Effective anti-tumor adoptive immunotherapy: Utilization of exogenous IL-2-independent cytotoxic T lymphocyte clones

International Immunology

Volumn 14, Issue 12, 2002, Pages 1459-1468

  Iwashiro, Michihiro ^a   Jinyan, Wang ^b   Toda, Masaaki ^b   Linan, Wang ^b   Kato, Takuma ^b   Kuribayashi, Kagemasa ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adoptive transfer; IL 2 independent cytotoxic T lymphocytes clone; Memory cytotoxic T lymphocyte; Tumor eradication; VLA 4

Indexed keywords

BETA1 INTEGRIN; INTEGRIN; INTERLEUKIN 2;

ADOPTIVE IMMUNOTHERAPY; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; CELL SPECIFICITY; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE CLONE; MEMORY CELL; MIXED LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; REVIEW; SPLEEN; TUMOR CELL CULTURE;

ADOPTIVE TRANSFER; ANIMALS; CELL DIVISION; CLONE CELLS; IMMUNOTHERAPY, ADOPTIVE; INTEGRIN ALPHA4BETA1; INTERFERON TYPE II; INTERLEUKIN-2; MICE; MICE, INBRED C57BL; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; RNA, MESSENGER; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS;

EID: 0036919667     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxf107     Document Type: Review

References (42)

1. Coulie, P. G., Ikeda H., Baurain, J. F. and Chiari, R. 1999. Antitumor immunity at work in a melanoma patient. Adv. Cancer Res. 76:213.
2. Lindauer, M., Stanislawski, T., Haussler, A., Antunes, E., Cellary, A., Huber, C. and Theobald, M. 1998. The molecular basis of cancer immunotherapy by cytotoxic T lymphocytes. J. Mol. Med. 76:32.
3. Faure, F., Even, J. and Kourilsky P. 1998. Tumor-specific immune response: current in vitro analyses may not reflect the in vivo immune status. Crit. Rev. Immunol. 18:77.
4. Watanabe, Y., Kuribayashi, K., Miyatake, S., Nishihara, K., Nakayama, E. and Taniyama, T. 1989. Exogenous expression of mouse interferon-γ cDNA in mouse neuroblastoma C1300 cells resulted in reduced tumorigenicity by augmented anti-tumor immunity. Proc. Natl Acad. Sci. USA 86:9456.
5. Colombo, M. P. and Forni G. 1995. Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now? Immunol. Today 15:48.
6. Fong, L. and Engleman, E. G. 2000. Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 18:245.
7. Wang, R. F. and Rosenberg, S. A. 1999. Human tumor antigens for cancer vaccine development. Immunol. Rev. 170:85.
8. + T cells in adoptive immunotherapy and the indirect mechanism of tumor rejection. Crit. Rev. Immunol. 20:7.
9. Melief, C. J. and Kast, W. M. 1992. Lessons from T cell responses to virus induced tumours for cancer eradication in general. Cancer Surv. 13:81.
10. Rosenberg, S. A. and Terry, W. 1972. Passive immunotherapy of cancer in animals and man. Adv. Cancer Res. 25:323.
11. Keyaki, K., Kuribayashi, K., Sakaguchi, S., Masuda, T., Yamashita, J. Handa H. and Nakayama, E. 1985. Effector mechanisms of syngeneic anti-tumour responses in mice. II. Cytotoxic T lymphocytes mediate neutralization and rejection of radiation-induced leukaemia RL ♀ 1 in the nude mouse system. Immunology 56:141.
12. Cardoso, A. A., Veiga, J. P., Ghia, P., Afonso, H. M., Haining, W. N., Sallan S. E. and Nadler, L. M. 1999. Adoptive T-cell therapy for B-cell acute lymphoblastic leukemia: preclinical studies. Blood 94:3531.
13. Yee, C., Riddel, S. R. and Greenberg, P. D. 1997. Prospects for adoptive therapy. Curr. Opin. Immunol. 9:702.
14. Hammond-McKibben, D. M., Seth, A., Nagarkatti, P. S. and Nagarkatti, M. 1995. Characterization of factors regulating successful immunotherapy using a tumor-specific cytotoxic T lymphocyte clone: role of interleukin-2, cycling pattern of lytic activity and adhesion molecules. Int. J. Cancer 60:828.
15. LeFever, A. V., Truitt, R. L., Shih, C. C., Liepins, A. and Bortin, M. M. 1984. Migration patterns and functional activity of cloned cytotoxic T lymphocytes in syngeneic and allogeneic mice. Transplantation 37:410.
16. Byrne, J. A. and Oldstone, M. B. 1986. Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. VI. Migration and activity in vivo in acute and persistent infection. J. Immunol. 136:698.
17. Klarnet J. P., Matis, L. A., Kern, D. E., Mizuno, M. T., Peace, D. J., Thompson, J. A., Greenberg, P. D. and Cheever, M. A. 1987. Antigen-driven T cell clones can proliferate in vivo, eradicate disseminated leukemia, and provide specific immunologic memory. J. Immunol. 138:4012.
18. Hirama, T., Takeshita, S., Matsubayashi, Y., Iwashiro, M., Masuda, T., Kuribayashi, K., Yoshida, Y. and Yamagishi, H. 1991. Conserved V(D)J junctional sequence of cross-reactive cytotoxic T cell receptor idiotype and the effect of a single amino acid substitution. Eur. J. Immunol. 21:483.
19. Matsubayashi, Y., Hirama, T., Morioka, A., Iwashiro, M., Masuda, T., Uchino, H., Takeshita, S., Yamagishi, H,, Udono, H., Mieno, M., Nakayama, E., Shiku, H., Uenaka, A. and Kuribayashi, K. 1990. Participation of a dominant cytotoxic T cell population defined by a monoclonal antibody in syngeneic anti-tumor responses. Eur. J. Immunol. 20:2095.
20. Yagita, H., Nakamura, T., Karasuyama, H. and Okumura, K. 1989. Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc. Natl Acad. Sci. USA 86:645.
21. Nishimura, T., Yagi, H., Yagita, H., Uchiyama, Y. and Hashimoto, Y. 1985. Lymphokine-activated cell-associated antigen involved in broad-reactive killer cell-mediated cytotoxicity. Cell. Immunol. 94:122.
22. Miyake, K., Weissman, I. L., Greenberger, J. S. and Kincade, P. W. 1991. Evidence for a role of the integrin VLA-4 in lymphohemopoiesis. J. Exp. Med. 173:599.
23. 1 arrest. J. Immunol. Methods 236:37.
24. Hirsch, R., Chatenoud, L., Gress, R. E., Sachs, D. H., Bach, J. F. and Bluestone, J. A. 1989. Suppression of the humoral response to anti-CD3 monoclonal antibody. Transplantation 47:853.
25. Kondo, T., Uenishi, H., Shimizu, T., Hirama, T., Iwashiro, M., Kuribayashi, K., Tamamura, H., Fujii, N., Fujisawa, R., Miyazawa, M. and Yamagishi, H. 1995. A single retroviral gag precursor signal peptide recognized by FBL-3 tumor-specific cytotoxic T lymphocytes. J. Virol. 69:6735.
26. Chen, W., Qin H, Chesebro, B. and Cheever, M. A. 1996. Identification of a gag-encoded cytotoxic T-lymphocyte epitope from FBL-3 leukemia shared by Friend, Moloney, and Rauscher murine leukemia virus-induced tumors. J. Virol. 70:7773.
27. Uenishi, H., Iwanami, N., Kuribayashi, K., Tamamura, H., Fujii, N., Nakatani, T., Kawasaki, T. and Yamagishi, H. 1998. Overlapping epitopes of Friend murine leukemia virus gag-encoded leader sequence recognized by single cytotoxic T-lymphocyte clones. Immunol. Lett. 62:33.
28. Tsai, V., Kawashima, I., Keogh, E., Daly, K., Sette, A. and Celis, E. 1998. In vitro immunization and expansion of antigen-specific cytotoxic T lymphocytes for adoptive immunotherapy using peptide-pulsed dendritic cells. Crit. Rev. Immunol. 18:65.
29. Sun, Y., Moller, P., Berking, C., Schlupen, E. M,, Volkenandt, M. and Schadendorf, D. 1999. In vivo selective expansion of a tumour-specific cytotoxic T-cell clone derived from peripheral blood of a melanoma patient after vaccination with gene-modified autologous tumour cells. Immunology 98:535.
30. + cytolytic clones which recognize a tumor-specific cell surface antigen. J. Immunol. 135:703.
31. + T cells are hyperreactive to antigenic challenge in vitro. J. Exp. Med. 184:2141.
32. Cho, B. K., Wang, C., Sugawa, S., Eisen, H. N. and Chen, J. 1999. Functional differences between memory and naïve CD8 T cells. Proc. Natl Acad. Sci. USA 96:2976.
33. Saparov, A., Wagner, F. H., Zheng, R., Oliver, J. R., Maeda, H., Hockett, R. D. and Weaver, C. T. 1999. Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/ effector function. Immunity 11:271.
34. + T cell clones correlates with their levels of expression of adhesion molecules. J. Exp. Med. 175:895
35. Hauzenberger, D., Klominek, J., Bergstrom, S. E. and Sundqvist, K. G. 1995. T lymphocyte migration: the influence of interactions via adhesion molecules, the T cell receptor, and cytokines. Crit. Rev. Immunol. 15:5.
36. Duke, R. C. and Cohen, J. J. 1986. IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res. 5:289.
37. Dailey, M. O., Fathman, C. G., Butcher, E. C., Pillemer, E. and Weissman, I. 1982. Abnormal migration of T lymphocyte clones. J. Immunol. 128:2134.
38. Dailey, M. O., Gallatin, W. M., Kraal, G., Butcher, E. and Weissman, I. 1985. T cell clones: a model of a non-recirculating phase of T cell differentiation. Adv. Exp. Med. Biol. 186:621.
39. Opferman, J. T., Ober, B. T. and Ashton-Rickardt, P. G. 1999. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 283:1745.
40. Di Somma, M. M., Somma, F., Montani, M. S., Mangiacasale, R., Cundari, E. and Piccolella, E. 1999. TCR engagement regulates differential responsiveness of human memory T cells to Fas (CD95)-mediated apoptosis. J. Immunol. 162:3851.
41. Tough, D. F., Sun, S., Zhang, X. and Sprent, J. 1999. Stimulation of naive and memory T cells by cytokines. Immunol. Rev. 170:39.
42. + memory T cells by opposing cytokines. Science 288:675.