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Volumn 34, Issue 6, 2002, Pages 379-389

Insulin delivery systems: Present trends and the future direction

Author keywords

Diabetes; Inhalation; Insulin delivery systems; Insulin pump; Stem cell

Indexed keywords

1 VINYL 2 PYRROLIDINONE; 3 SULFOPROPYL ACRYLIC ACID; ACRYLAMIDE; BOVINE INSULIN; CONCANAVALIN A; GLUCOSE; GLUCOSE OXIDASE; INSULIN; INSULIN DERIVATIVE; INSULIN LISPRO; INSULIN ZINC SUSPENSION; MACROGOL; MONOMER; N,N DIMETHYLAMINOETHYL METHACRYLATE POLYMER; POLYMACON; POLYMER; POTASSIUM SALT; TETRAETHYLENE GLYCOL DIMETHACRYLATE POLYMER; UNCLASSIFIED DRUG;

EID: 0036900745     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (19)

References (66)
  • 1
    • 0023772274 scopus 로고
    • Basal rate subcutaneous insulin infusion: Absorption kinetics and relation to local blood flow
    • Hildebrandt P, Birch K. Basal rate subcutaneous insulin infusion: Absorption kinetics and relation to local blood flow. Diabet Med 1988;5:434-40.
    • (1988) Diabet Med , vol.5 , pp. 434-440
    • Hildebrandt, P.1    Birch, K.2
  • 2
    • 0031784896 scopus 로고    scopus 로고
    • Variability of the metabolic effect of soluble insulin and the rapid-acting insulin analog insulin aspart
    • Heinemann L, Weyer C, Rauhaus M, Heinrichs S, Heise T. Variability of the metabolic effect of soluble insulin and the rapid-acting insulin analog insulin aspart. Diabetes Care 1998;21:1910-4.
    • (1998) Diabetes Care , vol.21 , pp. 1910-1914
    • Heinemann, L.1    Weyer, C.2    Rauhaus, M.3    Heinrichs, S.4    Heise, T.5
  • 4
    • 0027370108 scopus 로고
    • Diabetes Control and Complications Trial (DCCT): The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus
    • DCCT Research Group. Diabetes Control and Complications Trial (DCCT): The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. N Engl J Med 1993;329:977-86.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 5
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 6
    • 0032958316 scopus 로고    scopus 로고
    • Epidemiology of Diabetes Interventions and Complications (EDIC): Design, implementation and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort
    • Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group. Epidemiology of Diabetes Interventions and Complications (EDIC): Design, implementation and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort. Diabetes Care 1999;22:99-111.
    • (1999) Diabetes Care , vol.22 , pp. 99-111
  • 7
    • 0035659983 scopus 로고    scopus 로고
    • Insulin therapy: Optimizing control in type 1 and type 2 diabetes
    • Rosenstock J. Insulin therapy: Optimizing control in type 1 and type 2 diabetes. Clin Cornerstone 2001;4:50-64.
    • (2001) Clin Cornerstone , vol.4 , pp. 50-64
    • Rosenstock, J.1
  • 8
    • 0034968761 scopus 로고    scopus 로고
    • Physiological insulin replacement in type 1 diabetes mellitus
    • Bolli GB. Physiological insulin replacement in type 1 diabetes mellitus. Exp Clin Endocrinol Diabetes 2001;109(Suppl 2):317-32.
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , Issue.SUPPL. 2 , pp. 317-332
    • Bolli, G.B.1
  • 9
    • 0026680661 scopus 로고
    • Why intraperitoneal delivery of insulin with implantable pumps in NIDDM?
    • Duckworth WC, Saudek CD, Henry RR. Why intraperitoneal delivery of insulin with implantable pumps in NIDDM? Diabetes 1992;41:657-61.
    • (1992) Diabetes , vol.41 , pp. 657-661
    • Duckworth, W.C.1    Saudek, C.D.2    Henry, R.R.3
  • 10
    • 0033949070 scopus 로고    scopus 로고
    • Mechanisms for weight gain during blood glucose normalization
    • Laville M, Andreelli F. Mechanisms for weight gain during blood glucose normalization. Diabetes Metab 2000;26(Suppl 3):42-5.
    • (2000) Diabetes Metab , vol.26 , Issue.SUPPL. 3 , pp. 42-45
    • Laville, M.1    Andreelli, F.2
  • 11
    • 0031897505 scopus 로고    scopus 로고
    • Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity
    • Steil GM, Rebrin K, Mittelman SD, Bergman RN. Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes 1998;47:714-20.
    • (1998) Diabetes , vol.47 , pp. 714-720
    • Steil, G.M.1    Rebrin, K.2    Mittelman, S.D.3    Bergman, R.N.4
  • 13
    • 0029586806 scopus 로고
    • Symptoms, hormones and glucose fluxes during a gradual hypoglycaemia induced by intraperitoneal vs venous insulin infusion in type 1 diabetes
    • Selam JL, Medlej R, M'Bemba J. Symptoms, hormones and glucose fluxes during a gradual hypoglycaemia induced by intraperitoneal vs venous insulin infusion in type 1 diabetes. Diabet Med 1995;12:1102-9.
    • (1995) Diabet Med , vol.12 , pp. 1102-1109
    • Selam, J.L.1    Medlej, R.2    M'Bemba, J.3
  • 14
    • 0025182886 scopus 로고
    • Devices for insulin administration
    • Selam JL, Charles MA. Devices for insulin administration. Diabetes Care 1990;13:955-79.
    • (1990) Diabetes Care , vol.13 , pp. 955-979
    • Selam, J.L.1    Charles, M.A.2
  • 15
    • 0021341879 scopus 로고
    • Mortality among diabetic patients using continuous subcutaneous insulin-infusion pumps
    • Teutsch SM, Herman WH, Dwyer DM. Mortality among diabetic patients using continuous subcutaneous insulin-infusion pumps. N Engl J Med 1984;310:361-8.
    • (1984) N Engl J Med , vol.310 , pp. 361-368
    • Teutsch, S.M.1    Herman, W.H.2    Dwyer, D.M.3
  • 16
    • 0035656148 scopus 로고    scopus 로고
    • Use of insulin pumps in pregnancies complicated by type 2 diabetes and gestational diabetes in a multiethnic community
    • Simmons D, Thompson CF, Conroy C, Scott DJ. Use of insulin pumps in pregnancies complicated by type 2 diabetes and gestational diabetes in a multiethnic community. Diabetes Care 2001;24:2078-82.
    • (2001) Diabetes Care , vol.24 , pp. 2078-2082
    • Simmons, D.1    Thompson, C.F.2    Conroy, C.3    Scott, D.J.4
  • 17
    • 0034746477 scopus 로고    scopus 로고
    • Continuous subcutaneous insulin infusion therapy for children and adolescents: An option for routine diabetes care
    • Maniatis AK, Klingensmith GJ, Slover RH, Mowry CJ, Chase HP. Continuous subcutaneous insulin infusion therapy for children and adolescents: An option for routine diabetes care. Pediatrics 2001;107:351-6.
    • (2001) Pediatrics , vol.107 , pp. 351-356
    • Maniatis, A.K.1    Klingensmith, G.J.2    Slover, R.H.3    Mowry, C.J.4    Chase, H.P.5
  • 19
    • 0028118561 scopus 로고
    • Normalization of lipoprotein composition by intraperitoneal insulin in IDDM. Role of increased hepatic lipase activity
    • Ruotolo G, Parlavecchia M, Taskinen MR, Galimberti G, Zoppo A, Le NA, et al. Normalization of lipoprotein composition by intraperitoneal insulin in IDDM. Role of increased hepatic lipase activity. Diabetes Care 1994;17:6-12.
    • (1994) Diabetes Care , vol.17 , pp. 6-12
    • Ruotolo, G.1    Parlavecchia, M.2    Taskinen, M.R.3    Galimberti, G.4    Zoppo, A.5    Le, N.A.6
  • 20
    • 0034972854 scopus 로고    scopus 로고
    • External and implantable insulin pumps: Current place in the treatment of diabetes
    • Selam JL. External and implantable insulin pumps: Current place in the treatment of diabetes. Exp Clin Endocrinol Diabetes 2001;109(Suppl 2):333-40.
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , Issue.SUPPL. 2 , pp. 333-340
    • Selam, J.L.1
  • 21
    • 0035443244 scopus 로고    scopus 로고
    • Beneficial effects of continuous subcutaneous insulin infusion in older patients with long-standing type 1 diabetes
    • Rizvi AA, Petry R, Arnold MB, Chakraborty M. Beneficial effects of continuous subcutaneous insulin infusion in older patients with long-standing type 1 diabetes. Endocr Pract 2001;7:364-9.
    • (2001) Endocr Pract , vol.7 , pp. 364-369
    • Rizvi, A.A.1    Petry, R.2    Arnold, M.B.3    Chakraborty, M.4
  • 22
  • 23
    • 0036518602 scopus 로고    scopus 로고
    • Continuous subcutaneous insulin infusion at 25 years: Evidence base for the expanding use of insulin pump therapy in type 1 diabetes
    • Pickup J, Keen H. Continuous subcutaneous insulin infusion at 25 years: Evidence base for the expanding use of insulin pump therapy in type 1 diabetes. Diabetes Care 2002;25:593-8.
    • (2002) Diabetes Care , vol.25 , pp. 593-598
    • Pickup, J.1    Keen, H.2
  • 24
    • 0034998607 scopus 로고    scopus 로고
    • Insulin pumps and glucose regulation
    • Thompson JS, Duckworth WC. Insulin pumps and glucose regulation. World J Surg 2001;25:523-6.
    • (2001) World J Surg , vol.25 , pp. 523-526
    • Thompson, J.S.1    Duckworth, W.C.2
  • 25
    • 0032436616 scopus 로고    scopus 로고
    • Surgical experience with implantable insulin pumps. Department of Veterans Affairs Implantable Insulin Pump Study Group
    • Thompson JS, Duckworth WC, Saudek CD, Giobbie-Hurder A. Surgical experience with implantable insulin pumps. Department of Veterans Affairs Implantable Insulin Pump Study Group. Am J Surg 1998;176:622-6.
    • (1998) Am J Surg , vol.176 , pp. 622-626
    • Thompson, J.S.1    Duckworth, W.C.2    Saudek, C.D.3    Giobbie-Hurder, A.4
  • 26
    • 0035145198 scopus 로고    scopus 로고
    • Macrophage activation in type 1 diabetic patients with catheter obstruction during peritoneal insulin delivery with an implantable pump
    • Kessler L, Tritschler S, Bohbot A, Sigrist S, Karsten V, Boivin S, et al. Macrophage activation in type 1 diabetic patients with catheter obstruction during peritoneal insulin delivery with an implantable pump. Diabetes Care 2001;24:302-7.
    • (2001) Diabetes Care , vol.24 , pp. 302-307
    • Kessler, L.1    Tritschler, S.2    Bohbot, A.3    Sigrist, S.4    Karsten, V.5    Boivin, S.6
  • 27
    • 0034936797 scopus 로고    scopus 로고
    • A randomized study comparing blood glucose control and risk of severe hypoglycemia achieved by non-programmable versus programmable external insulin pumps
    • Catargi B, Breilh D, Gin H, Rigalleau V, Saux MC, Roger P, et al. A randomized study comparing blood glucose control and risk of severe hypoglycemia achieved by non-programmable versus programmable external insulin pumps. Diabetes Metab 2001;27:323-7.
    • (2001) Diabetes Metab , vol.27 , pp. 323-327
    • Catargi, B.1    Breilh, D.2    Gin, H.3    Rigalleau, V.4    Saux, M.C.5    Roger, P.6
  • 28
    • 0035834259 scopus 로고    scopus 로고
    • Modulated insulin delivery from glucose-sensitive hydrogel dosage forms
    • Kim JJ, Park K. Modulated insulin delivery from glucose-sensitive hydrogel dosage forms. J Control Release 2001;77:39-47.
    • (2001) J Control Release , vol.77 , pp. 39-47
    • Kim, J.J.1    Park, K.2
  • 29
    • 0034117192 scopus 로고    scopus 로고
    • Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions
    • Traitel T, Cohen Y, Kost J. Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions. Biomaterials 2001;21:1679-87.
    • (2000) Biomaterials , vol.21 , pp. 1679-1687
    • Traitel, T.1    Cohen, Y.2    Kost, J.3
  • 30
    • 0027972645 scopus 로고
    • Biochemical and morphocytochemical evidence for intestinal absorption of insulin in control and diabetic rats, comparison between the effectiveness of duodenal and colon mucosa
    • Bendayan M, Ziv E, Gingras D. Biochemical and morphocytochemical evidence for intestinal absorption of insulin in control and diabetic rats, comparison between the effectiveness of duodenal and colon mucosa. Diabetologia 1994;37:119-126.
    • (1994) Diabetologia , vol.37 , pp. 119-126
    • Bendayan, M.1    Ziv, E.2    Gingras, D.3
  • 31
    • 0030990091 scopus 로고    scopus 로고
    • The oligopeptide transporter (Pept-1) in human intestine: Biology and function
    • Adibi SA. The oligopeptide transporter (Pept-1) in human intestine: Biology and function. Gastroenterology 1997;113:332-40.
    • (1997) Gastroenterology , vol.113 , pp. 332-340
    • Adibi, S.A.1
  • 32
    • 0034526251 scopus 로고    scopus 로고
    • Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo
    • Ma XY, Pan GM, Lu Z, Hu JS, Bei JZ, Jia JH, et al. Preliminary study of oral polylactide microcapsulated insulin in vitro and in vivo. Diabetes Obes Metab 2000;2:243-50.
    • (2000) Diabetes Obes Metab , vol.2 , pp. 243-250
    • Ma, X.Y.1    Pan, G.M.2    Lu, Z.3    Hu, J.S.4    Bei, J.Z.5    Jia, J.H.6
  • 33
    • 0033934721 scopus 로고    scopus 로고
    • Lipoinsulin encapsulated alginate-chitosan capsules: Intestinal delivery in diabetic rats
    • Ramadas M, Paul W, Dileep KJ, Anitha Y, Sharma CP. Lipoinsulin encapsulated alginate-chitosan capsules: Intestinal delivery in diabetic rats. J Microencapsul 2000;17:405-11.
    • (2000) J Microencapsul , vol.17 , pp. 405-411
    • Ramadas, M.1    Paul, W.2    Dileep, K.J.3    Anitha, Y.4    Sharma, C.P.5
  • 34
    • 0033982973 scopus 로고    scopus 로고
    • Orally administered, insulin-loaded amidated pectin hydrogel beads sustain plasma concentrations of insulin in streptozotocin-diabetic rats
    • Musabayane CT, Munjeri O, Bwititi P, Osim EE. Orally administered, insulin-loaded amidated pectin hydrogel beads sustain plasma concentrations of insulin in streptozotocin-diabetic rats. J Endocrinol 2000;164:1-6.
    • (2000) J Endocrinol , vol.164 , pp. 1-6
    • Musabayane, C.T.1    Munjeri, O.2    Bwititi, P.3    Osim, E.E.4
  • 36
    • 0025752856 scopus 로고
    • Controlled delivery of diphtheria toxoid using biodegradable poly (O, L-Lactide) microcapsules
    • Singh M, Singh A, Talwar GP. Controlled delivery of diphtheria toxoid using biodegradable poly (O, L-Lactide) microcapsules. Pharmacol Res 1991;8:958-61.
    • (1991) Pharmacol Res , vol.8 , pp. 958-961
    • Singh, M.1    Singh, A.2    Talwar, G.P.3
  • 37
    • 0035719828 scopus 로고    scopus 로고
    • The lung as a route for systemic delivery of therapeutic proteins and peptides
    • Agu RU, Ugwoke MI, Armand M, Kinget R, Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res 2001;2:198-209.
    • (2001) Respir Res , vol.2 , pp. 198-209
    • Agu, R.U.1    Ugwoke, M.I.2    Armand, M.3    Kinget, R.4    Verbeke, N.5
  • 38
    • 0035458867 scopus 로고    scopus 로고
    • Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: A randomized controlled trial
    • Gerber RA, Cappelleri JC, Kourides IA, Gelfand RA. Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: A randomized controlled trial. Diabetes Care 2001;24:1556-9.
    • (2001) Diabetes Care , vol.24 , pp. 1556-1559
    • Gerber, R.A.1    Cappelleri, J.C.2    Kourides, I.A.3    Gelfand, R.A.4
  • 39
    • 0035798916 scopus 로고    scopus 로고
    • Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomised proof-of-concept study
    • Skyler JS, Cefalu WT, Kourides IA, Landschulz WH, Balagtas CC, Cheng SL, et al. Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomised proof-of-concept study. Lancet 2001;357:331-5.
    • (2001) Lancet , vol.357 , pp. 331-335
    • Skyler, J.S.1    Cefalu, W.T.2    Kourides, I.A.3    Landschulz, W.H.4    Balagtas, C.C.5    Cheng, S.L.6
  • 40
    • 0033781517 scopus 로고    scopus 로고
    • Viewpoint: Stability of insulin in tropical countries
    • Gill GV. Viewpoint: Stability of insulin in tropical countries. Trop Med Int Health 2000;5:666-7.
    • (2000) Trop Med Int Health , vol.5 , pp. 666-667
    • Gill, G.V.1
  • 41
    • 0034844734 scopus 로고    scopus 로고
    • Alternative routes of administration as an approach to improve insulin therapy: Update on dermal, oral, nasal and pulmonary insulin delivery
    • Heinemann L, Pfutzner A, Heise T. Alternative routes of administration as an approach to improve insulin therapy: Update on dermal, oral, nasal and pulmonary insulin delivery. Curr Pharm Des 2001;7:1327-51.
    • (2001) Curr Pharm Des , vol.7 , pp. 1327-1351
    • Heinemann, L.1    Pfutzner, A.2    Heise, T.3
  • 42
    • 0034934052 scopus 로고    scopus 로고
    • Overcoming skin's barrier: The search for effective and user-friendly drug delivery
    • Prausnitz MR. Overcoming skin's barrier: The search for effective and user-friendly drug delivery. Diabetes Technol Ther 2001;3:233-6.
    • (2001) Diabetes Technol Ther , vol.3 , pp. 233-236
    • Prausnitz, M.R.1
  • 43
    • 0032472394 scopus 로고    scopus 로고
    • Transdermal delivery of regular insulin to chronic diabetic rats: Effect of skin preparation and electrical enhancement
    • Zakzewski CA, Wasilewski J, Cawley P, Ford W. Transdermal delivery of regular insulin to chronic diabetic rats: Effect of skin preparation and electrical enhancement. J Control Release 1998;50:267-72.
    • (1998) J Control Release , vol.50 , pp. 267-272
    • Zakzewski, C.A.1    Wasilewski, J.2    Cawley, P.3    Ford, W.4
  • 44
    • 0037123744 scopus 로고    scopus 로고
    • Effect of sonication parameters on transdermal delivery of insulin to hairless rats
    • Boucaud A, Garrigue MA, Machet L, Vaillant L, Patat F. Effect of sonication parameters on transdermal delivery of insulin to hairless rats. J Control Release 2002;81:113-9.
    • (2002) J Control Release , vol.81 , pp. 113-119
    • Boucaud, A.1    Garrigue, M.A.2    Machet, L.3    Vaillant, L.4    Patat, F.5
  • 45
    • 18044402481 scopus 로고    scopus 로고
    • A combination of iontophoresis and the chelating agent 1, 10 phenanthroline act synergistically as penetration enhancers
    • Brand RM, Hannah TL, Hamel FG. A combination of iontophoresis and the chelating agent 1, 10 phenanthroline act synergistically as penetration enhances. AAPS Pharm Sci 2000;2:35.
    • (2000) AAPS Pharm Sci , vol.2 , pp. 35
    • Brand, R.M.1    Hannah, T.L.2    Hamel, F.G.3
  • 46
  • 47
    • 0032917368 scopus 로고    scopus 로고
    • Transdermal iontophoretic delivery of bovine insulin and monomeric human insulin analogue
    • Kanikkannan N, Singh J, Romarao P. Transdermal iontophoretic delivery of bovine insulin and monomeric human insulin analogue. J Control Release 1999;59:99-105.
    • (1999) J Control Release , vol.59 , pp. 99-105
    • Kanikkannan, N.1    Singh, J.2    Romarao, P.3
  • 48
    • 0032720359 scopus 로고    scopus 로고
    • The pretreatment effect of chemical skin penetration enhancers in transdermal drug delivery using iontophoresis
    • Choi EH, Lee SH, Ahn SK, Hwang SM. The pretreatment effect of chemical skin penetration enhancers in transdermal drug delivery using iontophoresis. Skin Pharmacol Appl Skin Physiol 1999;12:326-35.
    • (1999) Skin Pharmacol Appl Skin Physiol , vol.12 , pp. 326-335
    • Choi, E.H.1    Lee, S.H.2    Ahn, S.K.3    Hwang, S.M.4
  • 49
    • 0028851990 scopus 로고
    • Delivery of systemic regular insulin via the ocular route in cats
    • Morgan RV. Delivery of systemic regular insulin via the ocular route in cats. J Ocul Pharmacol Ther 1995;11:565-73.
    • (1995) J Ocul Pharmacol Ther , vol.11 , pp. 565-573
    • Morgan, R.V.1
  • 51
    • 0019779224 scopus 로고
    • The effectiveness of rectal administration of insulin suppository on normal and diabetic subjects
    • Yamasaki Y, Shichiri M, Kawamori R, Kikuchi M, Yagi T, Arai S, et al. The effectiveness of rectal administration of insulin suppository on normal and diabetic subjects. Diabetes Care 1981;4:454-8.
    • (1981) Diabetes Care , vol.4 , pp. 454-458
    • Yamasaki, Y.1    Shichiri, M.2    Kawamori, R.3    Kikuchi, M.4    Yagi, T.5    Arai, S.6
  • 52
    • 0035017734 scopus 로고    scopus 로고
    • Pancreas transplantation for treatment of diabetes mellitus
    • Sutherland DE, Gruessner RW, Gruessner AC. Pancreas transplantation for treatment of diabetes mellitus. World J Surg 2001;25:487-96.
    • (2001) World J Surg , vol.25 , pp. 487-496
    • Sutherland, D.E.1    Gruessner, R.W.2    Gruessner, A.C.3
  • 53
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-8.
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6
  • 54
    • 0034573840 scopus 로고    scopus 로고
    • Strategies for immunoisolation in islet transplantation: Challenges for the twenty-first century
    • Ohgawara H. Strategies for immunoisolation in islet transplantation: Challenges for the twenty-first century. J Hepatobiliary Pancreat Surg 2000;7:374-9.
    • (2000) J Hepatobiliary Pancreat Surg , vol.7 , pp. 374-379
    • Ohgawara, H.1
  • 55
    • 0034062841 scopus 로고    scopus 로고
    • Engineering challenges in the development of an encapsulated cell system for treatment of type 1 diabetes
    • Sambanis A. Engineering challenges in the development of an encapsulated cell system for treatment of type 1 diabetes. Diabetes Technol Ther 2000;2:81-9.
    • (2000) Diabetes Technol Ther , vol.2 , pp. 81-89
    • Sambanis, A.1
  • 56
    • 0035433196 scopus 로고    scopus 로고
    • Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane
    • Duvivier-Kali VF, Omer A, Parent RJ, O'Neill JJ, Weir GC. Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes 2001;50:1698-705.
    • (2001) Diabetes , vol.50 , pp. 1698-1705
    • Duvivier-Kali, V.F.1    Omer, A.2    Parent, R.J.3    O'Neill, J.J.4    Weir, G.C.5
  • 57
    • 0035814242 scopus 로고    scopus 로고
    • The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules
    • King A, Sandler S, Andersson A. The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules. J Biomed Mater Res. 2001;57:374-83.
    • (2001) J Biomed Mater Res , vol.57 , pp. 374-383
    • King, A.1    Sandler, S.2    Andersson, A.3
  • 59
    • 0035057914 scopus 로고    scopus 로고
    • From stem cells to beta cells: New strategies in cell therapy of diabetes mellitus
    • Soria B, Skoudy A, Martin F. From stem cells to beta cells: New strategies in cell therapy of diabetes mellitus. Diabetologia 2001;44:407-15.
    • (2001) Diabetologia , vol.44 , pp. 407-415
    • Soria, B.1    Skoudy, A.2    Martin, F.3
  • 60
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
    • Ramiya VK, Maraist M, Arfors KE, Schatz DA, Peck AB, Cornelius JG. Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 2000;6:278-82.
    • (2000) Nat Med , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 61
    • 0030741524 scopus 로고    scopus 로고
    • Scientific and political impediments to successful islet transplantation
    • Weir GC, Bonner-Weir S. Scientific and political impediments to successful islet transplantation. Diabetes 1997;46:1247-56.
    • (1997) Diabetes , vol.46 , pp. 1247-1256
    • Weir, G.C.1    Bonner-Weir, S.2
  • 62
    • 0034666757 scopus 로고    scopus 로고
    • Modification of inflammatory response to implanted biomedical materials in vivo by surface bound superoxide dismutase mimics
    • Udipi K, Ornberg RL, Thurmond KB II, Settle SL, Forster D, Riley D. Modification of inflammatory response to implanted biomedical materials in vivo by surface bound superoxide dismutase mimics. J Biomed Mater Res 2000;51:549-60.
    • (2000) J Biomed Mater Res , vol.51 , pp. 549-560
    • Udipi, K.1    Ornberg, R.L.2    Thurmond K.B. II3    Settle, S.L.4    Forster, D.5    Riley, D.6
  • 64
    • 0035185043 scopus 로고    scopus 로고
    • In vivo investigations on composites made of resorbable ceramics and poly(lactide) used as bone graft substitutes
    • Ingatius AA, Betz O, Augat P, Claes LE. In vivo investigations on composites made of resorbable ceramics and poly(lactide) used as bone graft substitutes. J Biomed Mater Res 2001;58:701-9.
    • (2001) J Biomed Mater Res , vol.58 , pp. 701-709
    • Ignatius, A.A.1    Betz, O.2    Augat, P.3    Claes, L.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.