda K, Bhatia AL: Protective effect of β-carotene on radiation induced lipid peroxidation. Curr Sci 1997;73:470-471.
10. Bhatia AL, Manda K: Role of β-carotene against radiation induced lipid-peroxidation in mice testis. Res J Chem Environ 2000;1:59-61.
11. Seifter E, Rettura G, Padawer J, Stratford F, Weinzweig J, Demetriou AA, Levenson SM: Morbidity and mortality reduction by supplemental vitamin A or β-carotene in CBA mice given total-body γ-radiation. J Natl Cancer Inst 1984;73:1167-1177.
12. Mills EED: The modifying effect of beta-carotene on radiation and chemotherapy induced oral mucositis. Br J Cancer 1988;57:416-417.
13. Mathews-Roth MM: Recent progress in the medical application of carotenoids. Pure Appl Chem 1991;63: 147-156.
14. van het Hof KH, Tijburg LB, Pietrzik K, Weststrate JA: Influence of feeding different vegetables on plasma levels of carotenoids, folate and vitamin C. Effect of disruption of the vegetable matrix. Br J Nutr 1999;82:203-212.
15. Leyko W, Bartosz G: Membrane effect of ionizing radiation and hyperthermia. Int J Radiat Biol 1986;49: 743-770.
16. Kale RK, Sitaswad SL: Radiation induced lipid peroxidation in liposomes. Radiat Phys Chem 1990;36: 361-364.
17. Girotti AW: Mechanisms of lipid peroxidation. J Free Radic Biol Med 1985;1:87-95.
18. Esterbauer H, Zollner H, Schaur RJ: Hydroxyalkenals: Cytotoxic products of lipid peroxidation. ISI Atlas of Science Biochem 1988;1:311-317.
19. El-Habit OH, Saada HN, Azab KS, Abdel-Rahman M, El-Malah DF: The modifying effect of beta-carotene on gamma-radiation induced elevation of oxidative reactions and genotoxicity in male rats. Mutat Res 2000;466:179-186.
20. Bacq ZM, Alexander P: Fundamentals of Radiobiology. Pergamon Press, New York, 1961.
21. Grant GA: Mechanism of action of aminothiol radioprotectors. In: Radiation Damage and Sulfhydryl Compounds. IAEA, Vienna, 1969, p. 95.
22. Zhang P, Omaye ST: β-carotene and protein oxidation: Effects of ascorbic acid and alpha-tocopherol. Toxicology 2000;146:37-47.
23. Verma RK, Sisodia R, Bhatia AL: Radioprotective role of Amaranthus gangeticus Linn.: A biochemical study on mice brain: In: Proceedings Conference on Radiobiological Protection of Patients in Medical Application of Ionizing Radiation, ICRPP-2K2, 2002, pp. 161-162.
24. Wender M, Zgorzalewicz: Activation of amino acids following parental x-irradiation in the developing rabbit brain. Folia Biol (Krakow) 1970;18:343-351.
25. Kim SH, Kim JH, Djordjevic B: Effects of x-irradiation on RNA and protein synthesis in HeLa cells. Radiat Res 1970;42:577-589.
26. Saini PP, Nandchahal K, Bhatia AL: Radioprotective role of Amaranthus gangeticus Linn.: A study on haematological constituents in Swiss albino mice. In: Proceedings Conference on Radiobiological Protection of Patients in Medical Application of Ionizing Radiation, ICRPP-2K2, 2002, pp. 163-164.