Peripheral and central sex steroids have differential effects on the HPA axis of male and female rats

Stress

Volumn 5, Issue 4, 2002, Pages 235-247

  McCormick, Cheryl M ^a   Linkroum, William ^a   Sallinen, Bethany J ^a   Miller, Nicholas W ^a  

^a BATES COLLEGE   (United States)

Author keywords

ACTH; Androgen; CBG; Corticosterone; Estrogen; Medial preoptic area

Indexed keywords

ANDROGEN; ANDROSTANOLONE; CORTICOSTERONE; CORTICOTROPIN; ESTRADIOL BENZOATE; ESTROGEN; TESTOSTERONE PROPIONATE; TRANSCORTIN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; FEMALE; GENDER; HORMONAL REGULATION; HORMONAL THERAPY; HORMONE ACTION; HORMONE RELEASE; HORMONE SUBSTITUTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMPLANT; MALE; MEDIAL PREOPTIC AREA; MEDICAL LITERATURE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SILICONE PROSTHESIS; STRESS;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; CATHETERIZATION; CORTICOSTERONE; DIHYDROTESTOSTERONE; DRUG IMPLANTS; ESTRADIOL; FEMALE; GONADAL STEROID HORMONES; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; PITUITARY-ADRENAL SYSTEM; PREOPTIC AREA; RATS; RATS, LONG-EVANS; SEX CHARACTERISTICS; SKIN; TESTOSTERONE; TRANSCORTIN;

EID: 0036913533     PISSN: 10253890     EISSN: None     Source Type: Journal    
DOI: 10.1080/1025389021000061165     Document Type: Article

References (111)

1. Akesson, T., Simerly, R. and Micevych, P. (1988) "Estrogen concentrating hypothalamic and limbic neurons project to the medial preoptic nucleus", Brain Res. 451, 381-385.
2. Allen-Rowlands, C.F., Allen, J.P., Greer, M.A. and Wilson, M. (1980) "Circadian rhythmicity of ACTH and corticosterone in the rat", J. Endocrinol. Investig. 4, 371-377.
3. Almeida, O.F.X., Hassan, A.H.S., Harbuz, M.S., Linton, E.A. and Lightman, S.L. (1992) "Hypothalamic corticotropin-releasing hormone and opioid peptide neurons: Functional changes after adrenalectomy and/or castration", Brain Res. 571, 189-198.
4. Begue, R.J., Gustafsson, J.A. and Gustafsson, S.A. (1973) "Irreversible neonatal differentiation of corticosterone metabolism in rats in vivo", Eur. J. Biochem. 40, 361-366.
5. Bingaman, E.W., Magnuson, D.J., Gray, T.S. and Handa, R.J. (1994) "Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy", Neuroendocrinology 59, 228-234.
6. Bloch, G.J., Kurth, S.M., Akesson, T.R. and Micevych, P.E. (1992) "Estrogen-concentrating cells within cell groups of the medial preoptic area: Sex differences and co localization with galanin-immunoreactive cells", Brain Res. 595, 301-308.
7. Bohler, H.C.L., Zoeller, R.T., King, J.C., Rubin, B.S., Weber, R. and Merriam, G.R. (1990) "Corticotropin releasing hormone mRNA is elevated on the afternoon of proestrus in parvocellular paraventricular nuclei of the female rat", Mol. Brain Res. 8, 259-262.
8. Bradbury, M., Cascio, C., Scribner, K. and Dallman, M. (1991) "Stress-induced adrenocorticotropin secretion: Diurnal responses and decreases during stress in the evening are not dependent on corticosterone", Endocrinology 128, 680-688.
9. Bradford, M. (1976) "A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding", Anal. Biochem. 72, 248-252.
10. Brown, L.L., Siegel, H. and Etgen, A.M. (1996) "Global sex differences in stress-induced activation of cerebral metabolism revealed by 2-deoxyglucose autoradiography", Horm. Behav. 30, 611-617.
11. Buckingham, J., Dohler, K. and Wilson, C. (1978) "Activity of the pituitary-adrenocortical secretion and thyroid gland during the oestrous cycle of the rat", J. Endocrinol. 78, 359-366.
12. Buijs, R.M., Wortel, J., Van Heerikhuize, J.J. and Kalsbeek, A. (1997) "Novel environment induced inhibition of corticosterone secretion: Physiological evidence for a suprachiasmatic nucleus mediated neuronal hypothalamo-adrenal cortex pathway", Brain Res. 758, 229-236.
13. Burgess, L.H. and Handa, R.J. (1992) "Chronic estrogen-induced alterations in adrenocorticotropin and corticosterone secretion, and glucocorticoid receptor-mediated functions in female rats", Endocrinology 131, 1261-1269.
14. Carey, M.P., Detard, C.H., de Koning, J., Helmerhorst, F. and de Kloet, E.R. (1995) "The influence of ovarian steroids on hypothalamic-pituitary-adrenal regulation in the female rat", J. Endocrinol. 144, 311-321.
15. Carter, D.A., Saridaki, E. and Lightman, S.L. (1988) "Sexual differentiation of oxytocin stress responsiveness: Effect of neonatal androgenization, castration and a luteinizing hormone-releasing hormone antagonist", Acta Endocrinol. 117, 525-530.
16. Chen, X. and Herbert, J. (1995) "The effect of long-term castration on neuronal and physiological responses to acute or repeated restraint stress: Interactions with opioids and prostaglandins", J. Neuroendocrinol. 7, 137-144.
17. Cheung, C.Y. and Davidson, J.M. (1977) "Effects of testosterone implants and hypothalamic lesions on luteinizing hormone regulation in the castrated male rat", Endocrinology 100, 292-302.
18. Colby, H.D. and Kitay, J.I. (1972a) "Effects of gonadal hormones on adrenal steroid metabolism in vitro", Steroids 20, 143-157.
19. Colby, H.D. and Kitay, J.I. (1972b) "Effects of gonadal hormones on adrenocortical secretion of 5 alpha-reduced metabolites of corticosterone in the rat", Endocrinology 91, 1523-1527.
20. Conrad, L. and Pfaff, D. (1975) "Axonal projections of medial preoptic and anterior hypothalamic neurons", Science 190, 1112-1114.
21. Critchlow, V., Liebelt, R.A., Bar-Sela, M., Mountcastle, W. and Lipscomb, H.S. (1963) "Sex difference in resting pituitary-adrenal function in the rat", Am. J. Physiol., 807-815.
22. Dagnault, A. and Richard, D. (1997) "Involvement of the medial preoptic area in the anorectic action of estrogens", Am. J. Physiol. 272, R311-R317.
23. Dallman, M., Akana, S., Cascio, C., Darlington, D., Jacobson, L. and Levin, N. (1987) "Regulation of ACTH secretion: Svariations on a theme of B", Rec. Progr. Horm. Res. 43, 113-173.
24. Denef, C. and De Moor, P. (1972) "Sexual differentiation of steroid metabolizing enzymes in the rat liver. Further studies on predetermination by testosterone at birth", Endocrinology 91, 374-384.
25. Feldman, D., Mondon, C.E., Homer, J.A. and Weiser, J.N. (1979) "Glucocorticoid and estrogen regulation of corticosteroid-binding globulin production by rat liver", Am. J. Physiol. 237, E493-E499.
26. Gentry, R.T and Wade, G.N. (1976) "Androgenic control of food intake and body weight in male rats", J. Comp. Physiol. Psychol. 90, 18-25.
27. Gorski, R., Gordon, J., Shryne, J. and Southam, A. (1978) "Evidence for a morphological sex difference within the medial preoptic area of the rat brain", Brain Res. 148, 333-346.
28. Grattan, D., Rocca, M., Sagrillo, C., McCarthy, M. and Selmanoff, M. (1996) "Antiandrogen microimplants into the rostral medial preoptic area decrease gamma-aminobutyric acidergic neuronal activity and increase luteinizing hormone secretion in the intact male rat", Endocrinology 137, 4167-4173.
29. Handa, R.J., Nunley, K.M., Lorens, S.A., Louie, J.P., McGivem, R.E R.F. and Bollnow, M.R. (1994) "Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors" Physiol. Behav. 55, 117-124.
30. Handa, R.J., Kerr, J.E., DonCarlos, L.L., McGivem, R.F. and Jejna, G. (1996) "Hormonal regulation of androgen receptor messenger RNA in the medial preoptic area of the male rat", Mol. Brain Res. 39, 57-67.
31. Hasegawa, T. and Sakuma, Y. (1993) "Developmental effect of testosterone on estrogen sensitivity of the rat preoptic neurons with axons to the ventral tegmental area", Brain Res. 611, 1-6.
32. Herman, J.P., Prewitt, C.M.F. and Cullinan, W.E. (1996) "Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis", Crit. Rev. Neurobiol. 10, 371-394.
33. Horvath, T. (1998) "An alternate pathway for visual signal integration into the hypothalamo-pituitary axis: Retinorecipient intergeniculate neurons project to various regions of the hypothalamus and innervate neuroendocrine cells including those producing dopamine", J. Neurosci. 18, 1546-1558.
34. Jansson, J.O., Oscarsson, J., Mode, A. and Ritzen, E.M. (1989) "Plasma growth hormone pattern and androgens influence the levels of corticosteroid-binding globulin in rat serum", J. Endocrinol. 122, 725-732.
35. Kalimi, M. and Hubbard, J.R. (1983) "Development of an exchange assay for cytosolic glucocorticoid receptors using the synergistic effects of molybdate plus dithiothreitol", Endocrinology 113, 1161-1163.
36. Kaneko, M., Kaneko, K., Shinsako, J. and Dallman, M.F. (1981) "Adrenal sensitivity to adrenocorticotrophin varies diurnally", Endocrinology 109, 70-75.
37. Kant, G.J., Lenox, R.H., Bunnell, B.N., Mougey, E.H., Pennington, L.L. and Meyerhoff, J.L. (1983) "Comparison of stress response in male and female rats: Pituitary cyclic AMP and plasma prolactin growth hormone and corticosterone", Psychoneuroendocrinology 8, 421-428.
38. Karandrea, D., Kittas, C. and Kitraki, E. (2000) "Contribution of sex and cellular context in the regulation of brain corticosteroid receptors following restraint stress", Neuroendocrinology 71, 343-353.
39. Kerr, J.E., Beck, S.G. and Handa, R.J. (1996) "Androgens modulate glucocorticoid receptor mRNA, but not mineralocorticoid receptor mRNA levels, in the rat hippocampus", J. Neuroendocrinol. 8, 439-447.
40. Kitay, J.I. (1961) "Sex differences in adrenal cortical secretion in the rat", Endocrinology 68, 818-824.
41. Kitay, J.I. (1963) "Pituitary-adrenal function in the rat after gonadectomy and gonadal hormone replacement", Endocrinology 73, 253-260.
42. Kitay, J.I., Coyne, M.D. and Swygert, N.H. (1970) "Influence of gonadectomy and replacement with estradiol or testosterone on formation of 5 alpha-reduced metabolites of corticosterone by the adrenal gland of the rat", Endocrinology 87, 1257-1265.
43. Lesniewska, B., Miskowiak, B., Nowak, M. and Malendowicz, L.K. (1990a) "Sex differences in adrenocortical structure and function. XXVII. The effect of ether stress on ACTH and corticosterone in intact gonadectomized and testosterone- or estradiol-replaced rats", Res. Exp. Med. 190, 95-103.
44. Lesniewska, B., Nowak, M. and Malendowicz, L.K. (1990b) "Sex differences in adrenocortical structure and function", Horm. Metab. Res. 22, 378-381.
45. Libertun, C. and Lau, C. (1972) "Adrenocortical function in prepuberal rats: Neonatal effects of testosterone", J. Endocrinol. 55, 221-222.
46. Liebmann, J. and Matsumoto, A. (1990) "Acute selective withdrawal of testosterone negative feedback increases luteinizing hormone secretion without altering hypothalamic catecholaminergic neuronal activity", Endocrinology 126, 555-564.
47. Lisciotto, C. and Morrell, J.I. (1994) "Sex differences in the distribution and projections of testosterone target neurons in the medial preoptic area and the bed nucleus of the stria terminalis of rats", Horm. Behav. 28, 492-502.
48. Lobo, R.A., March, C.M., Goebelsmann, U., Krauss, R.M. and Mishell, Jr, D.R. (1980) "Subdermal estradiol pellets following hysterectomy and oophorectomy. Effect upon serum estrone estradiol, luteinizing hormone, follicle-stimulating hormone, corticosteroid binding globulin-binding capacity, testosterone-estradiol binding globulin-binding capacity, lipids, and hot flushes", Am. J. Obstet. Gynecol. 138, 714-719.
49. Low S.C., Assaad, S.N., Rajan, V., Chapman, K.E. Edwards, C.R. and Seckl J.R. (1993) "Regulation of 11 beta-hydroxysteroid dehydrogenase by sex steroids in vivo: Further evidence for the existence of a second dehydrogenase in rat kidney", J. Endocrinol. 139, 27-35.
50. Malendowicz, L.K. and Mlynarczyk, W. (1982) "Sex differences in adrenocortical structure and function. X. Lipid and corticosterone in the rat adrenal as affected by gonadectomy and testosterone or estradiol replacement", Endokrinologie 79, 292-300.
51. Martignoni, E., Costa A., Sinforiani, E., Liuzzi, A., Chiodini, P., Mauri M., Bono, G. and Nappi, G. (1992) "The brain as a target for adrenocortical steroids: Cognitive implications", Psychoneuroendocrinology 17, 343-354.
52. Martin, C.E., Cake, M.H., Hartmann, P.E. and Cook. I.F. (1977) "Relationship between foetal corticosteroids, maternal progesterone, and parturition in the rat", Acta Endocrinol. 84, 167-176.
53. Mataradze, G.D., Kurabekova, R.M. and Rozen, V.B. (1992) "The role of sex steroids in the formation of sex-differentiated concentrations of corticosteroid-binding globulin in rats", J. Endocrinol. 132, 235-240.
54. McAbee, M.D. and DonCarlos, L.L. (1998) "Ontogeny of region-specific sex differences in androgen receptor messenger ribonucleic acid expression in the rat forebrain", Endocrinology 139, 1738-1745.
55. McCormick, C.M. and Mahoney, E.M. (1999) "Persistent effects of prenatal, neonatal, or adult treatment with flutarmide on the hypothalamic-pituitary-adrenal stress response of adult rats", Horm. Behav. 35, 90-101.
56. McCormick, C.M. and Miller, N.W. (2000) "Androgen-mediated effects of lesions of the anterior (lateral) BNST on stress-induced corticosterone release", Soc. Neurosci. Abstr. 30, 80.
57. McCormick, C.M., Smythe, J.W., Sharma, S. and Meaney, M.J. (1995) "Sex-specific effects of prenatal stress on hypothalamic-pituitary-adrenal responses to stress and brain glucocorticoid receptor density in adult rats", Dev. Brain Res. 84, 55-61.
58. McCormick, C.M., Furey, B.F., Child, M., Sawyer M.J., and Donohue, S.M. (1998a) "Neonatal sex hormones have organizational effects on the hypothalamic-pituitary-adrenal axis of male rats" Dev. Brain Res. 105, 295-307.
59. McCormick, C.M., Kehoe, P. and Kovacs, S. (1998b) "Corticosterone release in response to repeated, short episodes of neonatal isolation: Evidence of sensitization", Int. J. Dev. Neurosci. 16, 175-185.
60. McDonald, A. (1988) "Projections of the intermediate subdivision of the central amygdaloid nucleus to the bed nucleus of the stria terminalis and medial diencephalon", Neurosci. Lett. 85, 285-290.
61. Meaney, M.J., Aitken, D.H., Sharma, S. and Viau, V. (1992) "Basal ACTH corticosterone, and corticosterone-binding globulin levels over the diurnal cycle, and hippocampal type I and type II corticosteroid receptors in young and old, handled and nonhandled rats", Neuroendocrinology 55, 204-213.
62. Nett, S., Jorge-Rivera, J., Myers, M., Clark, A. and Henderson, L. (1999) "Properties and sex-specific differences of GABAA receptors in neurons expressing gammal subunit mRNA in the preoptic area of the rat", J. Neurophysiol. 81, 192-203.
63. Nock, B., Cicero, T.J. and Wich, M. (1998) "Chronic exposure to morphine decreases physiologically active corticosterone in both male and female rats but by different mechanisms ", J. Pharmacol. Exp. Ther. 286, 875-882.
64. Nock, B., Wich, M., Cicero, T.J. and O'Connor, L.H. (2000) "Testosterone is required for corticosteroid-binding globulin upregulation by morphine to be fully manifested", Pharmacol., Biochem. Behav. 67, 193-198.
65. Nowak, K.W., Neri, G., Nussdorfer, G.G. and Malendowicz, L.K. (1995) "Effects of sex hormones on the steroidogenic activity of dispersed adrenocortical cells of the rat adrenal cortex", Life Sci. 57, 833-837.
66. O'Brien, J.T., Ames, D., Schweitzer, I., Colman, P., Desmond, P. and Tress, B. (1996) "Clinical and magnetic resonance imaging correlates of hypothalamic-pituitary-adrenal axis function in depression and Alzheimer's disease", Br. J. Psychiatry 168, 679-687.
67. Ogilvie, K.M. and Rivier, C. (1997) "Gender difference in hypothalamic-pituitary-adrenal axis response to alcohol in the rat: Role of gonadal steroids", Brain Res. 766, 19-28.
68. Orr, T.E., Meyerhoff, J.L., Mougey, E.H. and Bunnell, B.N. (1990) "Hyperresponsiveness of the rat neuroendocrine system due to repeated exposure to stress", Psychoneuroendocrinology 15, 317-328.
69. Ottenweller, J.E., Servatius, R.J. and Natelson, B.H. (1994) "Repeated stress persistently elevates morning, but not evening, plasma corticosterone levels in male rats", Physiol. Behav. 55, 337-340.
70. Patchev, V.K. and Almeida, O.F.X. (1998) "Gender specificity in the neural regulation of the response to stress", Mol. Neurobiol. 16, 63-77.
71. Patchev, V.K., Hayashi, S., Orikasa, C. and Almeida, O.F.X. (1995) "Implications of estrogen-dependent brain organization for gender differences in hypothalamo-pituitary-adrenal regulation", FASEB 9, 419-423.
72. Paulmyer-Lacroix, O., Hery, M., Pugeat, M. and Grino, M. (1996) "The modulatory role of estrogens on corticotropin-releasing factor gene expression in the hypothalamic paraventricular nucleus of ovariectomized rats: Role of the adrenal gland", J. Neuroendocrinol. 8, 515-519.
73. Paxinos, G. and Watson, C. (1982) The Rat Brain in Stereotaxic Coordinates (Academic Press, Sydney).
74. Peiffer, A. and Barden, N. (1987) "Estrogen-induced decrease of glucocorticoid receptor messenger ribonucleuic acid concentration in rat anterior pituitary gland", Mol. Endocrinol. 1, 435-440.
75. Pellegrini, A., Grieco, M., Materazzi, G., Gesi, M. and Ricciardi, M.P. (1998) "Stress-induced morphohistochemical and functional changes in rat adrenal cortex, testis and major salivary glands", Histochem. J. 30, 68-701.
76. Pericic, D., Bujas, M., Mirkovic, K. and Jazvinscak, M. (1999) "Effects of adrenalectomy and gonadectomy on sex and stress-induced differences in bicuculline-induced convulsions", Exp. Brain Res. 129, 451-456.
77. Petersen, S., McCrone, S., Keller, M. and Shores, S. (1995) "Effects of estrogen and progesterone on luteinizing hormone-releasing hormone messenger ribonucleic acid levels: Consideration of temporal and neuroanatomical variables", Endocrinology 136, 3604-3610.
78. Pike, C.J. (1999) "Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: Relevance to Alzheimer's disease", J. Neurochem. 72, 1552-1563.
79. Prezant, D.J., Valentine, D.E., Gentry, E.I., Richner, B., Cahill, J. and Freeman, K. (1993) "Effects of short-term and long-term androgen treatment on the diaphragm in male and female rats", J. Appl. Physiol. 75, 1140-1149.
80. Pugeat, M., Lejeune, H., Mazenod, B., Dechaud, H., Fleury, M.C. and Tourniaire, J. (1988) "Changes in plasma binding protein of sex steroids and transcortin during the treatment of menopause with oral estrogens", Presse Medicale 17, 1189-1192.
81. Roselli, C.E. and Resko, J.A. (1997) "Sex differences in androgen-regulated expression of cytochrome P450 aromatase in the rat brain", J. Steroid Biochem. Mol. Biol. 61, 365-374.
82. Roselli, C.E. and Klosterman, S.A. (1998) "Sexual differentiation of aromatase activity in the rat brain: Effects of perinatal steroid exposure", Endocrinology 139, 3193-3201.
83. Roselli, C., Horton, L. and Resko, J. (1985) "Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system", Endocrinology 117, 2471-2477.
84. Roselli, C.E., Horton, L.E. and Resko, J.A. (1987) "Time-course and steroid specificity of aromatase induction in rat hypothalamus-preoptic area", Biol. Reprod. 37, 628-633.
85. Roselli, C.E., Handa, R.J. and Resko, J.A. (1989) "Quantitative distribution of nuclear androgen receptors in microdissected areas of the rat brain", Neuroendocrinology 49, 449-453.
86. Sage, D., Maurel, D. and Bosler, O 0. (2001) "Involvement of the suprachiasmatic nucleus in diurnal ACTH and corticosterone responsiveness to stress", Am. J. Physiol. Endocrinol. Metab. 280, E260-E269.
87. Sar, M. and Stumpf, W. (1977) "Distribution of androgen target cells in rat forebrain and pituitary after [3H]-dihydrotestosterone administration", J. Steroid Biochem. 8, 1131-1135.
88. Sibilia, V., Cocchi, D., Pagani, E, Pecile, A. and Netti, C. (2000) "The influence of sex and gonadectomy on the growth hormone and corticosterone response to hexarelin in the rat", Life Sci. 68, 321-329.
89. Sillence, M.N. and Rodway, R.G. (1990) "Effects of trenbolone acetate and testosterone on growth and on plasma concentrations of corticosterone and ACTH in rats", J. Endocrinol. 126, 461-466.
90. Simerly, R. and Swanson, L. (1988) "Projections of the medial preoptic nucleus: A Phaseolus vulgaris leucoagglutinin anterograde tractt-racing study in the rat", J. Comp. Neurol. 270, 209-242.
91. Simerly, R., Chang, C., Muramatsu, M. and Swanson, L. (1990) "Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study", J. Comp. Neurol. 294, 76-95.
92. Simpkins, J.W., Green, P.S., Gridley, K.E., Singh, M., deFiebre, N.C. and Rajakumar, G. (1997) "Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease", Am. J. Med. 103, 19s-25s.
93. Smith, C.J. and Norman, R.L. (1987a) "Circadian periodicity in circulating cortisol is absent after orchidectomy in rhesus macaques", Endocrinology 121, 2186-2191.
94. Smith, C.J. and Norman, R.L. (1987b) "Influence of the gonads on cortisol secretion in female rhesus macaques", Endocrinology 121, 2192-2198.
95. Swanson, L. (1976) "An autoradiographic study of the efferent connections of the preoptic region in the rat", J. Comp. Neurol. 167, 227-256.
96. Tannenbaum, B., Rowe, W., Sharma, S., Diorio, J., Steverman, A., Walker, M. and Meaney, M.J. (1997) "Dynamic variations in plasma corticosteroid-binding globulin and basal HPA activity following acute stress in adult rats", J. Neuroendocrinol. 9, 163-168.
97. Telegdy, G., Schreiberg, G. and Endroczi, E. (1964) "Effect of oestrogens implanted into the hypothalamus on the activity of the pituitary-adrenocortical system", Acta Physiol. Hung. 25, 229-234.
98. Viau, V., Chu, A., Soriano, L. and Dallman, M. (1999) "Independent and overlapping effects of corticosterone and testosterone on corticotropin-releasing hormone and arginine vasopressin mRNA expression in the paraventricular nucleus of the hypothalamus and stress-induced adrenocorticotropic hormone release", J. Neurosci. 19, 6684-6693.
99. Viau, V. and Meaney, M.J. (1991) "Variations in the hypothalamic-pituitary-adrenal response to stress during the estrous cycle in the rat", Endocrinology 129, 2503-2511.
100. Viau, V. and Meaney, M.J. (1996) "The inhibitory effect of testosterone on hypothalamic-pituitary-adrenal responses to stress is mediated by the medial preoptic area", J. Neurosci. 16, 1866-1876.
101. Viau, V., Soriano, L. and Dallman, M.F. (2001) "Androgens alter corticotropin releasing hormone and arginine vasopressin mRNA within forebrain sites known to regulate activity in the hypothalamic-pituitary-adrenal axis", J. Neuroendocrinol. 13, 442-452.
102. Wade, G.N. (1975) "Some effects of ovarian hormones on food intake and body weight in female rats", J. Comp. Physiol. Psychol. 88, 183-193.
103. Walker, C.-D., Akana, S.F., Cascio, C.S. and Dallman, M.F. (1990) "Adrenalectomy in the neonate: Adult-like adrenocortical system responses to both removal and replacement of corticosterone", Endocrinology 127, 832-842.
104. Walker, Q.D., Francis, R., Cabassa, J. and Kuhn, C.M. (2001) "Effect of ovarian hormones and estrous cycle on stimulation of the hypothalamo-pituitary-adrenal axis by cocaine", J. Pharmacol. Exp. Ther. 297, 291-298.
105. Watts, A.G. and Swanson, L.W. (1989) "Diurnal variations in the content of preprocorticotropin-releasing hormone messenger ribonucleic acids in the hypothalamic paraventricular nucleus of rats of both sexes as measured by in situ hybridization", Endocrinology 125, 1734-1738.
106. de Weerdt, O. and Gooren, L.J. (1992) "Patterns of serum cortisol concentrations in ovariectomized females with and without androgen administration", Horm. Metabol. Res. 24, 82-84.
107. Wilson, M.A. and Biscardi, R. (1994) "Sex differences in GABA/benzodiazepine receptor changes and corticosterone release after acute stress in rats", Exp. Brain Res. 10, 297-306.
108. Witkin, J., Paden, C. and Silverman, A. (1982) "The luteinizing hormone-releasing hormone (LHRH) systems in the rat brain", Neuroendocrinology 35, 429-438.
109. Yokosuka, M., Okamura, H. and Hayashi, S. (1997) "Postnatal development and sex difference in neurons containing estrogen receptor-alpha immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat", J. Comp. Neurol. 389, 81-93.
110. Young, E.A. (1996) "Sex differences in response to exogenous corticosterone: A rat model of hypercortisolemia", Mol. Psychiatry 1, 313-319.
111. Zhou, L., Blaustein, J. and De Vries, G. (1994) "Distribution of androgen receptor immunoreactivity in vasopressin- and oxytocin-immuno-reactive neurons in the male rat brain", Endocrinology 134, 2622-2627.