Association of chromosome 10 losses and negative prognosis in oligoastrocytomas

Annals of Neurology

Volumn 52, Issue 6, 2002, Pages 842-845

  Bissola, Lorena ^a   Eoli, Marica ^b   Pollo, Bianca ^b   Merciai, Bianca Maria ^a   Silvani, Antonio ^b   Salsano, Ettore ^a   Maccagnano, Carmelo ^a   Bruzzone, Maria Grazia ^a   Fuhrman Conti, Anna Maria ^a   Solero, Carlo Lazzaro ^c   Giombini, Sergio ^c   Broggi, Giovanni ^c   Boiardi, Amerigo ^b   Finocchiaro, Gaetano ^a,d  

^a UNIVERSITY OF MILAN   (Italy)

^b Neurological Clinic   (Italy)

^c NONE   (Italy)

^d Ist Naz Stud e la Cura dei Tumori   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARMUSTINE; CISPLATIN; LOMUSTINE; PROCARBAZINE; VINCRISTINE;

ADULT; AGED; ARTICLE; ASTROCYTOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CHROMOSOME 10; CHROMOSOME 10Q; CHROMOSOME 17P; CHROMOSOME 19Q; CHROMOSOME 1P; CHROMOSOME LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GLIOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE MARKER; MUTATION; PRIORITY JOURNAL; PROGNOSIS;

ADULT; AGED; ASTROCYTOMA; CHI-SQUARE DISTRIBUTION; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 10; CONFIDENCE INTERVALS; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SURVIVAL RATE;

EID: 0036895444     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10405     Document Type: Article

References (17)

1. Fults D, Brockmeyer D, Tullous MW, et al. p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression. Cancer Res 1992;52:674-679.
2. von Deimling A, Louis DN, von Ammon K, et al. Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas. Cancer Res 1992;52:4277-4279.
3. Kraus JA, Koopmann J, Kaskel P, et al. Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligo-dendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 1995;54:91-95.
4. Reifenberger J, Reifenberger G, Liu L, et al. Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. Am J Pathol 1994;145:1175-1190.
5. Maintz D, Fiedler K, Koopmann J, et al. Molecular genetic evidence for subtypes of oligoastrocytomas. J Neuropathol Exp Neurol 1997;56:1098-1104.
6. Rasheed BK, Wiltshire RN, Bigner SH, Bigner DD. Molecular pathogenesis of malignant gliomas. Curr Opin Oncol 1999;11:162-167.
7. Kim L, Hochberg FH, Thornton AF, et al. Procarbazine, lomustine, and vincristine (PCV) chemotherapy for grade III and grade IV oligoastrocytomas. J Neurosurg 1996;85:602-607.
8. Smith JS, Perry A, Borell TJ, et al. Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J Clin Oncol 2000;18:636-645.
9. Cairncross JG, Ueki K, Zlatescu MC, et al. Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 1998;90:1473-1479.
10. Sasaki H, Zlatescu MC, Betensky RA, et al. PTEN is a target of chromosome 10q loss in anaplastic oligodendrogliomas and PTEN alterations are associated with poor prognosis. Am J Pathol 2001;159:359-367.
11. Reifenberger G, Kros JM, Burger PC, et al. Tumours of the Nervous System (Oligodendroglial Tumours and Mixed Gliomas). Lyon: IARC Press, 2000:55-70.
12. Albarosa R, Colombo BM, Roz L, et al. Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q. Am J Hum Genet 1996;58:1260-1267.
13. Macdonald DR, Cascino TL, Schold SC, Cairncross JG. Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 1990;8:1277-1280.
14. Zlatescu MC, TehraniYazdi A, Sasaki H, et al. Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Res 2001;61:6713-6715.
15. Mueller W, Hartmann C, Hoffmann A, et al. Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets. Am J Pathol 2002;161:313-319.
16. Scerrati M, Roselli R, Iacoangeli M, et al. Prognostic factors in low grade (WHO grade II) gliomas of the cerebral hemispheres: The role of surgery. J Neurol Neurosurg Psychiatry 1996;61:291-296.
17. Vives KP, Piepmeier JM. Complications and expected outcome of glioma surgery. J Neurooncol 1999;42:289-302.