Hosting for the cruel and the inconsequential

Nature Medicine

Volumn 8, Issue 12, 2002, Pages 1349-1350

  Normark, Birgitta Henriques ^a   Normark, Staffan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA; HLA ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

BACTERIAL COLONIZATION; BACTERIAL INFECTION; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNE SYSTEM; MULTIPLE ORGAN FAILURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SALMONELLA; SHORT SURVEY; STREPTOCOCCUS GROUP A; STREPTOCOCCUS INFECTION; TOXIC SHOCK SYNDROME;

GENES, MHC CLASS II; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; POLYMORPHISM, GENETIC; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; SALMONELLA; STREPTOCOCCUS; STREPTOCOCCUS SP. 'GROUP A';

EID: 0036908501     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1202-1349     Document Type: Short Survey

References (11)

1. Bochicchio, G.V., Joshi, M., Joshi, M., Henry, S. & Scalea, T. Group A Streptococcus (GAS) soft-tissue infections: A lethal organism on the rise. Am. Surg. 67, 1089-1092 (2001).
2. Kotb, M. et al. An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections. Nature Med. 8, 1398-1404 (2002).
3. Norrby-Teglund, A. et al. Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection. Eur. J. Immunol. 30, 3247-3255 (2000).
4. Hidalgo-Grass, C. et al. A locus of group A streptococcus involved in invasive disease and DNA transfer. Mol. Microbiol. 46, 87-99 (2002).
5. Proft, T. et al. The streptococcal superantigen SMEZ exhibits wide allelic variation, mosaic structure, and significant antigenic variation. J. Exp. Med. 191, 1765-1776 (2000).
6. Nizet, V. et al. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature. 414, 454-457 (2001).
7. Pütsep, K., Carlsson, G., Boman, H.G. & Andersson, M. Deficiency of antibacterial peptides in patients with morbus Kostmann: An observation study. Lancet 360, 1144-1149 (2002).
8. Baker, M., Gutman, D.M., Papageorgiou, A.C., Collins, C.M. & Acharya, K.R. Structural features of a zinc binding site in the superantigen strepococcal pyrogenic exotoxin A (SpeA1): Implications for MHC class II recognition. Protein Sci. 10, 1268-1273 (2001).
9. Papageorgiou, A.C. et al. Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. EMBO J. 18, 9-21 (1999).
10. Sundberg, E.J. et al. Structures of two streptococcal superantigens bound to TCR β chains reveal diversity in the architecture of T cell signaling complexes. Structure (Camb). 10, 687-699 (2002).
11. Welcher, B.C. et al. Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: Implications for development of vaccines and therapeutics. J. Infect. Dis. 186, 501-510 (2002).