Prediction of distribution coefficients from structure. Comparison of calculated and experimental data for various drugs

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 24, Issue 3, 1999, Pages 205-212

  Tsantili Kakoulidou, A ^a   Panderi, I ^a   Piperaki, S ^a   Csizmadia, F ^b   Darvas, F ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b CompuDrug Chemistry Ltd ^*  (Hungary)

Author keywords

Distribution coefficient; Ionization; Lipophilicity; Prediction method

Indexed keywords

ACEBUTOLOL; ALPRENOLOL; AMIFLOXACIN; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUFFER; BUNITROLOL; CIPROFLOXACIN; CLONIDINE DERIVATIVE; DIAZEPAM; ION; LABETALOL; LOMEFLOXACIN; METOPROLOL; NADOLOL; NORFLOXACIN; OFLOXACIN; OXPRENOLOL; PEFLOXACIN; PINDOLOL; PROMETHAZINE; PROPRANOLOL; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SOTALOL; SULFAMETHOXAZOLE; TIMOLOL; TOLAMOLOL;

ARTICLE; CALCULATION; COMPARATIVE STUDY; COMPUTER PROGRAM; CONSTANTS AND COEFFICIENTS; DRUG CONCENTRATION; DRUG DISTRIBUTION; DRUG RESEARCH; DRUG STRUCTURE; IONIC STRENGTH; MATHEMATICAL ANALYSIS; PH; PREDICTION;

EID: 0033384221     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190022     Document Type: Article

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