Independence of the product of solubility and distribution coefficient of pH

Pharmaceutical Research

Volumn 19, Issue 12, 2002, Pages 1862-1866

  Ni, Nina ^a   Sanghvi, Tapan ^a   Yalkowsky, Samuel H ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Absorption potential; Octanol buffer distribution coefficient; Octanol water partition coefficient; pH; Solubility

Indexed keywords

ACETYLSALICYLIC ACID; AMINOPHENAZONE; BUFFER; CHLORDIAZEPOXIDE; CHLORPROMAZINE; DIAZEPAM; DICLOFENAC; IBUPROFEN; INDOMETACIN; KETOPROFEN; LIDOCAINE; MEDAZEPAM; MEFENAMIC ACID; MELOXICAM; METHYLPHENOBARBITAL; NAPROXEN; OCTANOL; OXOLINIC ACID; OXYPHENBUTAZONE; PELRINONE; PHENOBARBITAL; PHENYLBUTAZONE; PHENYTOIN; PINDOLOL; QUINOLINOL DERIVATIVE; SALICYLIC ACID; WATER;

ARTICLE; CALCULATION; DRUG ABSORPTION; GASTROINTESTINAL ABSORPTION; PARTITION COEFFICIENT; PH; PKA; PRIORITY JOURNAL; SOLUBILITY; SOLUTE;

HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; SOLUBILITY;

EID: 0036918103     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021449709716     Document Type: Article

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