Protein kinase C-mediated desmin phosphorylation is related to myofibril disarray in cardiomyopathic hamster heart

Experimental Biology and Medicine

Volumn 227, Issue 11, 2002, Pages 1039-1046

  Huang, Xupei ^a   Li, Jian ^b   Foster, Dalton ^a   Lemanski, Sharon L ^a   Dube, Dipak K ^c   Zhang, Chi ^a   Lemanski, Larry F ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Cardiac hypertrophy; Cell culture; Intermediate filaments; Myocardium; Myofibril protein

Indexed keywords

DESMIN; PROTEIN KINASE C; TROPONIN I;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HAMSTER; HEART MUSCLE; IMMUNOHISTOCHEMISTRY; MUSCLE FIBRIL; NONHUMAN;

ANIMALS; CARDIOMYOPATHIES; CRICETINAE; DESMIN; MESOCRICETUS; MICROSCOPY, ELECTRON; PHOSPHORYLATION; PROTEIN KINASE C; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS;

EID: 0036908855     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Carlsson L, Thornell LE. Desmin-related myopathies in mice and man. Acta Physiol Scand 171:341-348, 2001.
2. Goebel HH. Desmin-related myopathies. Curr Opin Neurol 10:426-429, 1997.
3. Goebel HH, Warlo IA. Progress in desmin-related myopathies. J Child Neurol 15:565-572, 2000.
4. Dalakas MC, Park KY, Semino-Moca C, Lee HS, Sivakumar K, Goldfarb LG. Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene. N Engl J Med 342:770-780, 2000.
5. Rappaport L, Contard F, Samuel JL, Delcayce C, Marotte F, Tome F, Fardeau M. Storage of phosphorylated desmin in a familial myopathy. FEBS Lett 231:421-425, 1988.
6. Homburger F, Nixon CW, Eppenberger M, Baker JR. Hereditary myopathy in the Syrian hamster: Studies on pathogenesis. Ann N Y Acad Sci 138:14-27, 1966.
7. Wrogemann K, Nylen EG. Mitochondrial calcium overloading in cardiomyopathic hamster. J Mol Cell Cardiol 10:185-195, 1978.
8. Ferrans VJ, Morrow AG, Roberts WC. Myocardial ultrastructure in idiopathic hypertrophic subaortic stenosis. Circulation 45:769-792, 1972.
9. Thornell LE, Carlsson L, Li Z, Mericskay M, Paulin D. Null mutation in the desmin gene gives rise to a cardiomyopathy. J Mol Cell Cardiol 29:2107-2124, 1997.
10. Wang J, Liu X, Arneja AS, Dhalla NS. Alterations in protein kinase A and protein kinase C levels in heart failure due to genetic cardiomyopathy. Can J Cardiol 15:683-690, 1999.
11. 2+-sensitive isoforms in the failing human heart. Circulation 99:384-391, 1999.
12. Kitamura S, Ando S, Shibata M, Tanabe K, Sato C, Inagaki M. Protein kinase C phosphorylation of desmin at four serine residues within the non-α-helical domain. J Biol Chem 264:5674-5678, 1989.
13. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci U S A 76:4350-4354, 1979.
14. Huang XP, Pi YQ, Lokuta AJ, Greaser ML, Walker JW. Arachidonic acid stimulates protein kinase C-ε redistribution in heart cells. J Cell Science 110:1625-1634, 1997.
15. Granger BL, Lazarides E. The existence of an insoluble Z disc scaffold in chicken skeletal muscle. Cell 15:1253-1268, 1978.
16. Ariza A, Coll J, Fernandez-Figueras T, Lopea D, Mate JL, Garcia O, Fernandez-Vasalo A, Navas-Palacios JJ. Desmin myopathy: A multi-system disorder involving skeletal, cardiac, and smooth muscle. Human Pathol 26:1032-1037, 1995.
17. Campbell GR, Shamley-Campbell J, Groschel-Strewart V, Small JV, Anderson P. Antibody staining of 10-nm (100-Å) filament in cultured smooth, cardiac and skeletal muscle cells. J Cell Sci 37:303-322, 1979.
18. Lazarides E. The distribution of desmin (100Å) filaments in primary cultures of embryonic chicken cardiac cells. Exp Cell Res 112:256-273, 1978.
19. Saetersdal T, Dalen H, Roli J. Immunofluorescent and immunogold electron microscopy of desmin in isolated adult heart myocytes of the rat. Histochem 92:467-473, 1989.
20. Tokuyasu KT, Dutton AH, Singer SJ. Immunoelectron microscopic studies of desmin (skeletin) localization and intermediate filament organization in chicken cardiac muscle. J Cell Biol 96:1736-1742, 1983.
21. Ip W, Spencer DI, Fischmen DA. Detection of desmin-containing intermediate filaments in cultured muscle and nonmuscle cells by immunoelectron microscopy. J Cell Biol 96:401-408, 1983.
22. Evans RM. The intermediate filament proteins vimentin and desmin are phosphorylated in specific domains. Eur J Cell Biol 46:152-160, 1988.
23. Inagaki M, Nishi Y, Nishizawa K, Matsuyama M, Sato C. Site-specific phosphorylation induces disassembly of vimentin filaments in vitro. Nature 328:649-652, 1987.
24. Heling A, Zimmermann R, Kostin S, Maeno Y, Hein S, Devaux B, Bauer E, Klovekom W, Schlepper M, Schaper W, Schaper J. Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium. Circ Res 86:846-853, 2000.
25. Stoeckel ME, Osborn M, Porte A, Sarez A, Batzenchlager A, Weber K. An unusual familial cardiomyopathy characterized by aberrant accumulations of desmin-type intermediate filaments. Virchows Arch 393:53-60, 1981.
26. Lemanski LF, Tu ZH. Immunofluorescent studies for myosin, actin, tropomyosin and α-actinin in cultured cardiomyopathic hamster heart cells. Dev Biol 97:338-348, 1983.