An expedient synthesis of Nα-protected-L-tetrahydrofuranylglycine and its application in the synthesis of novel substrate based inhibitors of HIV-1 protease

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 24, 2002, Pages 3615-3617

  Rajesh, S ^a   Ami, Ei'ichi ^a   Kotake, Tomoya ^a   Kimura, Tooru ^a   Hayashi, Yoshio ^a   Kiso, Yoshiaki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

9 FLUORENYLMETHYLOXYCARBONYL TETRAHYDROFURANYLGLYCINE; GLYCINE DERIVATIVE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VINYL DERIVATIVE; VIRUS ENZYME; FURAN DERIVATIVE; GLYCINE; OLIGOPEPTIDE; PROTEINASE;

ARTICLE; CYCLOADDITION; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR INTERACTION; CHEMISTRY; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

FURANS; GLYCINE; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036889983     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00781-3     Document Type: Article

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