PET imaging in epilepsy: Basal ganglia and thalamic involvement

Epileptic Disorders

Volumn 4, Issue SUPPL. 3, 2002, Pages

  Semah, Franck ^a  

^a DIF   (France)

Author keywords

Basal ganglia; Dopamine; Epilepsy; Flumazenil; Fluorodeoxyglucose; Positron emission tomography; Seizure

Indexed keywords

FLUMAZENIL; FLUORODEOXYGLUCOSE F 18; LEVODOPA;

BASAL GANGLION; BRAIN BLOOD FLOW; BRAIN METABOLISM; CONFERENCE PAPER; DOPAMINERGIC SYSTEM; EPILEPSY; EPILEPTOGENESIS; FOCAL EPILEPSY; GABAERGIC SYSTEM; GENERALIZED EPILEPSY; HUMAN; NEUROMODULATION; NEUROTRANSMISSION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS;

BASAL GANGLIA; BRAIN CHEMISTRY; EPILEPSY; EPILEPSY, GENERALIZED; HUMANS; NEUROTRANSMITTER AGENTS; THALAMUS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036921131     PISSN: 12949361     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (29)

1. Deransart C, Vercueil L, Marescaux C, Depaulis A. The role of basal ganglia in the control of generalized absence seizures. Epilepsy Res 1998; 32: 213-23.
2. Rektor I, Kuba R, Brazdil M. Interictal and ictal EEG activity in the basal ganglia: an SEEG study in patients with temporal lobe epilepsy. Epilepsia 2002; 43: 253-62.
3. Newton MR, Berkovic SF, Austin MC, et al. Dystonia, clinical lateralization, and regional blood flow changes in temporal lobe seizures. Neurology 1992; 42: 371-7.
4. Henry TR, Mazziotta JC, Engel J Jr., et al. Quantifying interictal metabolic activity in human temporal lobe epilepsy. J Cereb Blood Flow Metab 1990; 10: 748-57.
5. Arnold S, Schlaug G, Niemann H, et al. Topography of interictal glucose hypometabolism in unilateral mesiotemporal epilepsy. Neurology 1996; 46: 1422-430.
6. DeCarli C, Hatta J, Fazilat S, et al. Extratemporal atrophy in patients with complex partial seizures of left temporal origin. Ann Neurol 1998; 43: 41-5.
7. Deasy NP, Jarosz JM, Elwes RC, Polkey CE, Cox TC. Thalamic changes with mesial temporal sclerosis: MRI. Neuroradiology 2000; 42: 346-51.
8. Dreifuss S, Vingerhoets FJ, Lazeyras F, et al. Volumetric measurements of subcortical nuclei in patients with temporal lobe epilepsy. Neurology 2001; 57: 1636-41.
9. 18F-FDG positron emission tomography (PET). Epilepsy Res 1997; 28: 233-43.
10. Swartz BE, Khonsari A, Brown C, et al. Improved sensitivity of 18FDG-positron emission tomography scans in frontal and "frontal plus" epilepsy. Epilepsia 1995; 36: 388-95.
11. Dupont S, Semah F, Samson Y, Baulac M. The underlying pathophysiology of ictal dystonia in temporal lobe epilepsy: an FDG-positron emission tomography study. Neurology 1998; 51: 1289-92.
12. Kotagal P, Lüders HO, Morris HH, et al. Dystonic posturing in complex partial seizures of temporal lobe onset: a new lateralizing sign. Neurology 1989; 39: 196-201.
13. Dupont S, Semah F, Boon PA, et al. Association of ipsilateral motor automatisms and contralateral dystonic posturing: a clinical feature differentiating medial temporal lobe epilepsy from neocortical temporal lobe epilepsy. Arch Neurol 1999; 56: 927-32.
14. Theodore WH, Brooks R, Margolin R, et al. Positron emission tomography in generalized seizures. Neurology 1985; 35: 684-90.
15. Swartz BE, Simpkins F, Halgren E, et al. Visual working memory in primary generalized epilepsy: an 18FDG-PET study. Neurology 1996; 47: 1203-12.
16. Mazière M, Hantraye P, Prenant C, Sastre J, Comar D. Synthesis of ethyl 8-fluoro-5.6-dihydro-5-(11C)methyl-6-oxo-4Himidazol(1.5-a) benzodiazepine-3-carboxylate (Ro 15-1788): a specific radioligand for in vivo study of central benzodiazepine receptors by positron emission tomography. Int J Appl Radiat Isotop 1984; 35: 973-8.
17. Burdette DE, Sakurai SY, Henry TR, et al. Temporal lobe central benzodiazepine binding in unilateral mesial temporal lobe epilepsy. Neurology 1995; 45: 934-41.
18. 11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy. Neurology 1997; 49: 764-73.
19. Ryvlin P, Bouvard S, Le Bars D, Mauguiere F. Transient and falsely lateralizing flumazenil-PET asymmetries in temporal lobe epilepsy. Neurology 1999; 53: 1882-5.
20. 18F]fluorodeoxyglucose-PET and MRI in refractory partial epilepsy. A prospective study of 100 patients. Brain 1998; 121: 2067-81.
21. 11C-flumazenil PET in patients with refractory temporal lobe epilepsy and normal MRI. Neurology 2000; 54: 332-9.
22. Bouilleret V, Dupont S, Spelle L, et al. Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography study. Ann Neurol 2002; 51: 202-8.
23. 11C]flumazenil and positron emission tomography. Epilepsia 1995; 36: 113-21.
24. Koepp MJ, Richardson MP, Brooks DJ, Cunningham VJ, Duncan JS. Central benzodiazepine/gamma-aminobutyric acid A receptors in idiopathic generalized epilepsy: an [11C]flumazenil positron emission tomography study. Epilepsia 1997; 38: 1089-97.
25. Savic I, Pauli S, Thorell JO, Blomqvist G. In vivo demonstration of altered benzodiazepine receptor density in patients with generalised epilepsy. J Neurol Neurosurg Psychiatry 1994; 57: 797-804.
26. Lamprecht F. Epilepsy and schizophrenia: a neurochemical bridge. J Neural Transm 1977; 40: 159-70.
27. Starr MS. The role of dopamine in epilepsy. Synapse 1996; 22: 159-94.
28. Ring HA, Trimble MR, Costa DC, et al. Striatal dopamine receptor binding in epileptic psychoses. Biol Psychiatry 1994; 35: 375-80.
29. Biraben A, Semah F, Ribeiro MJ, et al. Decreased striatal dopamine uptake in patients with epileptic seizures associated with ring chromosome 20 mosaicism. Epilepsia 2001; 42 (suppl 2): 175.