Interleukin-2 inhibits proliferation of HPV-associated tumor cells and halts tumor growth in vivo

Biochemical and Biophysical Research Communications

Volumn 299, Issue 5, 2002, Pages 818-824

  Casana, Patricia H ^b   Hernandez, Hector ^a   Arana, Manuel J ^a  

^a CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

^b Center of Pharmaceutical Chemistry Cuba   (Cuba)

Author keywords

Human papillomavirus type 16; Interleukin 2; Interleukin 2 receptor; Tumor growth inhibition

Indexed keywords

INTERLEUKIN 2; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL LINE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; INOCULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR; TUMOR CELL; TUMOR GROWTH; TUMOR IMMUNITY; UTERINE CERVIX CARCINOMA; WART VIRUS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; MICE; MICE, INBRED BALB C; NEOPLASMS, EXPERIMENTAL; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-2; RNA, MESSENGER; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS;

ANIMALIA; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPES; PAPILLOMAVIRUS;

EID: 0036926559     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02715-8     Document Type: Article

References (35)

1. F.X. Bosch, M.M. Manos, N. Munoz, M.E. Sherman, A.M. Jansen, J. Peto, M.H. Shiffman, V. Moreno, R.J. Kurman, K.V. Shah, Human papillomavirus in cervical cancer: A worldwide perspective. International biological study on cervical cancer (IBSCC) study group, J. Natl. Cancer Inst. 87 (1995) 796-802.
2. J.M. Walboomers, M.V. Jacobs, M.M. Manos, F.X. Bosch, J.A. Kummer, K.V. Shah, P.J. Snijders, J. Peto, C.J. Meijer, N. Muñoz, Human papillomavirus is a necessary cause of invasive cervical cancer worldwide, J. Pathol. 189 (1999) 12-19.
3. C.S. Herrington, Do HPV-negative cervical carcinomas exist? J. Pathol. 189 (1999) 1-3.
4. M.S. Piver, Handbook of Gynecological Oncology, Little, Brown, Boston, 1996, 369 p.
5. K. Nasiell, V. Roger, M. Nasiell, Behavior of mild cervical dysplasia during long-term follow-up, Obstet. Gynecol. 67 (1986) 665-669.
6. V. Shamanin, M. Glover, C. Rausch, C. Proby, I.M. Leigh, H. zurHausen, E.M. de Villiers, Specific types of human papillomavirus found in benign proliferations and carcinomas of the skin in immunosuppressed patients, Cancer Res. 54 (1994) 4610-4613.
7. K.A. Smith, Interleukin 2, Annu. Rev. Immunol. 2 (1984) 319-333.
8. S.A. Rosenberg, A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone, J. Natl. Cancer Inst. 75 (1985) 595-603.
9. T.L. Whiteside, R.B. Herberman, The role of natural killer cells in immune surveillance of cancer, Curr. Opin. Immunol. 7 (1995) 704-710.
10. W.C. Lin, S. Yasumura, Y. Suminami, M.W. Sung, S. Nagashima, J. Stanson, T.L. Whiteside, Constitutive production of IL-2 by human carcinoma cells, expression of IL-2 receptor, and tumor cell growth, J. Immunol. 155 (1995) 4805-4816.
11. C. Ciacci, Y.R. Mahida, A. Dignass, M. Koizumi, D.K. Podolsky, Functional interleukin-2 receptors on intestinal epithelial cells, J. Clin. Invest. 92 (1993) 527-532.
12. T.E. Reichert, Y. Kashii, J. Stanson, A. Zeevi, T.L. Whiteside, The role of endogenous interleukin-2 in proliferation of human carcinoma cell lines, Br. J. Cancer 81 (1999) 822-831.
13. G.P. Murphy, W.J. Lawrence, R.E. Lenhard, Basis for major current therapies for cancer, in: American Cancer Society Textbook of Clinical Oncology, Atlanta, 1995, pp. 96-129.
14. W.H. West, K.W. Tauer, J.R. Yannelli, G.D. Marshall, D.W. Orr, G.B. Thurman, R.K. Oldham, Constant-infusion recombinant interleukin-2 in adoptive immunotherapy of advanced cancer, N. Engl. J. Med. 316 (1987) 898-905.
15. E.R. Fearon, D.M. Pardoll, T. Itaya, P. Golumbek, H.I. Levitsky, J.W. Simons, H. Karasuyama, B. Vogelstein, P. Frost, Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response, Cell 60 (1990) 397-403.
16. E. Weidmann, M. Sacchi, S. Plaisance, D.S. Hoe, S. Yasumura, W. Lin, J.T. Johnson, R.B. Herberman, B. Azzarone, T.L. Whiteside, Receptors for Interleukin 2 on human squamous carcinoma cell lines and tumor in situ, Cancer Res. 52 (1992) 5963-5970.
17. P. Hernandez, N. Merino, O. LopezOcejo, M.J. Arana, A mouse fibroblast cell model to study human papillomavirus-associated tumorigenesis, Biochem. Biophys. Res. Commun. 270 (2000) 119-124.
18. D.S. Heo, J.G. Park, K. Hata, R. Day, R.B. Heberman, T.L. Whiteside, Evaluation of tetrazolium-based semi-automatic colorimetric assay for measurements of antitumor effects, Cancer Res. 50 (1990) 3681-3690.
19. P. Chomczynski, N. Sacchi, Single step method of RNA isolation by acid guanidinium-thiocyanate-phenol-chloroform extraction, Anal. Biochem. 162 (1987) 156-159.
20. U.K. Hanisch, S.A. Lyons, M. Prinz, C. Nolte, J.R. Weber, H. Kettenmann, F. Kirchhoff, Mouse brain microglia express interleukin-15 and its multimeric receptor complex functionally coupled to Janus kinase activity, J. Biol. Chem. 272 (1997) 28853-28860.
21. S.L. Reiner, S. Zheng, D.B. Corry, R.M. Locksley, Constructing polycompetitor cDNAs for quantitative PCR, J. Immunol. Methods 165 (1993) 37-46.
22. J.L. Arbiser, M.A. Moses, C.A. Fernandez, N. Ghiso, Y. Cao, N. Klauber, D. Frank, M. Brownlee, E. Flynn, S. Parangi, H.R. Byers, J. Folkman, Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways, Proc. Natl. Acad. Sci. USA 94 (1997) 861-866.
23. T.A. Waldmann, C.K. Goldman, R.J. Robb, J.M. Depper, W.J. Leonard, S.O. Sharrow, K.F. Bongiovanni, S.J. Korsmeyer, W.C. Greene, Expression of interleukin 2 receptors on activated human B cells, J. Exp. Med. 160 (1984) 1450-1466.
24. S. Yasumura, W.C. Lin, E. Weidmann, P. Hebda, T.L. Whiteside, Expression of interleukin 2 receptors on human carcinoma cell lines and tumor growth inhibition by interleukin 2, Int. J. Cancer 59 (1994) 225-234.
25. T. Takeshita, H. Asao, K. Ohtani, N. Ishii, S. Kumaki, N. Tanaka, H. Munakata, M. Nakamura, K. Sugamura, Cloning of the γ chain of the human IL-2 receptor, Science 257 (1992) 379-382.
26. K.H. Grabstein, J. Eisenman, K. Shanebeck, C. Rauch, S. Srinivasan, V. Fung, C. Beers, J. Richardson, M.A. Schoenborn, M. Ahdieh, Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor, Science 264 (1994) 965-968.
27. M. Kondo, T. Takeshita, N. Ishii, M. Nakamura, S. Watanabe, K. Arai, K. Sugamura, Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4, Science 262 (1993) 1874-1877.
28. S.M. Russell, A.D. Keegan, N. Harada, Y. Nakamura, M. Noguchi, P. Leland, M.C. Friedmann, A. Miyajima, R.K. Puri, W.E. Paul, Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor, Science 262 (1993) 1880-1883.
29. M. Noguchi, Y. Nakamura, S.M. Russell, S.F. Ziegler, M. Tsang, X. Cao, W.J. Leonard, Interleukin-2 receptor γ chain: A functional component of the interleukin-7 receptor, Science 262 (1993) 1877-1880.
30. Y. Shi, R. Wang, A. Sharma, C. Gao, M. Collins, L. Penn, G.B. Mills, Dissociation of cytokine signals for proliferation and apoptosis, J. Immunol. 159 (1997) 5318-5328.
31. Y. Suminami, Y. Kashii, J.C. Law, W.C. Lin, J. Stanson, T.E. Reichert, H. Rabinowich, T.L. Whiteside, Molecular analysis of the IL-2 receptor β chain gene expressed in human tumor cells, Oncogene 16 (1998) 1309-1317.
32. L.F. Gulli, K.C. Palmer, Y.Q. Chen, K.B. Reddy, Epidermal growth factor-induced apoptosis in A431 cells can be reversed by reducing the tyrosine kinase activity, Cell Growth Differ. 7 (1996) 173-178.
33. M.P. Colombo, A. Modesti, G. Parmiani, G. Forni, Local cytokine availability elicits tumor rejection and systemic immunity through granulocyte-T-lymphocyte cross-talk, Cancer Res. 52 (1992) 4853-4857.
34. J. Bubenik, N.N. Voitenok, J. Kieler, V.S. Prassolov, P.M. Chumakov, D. Bubenikova, J. Simova, T. Jandlova, M. Indrova, Local administration of cells containing an inserted IL-2 gene and producing IL-2 inhibits growth of human tumours in nu/nu mice, Immunol. Lett. 19 (1988) 279-282.
35. G. Cortesina, A. De Stefani, M. Giovarelli, M.G. Barioglio, G.P. Cavallo, C. Jemma, G. Forni, Treatment of recurrent squamous cell carcinoma of the head and neck with low doses of interleukin-2 injected perilymphatically, Cancer 62 (1988) 2482-2485.