Prolongation of LAS40 (duration of the low amplitude electric potential component (<40μV) of the terminal portion of the QRS) induced by isoproterenol in 11 patients with Brugada syndrome

Circulation Journal

Volumn 66, Issue 12, 2002, Pages 1101-1104

  Takagi, Akihiko ^a   Nakazawa, Kiyoshi ^a   Sakurai, Tsuneharu ^a   Nanke, Toshihiko ^a   Miyake, Fumihiko ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Brugada syndrome; Isoproterenol; Late potential; Signal averaged electrocardiography

Indexed keywords

ISOPRENALINE; DIAGNOSTIC AGENT; HYPOCHOLESTEROLEMIC AGENT;

ADULT; AMPLITUDE MODULATION; ARRHYTHMOGENESIS; ARTICLE; BRUGADA SYNDROME; CARDIOMYOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; HEART CONDUCTION; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART RIGHT VENTRICLE; HEART VENTRICLE FIBRILLATION; HUMAN; MALE; QRS COMPLEX; DRUG EFFECT; ELECTROCARDIOGRAPHY; HEART BUNDLE BRANCH BLOCK; HEART RATE; MIDDLE AGED; PATHOPHYSIOLOGY; REFERENCE VALUE;

ADULT; ANTICHOLESTEREMIC AGENTS; BUNDLE-BRANCH BLOCK; ELECTROCARDIOGRAPHY; HEART RATE; HUMANS; ISOPROTERENOL; MALE; MIDDLE AGED; REFERENCE VALUES;

EID: 0036895989     PISSN: 13469843     EISSN: None     Source Type: Journal    
DOI: 10.1253/circj.66.1101     Document Type: Article

References (16)

1. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol 1992; 20: 1391-1396.
2. Itoh H, Shimizu M, Ino H, Okeie K, Yamaguchi M, Fujino N, et al, Hokuriku Brugada Study Group. Arrhythmias in patients with Brugada-type electrocardiographic findings. Jpn Circ J 2001; 65: 483-486.
3. Shimada M, Miyazaki T, Miyoshi S, Soejima K, Hod S, Mitamura H, et al. Sustained monomorphic ventricular tachycardia in a patient with Brugada syndrome. Jpn Circ J 1996; 60: 364-370.
4. Viskin S, Belhassen B. Idiopathic ventricular fibrillation. Am Heart J 1990; 120: 661-671.
5. Antzelevitch C. Ion channels and ventricular arrhythmias: Cellular and ionic mechanisms underlying the Brugada syndrome. Curr Opin Cardiol 1999; 14: 274-279.
6. Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 1999; 100: 1660-1666.
7. Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada J, Brugada P, et al. Genetic basis and molecular mechanism for idiopathic ventricular fibrillation. Nature 1998; 392: 293-296.
8. Ikeda T, Sakurada H, Sakabe K, Sakata T, Takami M, Tezuka N, et al. Assessment of noninvasive markers in identifying patients at risk in the Brugada syndrome: Insight into risk stratification. J Am Coll Cardiol 2001; 37: 1628-1634.
9. Kasanuki H, Ohnishi S, Ohtuka M, Matsuda N, Nirei T, Isogai R. Idiopathic ventricular fibrillation induced with vagal activity in patients without obvious heart disease. Circulation 1997; 95: 2277-2285.
10. Corrado D, Basso C, Buja G, Nava A, Rossi L, Thiene G. Right bundle branch block, right precordial ST-segment elevation, and sudden death in young people. Circulation 2001; 103: 710-717.
11. Nakazawa K, Shiota K, Takagi A, Matsumoto N, Nanke T, Sakurai T, et al. Appearance of a conduction delay at the right ventricular outflow tract in patient with Brugada syndrome coexist with idiopathic ventricular tachycardia. St Marianna Med J 2000; 28: 129-136.
12. Goldberger JJ, Ahmed MW, Parker MA, Kadish AH. Assessment of effects of autonomic stimulation and blockade on the signal-averaged electrocardiogram. Circulation 1994; 89: 1656-1664.
13. Simson MB. Use of signals in the terminal QRS complex to identify patients with ventricular tachycardia after myocardial infarction. Circulation 1981; 64: 235-242.
14. Greenspon AJ, Volosin K. The effects of atrial pacing on the signal-averaged electrocardiogram in patients with coronary artery disease. Am Heart J 1990; 119: 29-34.
15. Caref EB, Goldberg N, Mendelson L, Hanley G, Okereke R, Stein RA, et al. Effects of exercise on the signal-averaged electrocardiogram in coronary artery disease. Am J Cardiol 1990; 66: 54-58.
16. Fujimori H, Katoh T, Kim EM, Kamei S, Kuroki S, Hayakawa H. The influence of heart rate change on high frequency components of signal-averaged QRS complex. Heart 1993; 25: 76-81.