Cystic fibrosis transport regulator and its mRNA are expressed in human epidermis

Journal of Investigative Dermatology

Volumn 119, Issue 6, 2002, Pages 1224-1230

  Sato, Fusako ^a,b   Soos, Gyula ^a,b   Link Jr , Charles ^a,b   Sato, Kenzo ^a,b,c  

^a Iowa Health System   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c Dubuque Dermatology Clinic   (United States)

Author keywords

Cystic fibrosis; Cystic fibrosis transport regulator; Epidermis; Immunohistochemistry; In situ hybridization; Sweat gland

Indexed keywords

COMPLEMENTARY RNA; CYSTIC FIBROSIS TRANSPORT REGULATOR; EPITOPE; MESSENGER RNA; MONOCLONAL ANTIBODY; PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL CELL; BASE PAIRING; CARBOXY TERMINAL SEQUENCE; CELL TYPE; CONTROLLED STUDY; CYTOPLASM; EPIDERMIS; EXON; FEMALE; GRANULAR CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MYOEPITHELIUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROBE; RNA SEQUENCE; STRATUM CORNEUM; SWEAT GLAND;

EID: 0036911395     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2002.19601.x     Document Type: Article

References (31)

1. Cohn JA, Melhus O, Page LJ, Dittrich KL, Vigna SR: CFTR development of high-affinity antibodies and localization in sweat gland. Biochem Biophys Res Comm 181:36-43, 1991
2. Collins FS: Cystic fibrosis. Molecular and therapeutic implications. Science 256: 774-779, 1992
3. Crawford I, Maloney PC, Zeitlin PL, et al: Immunocytochemical localization of the cystic fibrosis gene product CFTR. Proc Natl Acad Sci 88:9262-9266, 1991
4. Davies JC, Stern M, Dewar A, et al: CRTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium. Am J Respir Cell Mol Biol 16:657-663, 1997
5. Denning GM, Ostedgaard LS, Cheng SH, Smith AE, Welsh MJ: Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia. J Clin Invest 89:339-349, 1992
6. Devuyst D, Goldstein PE, Sanches MV, et al: Expression of CFTR in human and bovine thyroid epithelium. Am J Physiol 272(Cell Physiol 41): 1299-C1308, 1997
7. Drumm ML, Wilkinson DJ, Smit LS, et al: Chloride conductance expressed by ΔF508 and other mutant CFTRs in Xenopus oocytes. Science 254:1797-1799, 1991
8. Engelhardt JF, Yankaskas JR, Ernst SA, et al: Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet 2:240-248, 1992
9. Gregory RJ, Cheng SH, Rick DR, et al: Expression and characterization of the cystic fibrosis transmembrane conductance regulator. Nature (Lond) 347:382-386, 1990
10. Jacquot J, Puchelle E, Hinnrasky J, et al: Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur Respir J 6:169-176, 1993
11. Kartner N, Augustinas O, Jensen TJ, Naismith AL: Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland. Nature Genet 1:321-327, 1992
12. 2+ release in Hep G2 human hepatoblastoma cells. Biochem Biophys Res Commun 261:682-688, 1999
13. Kunzelmann K: The cystic fibrosis transmembrane conductance regulator and its function in epithelial transport. Rev Physiol Biochem Pharmacol 137:1-70, 1999
14. Kunzelmann K, Schreiber R: CFTR, a regulatory channel. J Memb Biol 168:1-8, 1999
15. Kuver R, Klinkspoor JH, Osborne W, Lee P: Mucous granule exocytosis and CFTR expression in gallbladder epithelium. Glycobiology 10:149-157, 2000
16. +/glucose cotransporter and CFTR in Caco-2 cells: Relevance to cystic fibrosis. J Cell Physiol 176:472-481, 1998
17. 2+-induced arachidonic acid release by epithelial cells. DNA Cell Biol 16:749-759, 1997
18. Montserrat C, Merten M, Figarella C: Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells. FEBS Lett 16:264-268, 1996
19. Pier GB, Grout M, Zaidi TS: Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung. Proc Natl Acad Sci 94:12088-12093, 1997
20. Pier GB, Grout M, Zaidi T, et al: Salmonella typhi uses CFTR to enter intestinal epithelial cells. Nature 393:79-82, 1998
21. Prince LSA, Tousson A, Marchase RB: Cell surface labeling of CFTR in T84 cells. Am J Physiol 264(Cell Physiol 33):491-C498, 1993
22. Riordan JR, Rommers JM, Kerem B-S, et al: Identification of the cystic fibrosis gene: Cl. Science 245:1066-1073, 1989
23. Rommens J, Iannuzzi MC, Kerem B-S, et al: Identification of the cystic fibrosis gene: Ch. Science 245:1059-1065, 1989
24. - channel protein (CFTR) and its mRNA are expressed in the secretory portion of human eccrine sweat gland. J Histochem Cytochem 48:345-353, 2000
25. Sato K, Sato F: Pharmacologic responsiveness of isolated single eccrine sweat glands. Am J Physiol 240:R44-R51, 1981
26. Sato K, Sato F: Defective β-adrenergic response of cystic fibrosis sweat glands in vivo and in vitro. J Clin Invest 73:1763-1771, 1984
27. Sato K, Kang HW, Saga K, Sato KT: Biology of the eccrine sweat gland. I Mechanism of sweat secretion. J Am Acad Derm 20:537-565, 1989
28. - currents in dissociated eccrine secretory coil cells during stimulation. J Memb Biol 134:93-106, 1993
29. Stanta G, Schneide C: RNA extracted from paraffin-embedded human tissues is amenable to analysis by PCR amplification. Biotechniques 11:304-308, 1991
30. Welsh MJ, Smith AE: Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73:1251-1254, 1993
31. Zehbe I, Hacker GW, Sallstrom JE, Rylander E, Wilander E: Self-sustained sequence replication-based amplification (3SR) for the in situ detection of mRNA in cultured cells. Cellvision 1:20-24, 1994