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0003458664
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K. Drauz, & H. Waldmann. Weinheim: Wiley-VCH
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Drauz K., Waldmann H. Enzyme Catalysis in Organic Chemistry. 2002;Wiley-VCH, Weinheim.
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(2002)
Enzyme Catalysis in Organic Chemistry
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2
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0036525715
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Oxidative biotransformations using oxygenases
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Recent developments in biotransformations with oxygenases including nonactivated carbon, benzylic, allylic and aromatic hydroxylations are reviewed.
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Li Z., van Beilen J., Duetz W.A., Schmid A., de Raadt A., Griengl H., Witholt B. Oxidative biotransformations using oxygenases. Curr Opin Chem Biol. 6:2002;136-144. Recent developments in biotransformations with oxygenases including nonactivated carbon, benzylic, allylic and aromatic hydroxylations are reviewed.
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(2002)
Curr Opin Chem Biol
, vol.6
, pp. 136-144
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Li, Z.1
Van Beilen, J.2
Duetz, W.A.3
Schmid, A.4
De Raadt, A.5
Griengl, H.6
Witholt, B.7
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3
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0033635584
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Enzymatic hydroxylation reactions
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A review dealing with various aspects of enzymatic hydroxylation reactions including new synthetic targets, new processes and mechanistic studies.
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Holland H.L., Weber H.K. Enzymatic hydroxylation reactions. Curr Opin Biotechnol. 11:2000;547-553. A review dealing with various aspects of enzymatic hydroxylation reactions including new synthetic targets, new processes and mechanistic studies.
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(2000)
Curr Opin Biotechnol
, vol.11
, pp. 547-553
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Holland, H.L.1
Weber, H.K.2
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4
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0036525713
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Protein engineering of oxygenases for biocatalysis
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The scope and limitations of protein engineering in monooxygenase, dioxygenase and chloroperoxidase enzyme improvement are reviewed.
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Cirino P.C., Arnold F.H. Protein engineering of oxygenases for biocatalysis. Curr Opin Chem Biol. 6:2002;130-135. The scope and limitations of protein engineering in monooxygenase, dioxygenase and chloroperoxidase enzyme improvement are reviewed.
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(2002)
Curr Opin Chem Biol
, vol.6
, pp. 130-135
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Cirino, P.C.1
Arnold, F.H.2
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5
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0033578652
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The concept of docking/protecting groups in biohydroxylation
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The docking/protecting group concept is introduced and brief examples of its application given, namely the hydroxylation of ketones, carboxylic acids, aldehydes and alcohols.
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Braunegg G., de Raadt A., Feichtenhofer S., Griengl H., Kopper I., Lehmann A., Weber H.J. The concept of docking/protecting groups in biohydroxylation. Angew Chem Int Ed Engl. 38:1999;2763-2766. The docking/protecting group concept is introduced and brief examples of its application given, namely the hydroxylation of ketones, carboxylic acids, aldehydes and alcohols.
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(1999)
Angew Chem Int Ed Engl
, vol.38
, pp. 2763-2766
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Braunegg, G.1
De Raadt, A.2
Feichtenhofer, S.3
Griengl, H.4
Kopper, I.5
Lehmann, A.6
Weber, H.J.7
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6
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0035808421
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The concept of docking and protecting groups in biohydroxylation
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The docking/protecting group concept is covered in more detail for the hydroxylation of four different substance classes commonly used in preparative organic chemistry: ketones, alcohols, aldehydes and carboxylic acids.
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de Raadt A., Griengl H., Weber H.J. The concept of docking and protecting groups in biohydroxylation. Chem Eur J. 7:2001;27-31. The docking/protecting group concept is covered in more detail for the hydroxylation of four different substance classes commonly used in preparative organic chemistry: ketones, alcohols, aldehydes and carboxylic acids.
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(2001)
Chem Eur J
, vol.7
, pp. 27-31
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De Raadt, A.1
Griengl, H.2
Weber, H.J.3
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7
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0030065772
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Microbial hydroxylation of 2-cycloalkylbenzoxazoles. Part I. Product spectrum obtained from Cunninghamella blakesleeana DSM 1906 and Bacillus megaterium DSM 32
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de Raadt A., Griengl H., Petsch M., Plachota P., Schoo N., Weber H.J., Braunegg G., Kopper I., Kreiner M., Zeiser A., Kieslich K. Microbial hydroxylation of 2-cycloalkylbenzoxazoles. Part I. Product spectrum obtained from Cunninghamella blakesleeana DSM 1906 and Bacillus megaterium DSM 32. Tetrahedron Asymmetry. 7:1996;467-472.
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(1996)
Tetrahedron Asymmetry
, vol.7
, pp. 467-472
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De Raadt, A.1
Griengl, H.2
Petsch, M.3
Plachota, P.4
Schoo, N.5
Weber, H.J.6
Braunegg, G.7
Kopper, I.8
Kreiner, M.9
Zeiser, A.10
Kieslich, K.11
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8
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0034068350
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Optimization of the hydroxylation of 2-cyclopentylbenzoxazole with Cunninghamella blakesleeana DSMZ 1906
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Kraemer-Schafhalter A., Domenek S., Boehling H., Feichtenhofer S., Griengl H., Voss H. Optimization of the hydroxylation of 2-cyclopentylbenzoxazole with Cunninghamella blakesleeana DSMZ 1906. Appl Microbiol Biotechnol. 53:2000;266-271.
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(2000)
Appl Microbiol Biotechnol
, vol.53
, pp. 266-271
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Kraemer-Schafhalter, A.1
Domenek, S.2
Boehling, H.3
Feichtenhofer, S.4
Griengl, H.5
Voss, H.6
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9
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0035931531
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Microbial hydroxylation of unsaturated, cyclic carboxylic acids protected as benzoxazoles
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de Raadt A., Feichtenhofer S., Griengl H., Klingler M.F., Weber H. Microbial hydroxylation of unsaturated, cyclic carboxylic acids protected as benzoxazoles. J Mol Cat B: Enzym. 11:2001;361-366.
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(2001)
J Mol Cat B: Enzym
, vol.11
, pp. 361-366
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De Raadt, A.1
Feichtenhofer, S.2
Griengl, H.3
Klingler, M.F.4
Weber, H.5
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10
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0033674514
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Chiral auxiliaries as docking/protecting groups in biohydroxylation: The hydroxylation of enantiopure spirooxazolidines derived from cyclopentanone using Beauveria bassiana ATCC 7159
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de Raadt A, Fetz B, Griengl H, Klingler MF, Kopper I, Krenn B, Münzer DF, Ott RG, Plachota P, Weber HJ et al.: Chiral auxiliaries as docking/protecting groups in biohydroxylation: The hydroxylation of enantiopure spirooxazolidines derived from cyclopentanone using Beauveria bassiana ATCC 7159. Eur J Org Chem 2000, 3835-3847. For the first time chiral auxiliaries were used as docking/protecting groups in the biohydroxylation of cyclopentanone to improve product de and yield.
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(2000)
Eur J Org Chem
, pp. 3835-3847
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De Raadt, A.1
Fetz, B.2
Griengl, H.3
Klingler, M.F.4
Kopper, I.5
Krenn, B.6
Münzer, D.F.7
Ott, R.G.8
Plachota, P.9
Weber, H.J.10
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11
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17944376999
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Chiral auxiliaries as docking/protecting groups: Biohydroxylation of selected ketones with Beauveria bassiana ATCC 7159
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de Raadt A., Fetz B., Griengl H., Klingler M.F., Krenn B., Mereiter K., Münzer D.F., Plachota P., Weber H.J., Saf R. Chiral auxiliaries as docking/protecting groups: biohydroxylation of selected ketones with Beauveria bassiana ATCC 7159. Tetrahedron. 57:2001;8151-8157.
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(2001)
Tetrahedron
, vol.57
, pp. 8151-8157
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De Raadt, A.1
Fetz, B.2
Griengl, H.3
Klingler, M.F.4
Krenn, B.5
Mereiter, K.6
Münzer, D.F.7
Plachota, P.8
Weber, H.J.9
Saf, R.10
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12
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0037012874
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Selectivity of biohydroxylation with Beauveria bassiana of trans-2-fluorocycloalkyl N-phenylcarbamates
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Haufe G., Wölker D., Fröhlich R. Selectivity of biohydroxylation with Beauveria bassiana of trans-2-fluorocycloalkyl N-phenylcarbamates. J Org Chem. 67:2002;3022-3028.
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(2002)
J Org Chem
, vol.67
, pp. 3022-3028
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Haufe, G.1
Wölker, D.2
Fröhlich, R.3
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13
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0035861695
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Preparation of (R)- and (S)-N-protected 3-hydroxypyrrolidines by hydroxylation with Sphingomonas sp. HXN-200, a highly active, regio- and stereoselective, and easy to handle biocatalyst
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Resting as well as frozen/thawed Sphingomonas sp. cells were used to regio- and stereoselectively hydroxylate N-substituted pyrrolidine derivatives. The configuration of the hydroxylated product could be determined by the choice of N-substituent.
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Li Z., Feiten H.J., Chang D., Duetz W.A., van Beilen J.B., Witholt B. Preparation of (R)- and (S)-N-protected 3-hydroxypyrrolidines by hydroxylation with Sphingomonas sp. HXN-200, a highly active, regio- and stereoselective, and easy to handle biocatalyst. J Org Chem. 66:2001;8424-8430. Resting as well as frozen/thawed Sphingomonas sp. cells were used to regio- and stereoselectively hydroxylate N-substituted pyrrolidine derivatives. The configuration of the hydroxylated product could be determined by the choice of N-substituent.
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(2001)
J Org Chem
, vol.66
, pp. 8424-8430
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Li, Z.1
Feiten, H.J.2
Chang, D.3
Duetz, W.A.4
Van Beilen, J.B.5
Witholt, B.6
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14
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0037198750
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Practical syntheses of N-substituted 3-hydroxyazetidines and 4-hydroxypiperidines by hydroxylation with Sphingomonas sp. HXN-200
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Frozenthawed Sphingomonas sp. HXN-200 cells were used to regioselectively hydroxylate N-substituted azetidine and piperidine derivatives in high yields. For the first time, rehydrated lyophilized cells could also be used.
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Chang D., Feiten H.J., Engesser K.H., van Beilen J.B., Witholt B., Li Z. Practical syntheses of N-substituted 3-hydroxyazetidines and 4-hydroxypiperidines by hydroxylation with Sphingomonas sp. HXN-200. Org Lett. 4:2002;1859-1862. Frozenthawed Sphingomonas sp. HXN-200 cells were used to regioselectively hydroxylate N-substituted azetidine and piperidine derivatives in high yields. For the first time, rehydrated lyophilized cells could also be used.
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(2002)
Org Lett
, vol.4
, pp. 1859-1862
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Chang, D.1
Feiten, H.J.2
Engesser, K.H.3
Van Beilen, J.B.4
Witholt, B.5
Li, Z.6
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15
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0034736384
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Preparation of (S)-N-substituted 4-hydroxy-pyrrolidin-2-ones by regio- and stereoselective hydroxylation with Sphingomonas sp. HXN-200
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Chang D., Witholt B., Li Z. Preparation of (S)-N-substituted 4-hydroxy-pyrrolidin-2-ones by regio- and stereoselective hydroxylation with Sphingomonas sp. HXN-200. Org Lett. 2:2000;3949-3952.
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(2000)
Org Lett
, vol.2
, pp. 3949-3952
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Chang, D.1
Witholt, B.2
Li, Z.3
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16
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0035968393
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Enzymatic asymmetric hydroxylation of unnatural substrates with soybean lipoxygenase
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With the aid of substrate engineering, unnatural substrates could be hydroxylated employing soybean lipoxygenase and a chemical reduction.
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Yadav J.S., Nanda S., Bhaskar Rao A. Enzymatic asymmetric hydroxylation of unnatural substrates with soybean lipoxygenase. Tetrahedron Asymmetry. 12:2001;2129-2135. With the aid of substrate engineering, unnatural substrates could be hydroxylated employing soybean lipoxygenase and a chemical reduction.
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(2001)
Tetrahedron Asymmetry
, vol.12
, pp. 2129-2135
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Yadav, J.S.1
Nanda, S.2
Bhaskar Rao, A.3
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17
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0034987387
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Soybean lipoxygenase and horseradish peroxidase catalysed asymmetric oxidation-reduction sequence for the synthesis of chiral (Z,E) diene-diols
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Yadav JS, Nanda S, Bhaskar Rao A: Soybean lipoxygenase and horseradish peroxidase catalysed asymmetric oxidation-reduction sequence for the synthesis of chiral (Z,E) diene-diols. Synlett 2001, 787-788.
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(2001)
Synlett
, pp. 787-788
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Yadav, J.S.1
Nanda, S.2
Bhaskar Rao, A.3
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