Role of phosphatidylinositol 3-kinase in the binding of Bordetella pertussis to human monocytes

Cellular Microbiology

Volumn 4, Issue 12, 2002, Pages 825-833

  Ishibashi, Yoshio ^a   Yoshimura, Katsuaki ^a   Nishikawa, Akemi ^a   Claus, Sarah ^b   Laudanna, Carlo ^b   Relman, David A ^b,c  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ARGINYLGLYCYLASPARTIC ACID; BACTERIAL PROTEIN; BETA2 INTEGRIN; CD47 ANTIGEN; COMPLEMENT COMPONENT C3 RECEPTOR; HEMAGGLUTININ; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; WORTMANNIN;

ARTICLE; BACTERIAL INFECTION; BACTERIAL MUTATION; BACTERIUM ADHERENCE; BINDING SITE; BORDETELLA PERTUSSIS; CELL STRAIN; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MONOCYTE; NONHUMAN; PATHOGENESIS; PERTUSSIS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD; ANTIGENS, CD47; BACTERIAL ADHESION; BORDETELLA PERTUSSIS; CARRIER PROTEINS; HEMAGGLUTININS; HUMANS; INTEGRIN ALPHAVBETA3; MACROPHAGE-1 ANTIGEN; MONOCYTES; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION; TYROSINE;

BACTERIA (MICROORGANISMS); BORDETELLA; BORDETELLA PERTUSSIS;

EID: 0036910985     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2002.00235.x     Document Type: Article

References (59)

1. Anderson, S.M., Burton, E.A., and Koch, B.L. (1997) Phosphorylation of Cbl following stimulation with interleukin 3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase. J Biol Chem 272: 739-745.
2. Backer, J.M., Myers, Jr, M.G. Shoelson, S.E. Chin, D.L. Sun, X.J. Miralpeix, M., et al. (1992) Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation. EMBO J 11: 3469-3479.
3. Blystone, S.D., Lindberg, F.P., LaFlamme, S.E., and Brown, E.J. (1995) Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated protein. J Cell Biol 130: 745-754.
4. Boschwitz, J.S., Batanghari, J.W., Kedem, H., and Relman, D.A. (1997) Bordetella pertussis infection of human monocytes inhibits antigen-dependent CD4 T cell proliferation. J Infect Dis 176: 678-686.
5. Brown, E., Hooper, L., Ho, T., and Gresham, H. (1990) Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins. J Cell Biol 111: 2785-2794.
6. 3 integrin and CR3. J Immunol 163: 6078-6085.
7. Carpenter, C.L., and Cantley, L.C. (1996) Phosphoinositide kinases. Curr Opin Cell Biol 8: 153-158.
8. Cherry, J.D., Baraff, L.J., and Hewlett, E. (1989) The past, present, and future of pertussis: The role of adults in epidemiology and future control. West J Med 150: 319-328.
9. Clark, E.A., and Brugge, J.S. (1995) Integrins and signal transduction pathway: the road taken. Science 268: 233-239.
10. Diamond, M.S., and Springer, T.A. (1994) The dynamic regulation of integrin adhesiveness. Curr Biol 4: 506-517.
11. Escobedo, J.A., Navankasattusas, S., Kavanaugh, W.M., Milfay, D., Fried, V.A., and Williams, L.T. (1991) cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor. Cell 65: 75-82.
12. Ferrel, J.E., and Martin, G.S. (1989) Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. Proc Natl Acad Sci USA 86: 2234-2238.
13. Friedman, R.L., Nordensson, K., Wilson, L., Akporiaye, E.T., and Yocum, D.E. (1992) Uptake and intracelluar survival of Bordetella pertussis. human macrophages. Infect Immun 60: 4578-4585.
14. Giancotti, F.G., and Ruoslahti, E. (1999) Integrin signaling. Science 285: 1028-1032.
15. Golden, A., Brugge, J.S., and Shattil, S.J. (1990) Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins. J Cell Biol 111: 3117-3127.
16. Gresham, H.D., Goodwin, J.L., Allen, P.M., Anderson, D.C., and Wright, S.D. (1989) A novel member of the integrin receptor family mediates Arg-Gly-Asp-stimulated neutrophil phagocytosis. J Cell Biol 108: 1935-1943.
17. Gresham, H.D., Adams, S.P., and Brown, E.J. (1992) Ligand binding specificity of the leukocyte response integrin expressed by human nertrophils. J Biol Chem 267: 13895-13902.
18. Ishibashi, Y., Claus, S., and Relman, D.A. (1994) Bordetella pertussis filamentous hemaggulutinin interacts with a leukocyte signal transduction complex and stimulates bacterial adherence to monocyte CR3 (CD11b/CD18). J Exp Med 180: 1225-1233.
19. Jones, S.L., Knaus, U.G., Bokoch, G.M., and Brown, E.J. (1998) Two signaling mechanisms for activation of alphaM beta2 avidity in polymorphonuclear neutrophils. J Biol Chem 273:10556-10566.
20. Kapeller, R., and Cantley, L.C. (1994) Phosphatidylinositol 3-kinase. Bioessays 16: 565-576.
21. Kapeller, R., Prasad, K.V., Janssen, O., Hou, W., Schaffhausen, B.S., Rudd, C.E., and Cantley, L.C. (1994) Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. J Biol Chem 269: 1927-1933.
22. Kashiwagi, H., Schwartz, M.A., Eigenthaler, M., Ginsberg, M.H., and Shattil, S.J. (1997) Affinity modulation of platelet integrin αIIbβ3 by β3-endonexin, a selective binding partner of the β3 integrin cytoplasmic tail. J Cell Biol 137: 1433-1443.
23. Kimura, A., Mountzouros, K.T., Relman, D.A., Falkow, S., and Cowell, J.L. (1990) Bordetella pertussis filamentous hemagglutinin: evaluation as a protective antigen and colonization factor in a mouse respiratory infection model. Infect Immun 58: 7-16.
24. Klippel, A., Reinhard, C., Kavanaugh, W.M., Apell, G., Escobedo, M.A., and Williams, L.T. (1996) Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol Cell Biol 16: 4117-4127.
25. Klipper, A., Escobedo, J.A., Hirano, M., and Williams, L.T. (1994) The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity. Mol Cell Biol 14: 2675-2685.
26. LaFlamme, S.E., Akiyama, S.K., and Yamada, K.M. (1992) Regulation of fibronectin receptor distribution. J Cell Biol 117: 437-442.
27. Li, C.Y., Lam, K.W., and Yam, L.T. (1973) Esterases in human leukocytes. J Histochem Cytochem 21: 1.
28. Li, X., and Earp, H.S. (1997) Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells. J Biol Chem 272: 14341-14348.
29. Lindberg, F.P., Gresham, H.D., Schwarz, E., and Brown, E.J. (1993) Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding. J Cell Biol 123: 485-496.
30. Lindberg, F.P., Lublin, D.M., Telen, M.J., Veile, R.A., Miller, Y.E., Donis, K.H., and Brown, E.J. (1994) Rh-related antigen CD47 is the signal -transducer integrin-associated protein. J Biol Chem 269: 1567-1570.
31. Liu, X., Marengere, L.E.M., Koch, C.A., and Pawson, T. (1993) The v-Src SH3 domain binds phosphatidylinositol 3′-kinase. Mol Cell Biol 13: 5225-5232.
32. Long, S.S., Welkon, C.J., and Clark, J.L. (1990) Widespread silent transmission of pertussis in families: antibody correlates of infection and symptomatology. J Infect Dis 161: 480-486.
33. Marie-Cardine, A., Maridonneau-Parini, I., Ferrer, M., Danielian, S., Rothhut, B., Fagard, R., et al. (1992) The lymphocyte-specific tyrosine protein kinase p56lck is endocytosed in Jurkat cells stimulated via CD2. J Immunol 148: 3879-3884.
34. Meconi, S., Capo, C., Remacle-Bonnet, M., Pommier, G., Raoult, D., and Mege, J.L. (2001) Activation of protein tyrosine kinases by Coxiella burnetii: role in actin cytoskeleton reorganization and bacterial phagocytosis. Infect Immun 69: 2520-2526.
35. Menozzi, F.D., Gantiez, C., and Locht, C. (1991) Interaction of the Bordetella pertussis filamentous hemagglutinin with heparin. FEMS Microbiol Lett 62: 59-64.
36. Nagel, W., Zeitlmann, L., Schilcher, P., Geiger, C., Kolanus, J., and Kolanus, W. (1998) Phosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1. J Biol Chem 273: 14853-15461.
37. Nakamura, S., and Yakamura, H. (1989) Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets. J Biol Chem 264: 7089-7091.
38. Nelson, J.D. (1978) The changing epidemiology of pertussis in young infants: the role of adults as reservoirs of infection. Am J Dis Child 132: 371-373.
39. Otsu, M., Hiles, I., Gout, I., Fry, M.J., Ruiz-Larrea, F., Panayotou, G., et al. (1991) Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase. Cell 65: 91-104.
40. Pavalko, F.M., and LaRoche, S.M. (1993) Activation of human neutrophils induces an interaction between the integrin β2-subunit (CD18) and the actin binding protein alpha-actinin. J Immunol 151: 3795-3807.
41. Pleiman, C.M., Hertz, W.M., and Cambier, J.C. (1994) Activation of phosphatidylinositol-3′ kinase by src-family kinase SH3 binding to the p85 subunit. Science 263: 1609-1612.
42. fyn mediates binding to phosphatidylinositol 3-kinase in T cells. Proc Natl Acad Sci USA 90: 7366-7370.
43. Relman, D.A. (1995) Bordetella pertussis: determinants of virulence. In Handbook of Natural Toxins. Moss, J., Iglewski B., Vaughan M., and Tu A.T. (eds). New York: Marcel Dekker, Vol. 8, 367-405.
44. Relman, D.A., Domenighini, M., Tuomanen, E., Rappuoli, R., and Falkow, S. (1989) Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. Proc Natl Acad Sci USA 86: 2637-2641.
45. Relman, D., Tuomanen, E., Falkow, S., Golenbock, D.T., Saukkonen, K., and Wright, S.D. (1990) Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. Cell 61: 1375-1382.
46. Sato, Y., Cowell, J.L., Sato, H., Burstyn, D.G., and Manclark, C.R. (1983) Separation and purification of the hemagglutinins from Bordetella pertussis. Infect Immun 41: 313-320.
47. Schaller, M.D., Otey, C.A., Hildebrand, J.D., and Parsons, J.T. (1995) Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains. J Cell Biol 130: 1181-1187.
48. Senior, R.M., Gresham, H.D., Griffin, G.L., Brown, E.J., and Chung, A.E. (1992) Entactin stimulates neutrophil adhesion and chemotaxis through interactions between its Arg-Gly-Asp (RGD) domain and the leukocyte response integrin. J Clin Invest 90: 2251-2257.
49. Sharma, C.P., Ezzell, R.M., and Arnaout, M.A. (1995) Direct interaction of filamin (ABP-280) with the β2 integrin subunit CD18. J Immunol 154: 3461-3470.
50. Shimizu, Y., and Hunt, S.W. (1996) Regulating integin-mediated adhesion: one more function for PI3-kinase? Immunol Today 17: 565-573.
51. Sigematsu, H., Iwasaki, H., Otsuka, T., Ohno, Y., Arima, F., and Niho, Y. (1997) Role of the vav proto-oncogene product (Vav) in erythropoietin-mediated cell proliferation and phosphatidylinositol 3-kinase activity. J Biol Chem 272: 14334-14340.
52. Steed, L.L., Setareh, M., and Friedman, R.L. (1991) Intracellular survival of virulent Bordetella pertussis. Human polymorphonuclear leukocytes. J Leukoc Biol 50: 321-330.
53. Susa, M., Rohner, D., and Bichsel, S. (1996) Differences in binding of PI3-kinase to the src-homology domains 2 and 3 of p56 lck and p59 fyn tyrosine kinases. Biochembiophys Res Commun 220: 729-734.
54. Ticchioni, M., Deckert, M., Mary, F., Bernard, G., Brown, E.J., and Bernard, A. (1997) Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells. J Immunol 158: 677-684.
55. Tuomanen, E., and Weiss, A. (1985) Characterization of two adhesins of Bordetella pertussis for human ciliated respiratory-epithelial cells. J Infectdis 152: 118-125.
56. Tuomanen, E., Towbin, H., Rosenfelder, G., Braun, D., Larson, G., Hansson, G.C., and Hill, R. (1988) Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells. J Exp Med 168: 267-277.
57. Weiss, A.A., Hewlett, E.L., Myers, G.A., and Falkow, S. (1983) Tn5-induced mutations affecting virulence factors of Bordetella pertussis. Infect Immun 42: 33-41.
58. Yamada, K.M., and Miyamoto, S. (1995) Integrin transmembrane signaling and cytoskeletal control. Curr Opin Cell Biol 7: 681-689.
59. Zhou, M., and Brown, E.J. (1993) Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst. J Exp Med 178: 1165-1174.