Suppression of cytochrome P450 2C11 by aromatic hydrocarbons: Mechanistic insights from studies of the 5′-flanking region of the CYP2C11 gene

Drug Metabolism and Disposition

Volumn 30, Issue 12, 2002, Pages 1385-1392

  Bhathena, Anahita ^a   Lee, Chunja ^a   Riddick, David S ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 2C11; CYTOKINE; DIOXIN; INTERLEUKIN 1BETA; MESSENGER RNA; TRANSCRIPTION FACTOR; CYP2C11 PROTEIN, RAT; ENZYME INHIBITOR; STEROID 16ALPHA MONOOXYGENASE; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DNA VECTOR; ENZYME INDUCTION; ENZYME REPRESSION; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; RAT; RECEPTOR BINDING; REPORTER GENE; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; FISCHER 344 RAT; GENETICS; MALE; METABOLISM; PHYSIOLOGY;

ANIMALIA;

5' FLANKING REGION; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; ENZYME INDUCTION; ENZYME INHIBITORS; ENZYME REPRESSION; HUMANS; HYDROCARBONS, AROMATIC; MALE; MICE; RATS; RATS, INBRED F344; STEROID 16-ALPHA-HYDROXYLASE; TUMOR CELLS, CULTURED;

EID: 0036892570     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.12.1385     Document Type: Article

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