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Volumn 84, Issue 3, 2002, Pages 219-228

Metabolism and distribution of phenanthridine trypanocides in Trypanosoma brucei

Author keywords

African trypanosomiasis; Kinetoplast; Metabolism; Phenanthridine trypanocides; Trypanosoma brucei

Indexed keywords

ETHIDIUM BROMIDE; ISOMETAMIDIUM CHLORIDE; PHENANTHRIDINE DERIVATIVE;

EID: 0036889703     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-706X(02)00188-2     Document Type: Article
Times cited : (27)

References (28)
  • 1
    • 0029624344 scopus 로고
    • Kinetoplasts play an important role in the drug responses of Trypanosoma brucei
    • Agbe A., Yielding K.L. Kinetoplasts play an important role in the drug responses of Trypanosoma brucei. J. Parasitol. 81:1995;968-973.
    • (1995) J. Parasitol. , vol.81 , pp. 968-973
    • Agbe, A.1    Yielding, K.L.2
  • 2
    • 0017186837 scopus 로고
    • Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: Effects of phenobarbital
    • Agosin M., Naquira C., Paulin J., Capdevila J. Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital. Science. 194:1976;195-197.
    • (1976) Science , vol.194 , pp. 195-197
    • Agosin, M.1    Naquira, C.2    Paulin, J.3    Capdevila, J.4
  • 3
    • 0017145627 scopus 로고
    • Hemoproteins in Trypanosoma cruzi with emphasis on microsomal pigments
    • Agosin M., Naquira C., Capdevila J., Paulin J. Hemoproteins in Trypanosoma cruzi with emphasis on microsomal pigments. Int. J. Biochem. 7:1976;585-593.
    • (1976) Int. J. Biochem. , vol.7 , pp. 585-593
    • Agosin, M.1    Naquira, C.2    Capdevila, J.3    Paulin, J.4
  • 6
    • 0022592803 scopus 로고
    • Characteristics of Ethidium uptake by the trypanosomatid flagellates Crithidia fasciculata and Leptomonas seymouri
    • Coolbear K.P., Midgley M. Characteristics of Ethidium uptake by the trypanosomatid flagellates Crithidia fasciculata and Leptomonas seymouri. Antimicrob. Agents Chemother. 29:1986;258-262.
    • (1986) Antimicrob. Agents Chemother. , vol.29 , pp. 258-262
    • Coolbear, K.P.1    Midgley, M.2
  • 7
    • 0030465180 scopus 로고    scopus 로고
    • Pharmacokinetics of the chemoprophylactic and chemotherapeutic trypanocidal drug Isometamidium chloride (Samorin) in cattle
    • Eisler M.C. Pharmacokinetics of the chemoprophylactic and chemotherapeutic trypanocidal drug Isometamidium chloride (Samorin) in cattle. Am. Soc. Pharmacol. Exp. Therap. 24:1996;1355-1361.
    • (1996) Am. Soc. Pharmacol. Exp. Therap. , vol.24 , pp. 1355-1361
    • Eisler, M.C.1
  • 8
  • 9
    • 0035192596 scopus 로고    scopus 로고
    • The programme against African Trypanosomiasis: Aims, objectives and achievements
    • Hursey B.S. The programme against African Trypanosomiasis: aims, objectives and achievements. Trends Parasitol. 17:2001;2-3.
    • (2001) Trends Parasitol. , vol.17 , pp. 2-3
    • Hursey, B.S.1
  • 10
    • 0030769022 scopus 로고    scopus 로고
    • Susceptibility of dyskinetoplastic Trypanosoma evansi and T. equiperdum to isometamidium chloride
    • Kaminsky R., Schmid C., Lan Z.R. Susceptibility of dyskinetoplastic Trypanosoma evansi and T. equiperdum to isometamidium chloride. Parasitol. Res. 83:1997;816-818.
    • (1997) Parasitol. Res. , vol.83 , pp. 816-818
    • Kaminsky, R.1    Schmid, C.2    Lan, Z.R.3
  • 11
    • 0023854524 scopus 로고
    • Pharmacokinetic and hispathological investigations of isometamidium in cattle
    • Kinabo L.D.B., Bogan J.A. Pharmacokinetic and hispathological investigations of isometamidium in cattle. Res. Vet. Sci. 44:1988;267-269.
    • (1988) Res. Vet. Sci. , vol.44 , pp. 267-269
    • Kinabo, L.D.B.1    Bogan, J.A.2
  • 12
    • 0014884946 scopus 로고
    • Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose
    • Lanham S.M., Godfrey D.G. Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose. Exp. Parasitol. 28:1970;521-534.
    • (1970) Exp. Parasitol. , vol.28 , pp. 521-534
    • Lanham, S.M.1    Godfrey, D.G.2
  • 13
    • 0030220510 scopus 로고    scopus 로고
    • 14C isometamidium in non-infected and Trypanosoma congolense infected Boran cattle
    • 14C isometamidium in non-infected and Trypanosoma congolense infected Boran cattle. Acta Trop. 61:1996;277-292.
    • (1996) Acta Trop. , vol.61 , pp. 277-292
    • Murilla, G.A.1    Mdachi, R.E.2    Karanja, W.M.3
  • 16
    • 0025021003 scopus 로고
    • Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs
    • Shapiro T.A., Englund P.T. Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs. Proc. Natl. Acad. Sci. USA. 87:1990;950-954.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 950-954
    • Shapiro, T.A.1    Englund, P.T.2
  • 18
    • 0026648157 scopus 로고
    • Transport of isometamidium (Samorin) by drug-resistant and drug-sensitive Trypanosoma congolense
    • Sutherland I.A., Mounsey A., Holmes P.H. Transport of isometamidium (Samorin) by drug-resistant and drug-sensitive Trypanosoma congolense. Parasitology. 104:1992;461-467.
    • (1992) Parasitology , vol.104 , pp. 461-467
    • Sutherland, I.A.1    Mounsey, A.2    Holmes, P.H.3
  • 19
    • 0026625130 scopus 로고
    • Kinetic modelling of isometamidium chloride (Samorin) uptake by Trypanosoma congolense
    • Sutherland I.A., Mounsey A., Eisler M., Holmes P.H. Kinetic modelling of isometamidium chloride (Samorin) uptake by Trypanosoma congolense. Parasitology. 105:1992;91-95.
    • (1992) Parasitology , vol.105 , pp. 91-95
    • Sutherland, I.A.1    Mounsey, A.2    Eisler, M.3    Holmes, P.H.4
  • 20
    • 0032145046 scopus 로고    scopus 로고
    • HPTLC and HPLC determination of isometamidium in the presence of its manufacturing and degradation impurities
    • Tettey J.N.A., Skellern G.G., Midgley J.M., Grant M.H. HPTLC and HPLC determination of isometamidium in the presence of its manufacturing and degradation impurities. J. Pharm. Biomed. Anal. 17:1998;713-718.
    • (1998) J. Pharm. Biomed. Anal. , vol.17 , pp. 713-718
    • Tettey, J.N.A.1    Skellern, G.G.2    Midgley, J.M.3    Grant, M.H.4
  • 21
    • 0032939943 scopus 로고    scopus 로고
    • Intracellular localisation and metabolism of the phenanthridinium trypanocide, ethidium bromide, by isolated rat hepatocytes
    • Tettey J.N.A., Skellern G.G., Midgley J.M., Grant M.H., Wilkinson R., Pitt A.R. Intracellular localisation and metabolism of the phenanthridinium trypanocide, ethidium bromide, by isolated rat hepatocytes. Xenobiotica. 29:1999;349-360.
    • (1999) Xenobiotica , vol.29 , pp. 349-360
    • Tettey, J.N.A.1    Skellern, G.G.2    Midgley, J.M.3    Grant, M.H.4    Wilkinson, R.5    Pitt, A.R.6
  • 22
    • 0032705574 scopus 로고    scopus 로고
    • The effect of inducing agents on the metabolism of ethidium bromide by isolated rat hepatocytes
    • Tettey J.N.A., Skellern G.G., Midgley J.M., Grant M.H., Pitt A.R. The effect of inducing agents on the metabolism of ethidium bromide by isolated rat hepatocytes. Chem. Biol. Interact. 123:1999;105-115.
    • (1999) Chem. Biol. Interact. , vol.123 , pp. 105-115
    • Tettey, J.N.A.1    Skellern, G.G.2    Midgley, J.M.3    Grant, M.H.4    Pitt, A.R.5
  • 23
    • 0032824334 scopus 로고    scopus 로고
    • Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium®
    • Tettey J.N.A., Skellern G.G., Grant M.H., Midgley J.M. Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium® J. Pharm. Biomed. Anal. 18:1999;1-7.
    • (1999) J. Pharm. Biomed. Anal. , vol.18 , pp. 1-7
    • Tettey, J.N.A.1    Skellern, G.G.2    Grant, M.H.3    Midgley, J.M.4
  • 24
    • 0011496939 scopus 로고
    • Physical studies on the interaction of lysergic acid diethylamide and trypanocidal dyes with DNA and DNA-containing genetic material
    • Wagner T.E. Physical studies on the interaction of lysergic acid diethylamide and trypanocidal dyes with DNA and DNA-containing genetic material. Prog. Mol. Subcell. Biol. 2:1971;152-162.
    • (1971) Prog. Mol. Subcell. Biol. , vol.2 , pp. 152-162
    • Wagner, T.E.1
  • 25
    • 0028949538 scopus 로고
    • Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis
    • Wang C.C. Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis. Ann. Rev. Pharmacol. Toxicol. 35:1995;93-127.
    • (1995) Ann. Rev. Pharmacol. Toxicol. , vol.35 , pp. 93-127
    • Wang, C.C.1
  • 26
    • 0028892399 scopus 로고
    • The accumulation and compartmentalization of isometamidium chloride in Trypanosoma congolense, monitored by its intrinsic fluorescence
    • Wilkes J.M., Peregrine A.S., Zilberstein D. The accumulation and compartmentalization of isometamidium chloride in Trypanosoma congolense, monitored by its intrinsic fluorescence. Biochem. J. 312:1995;319-329.
    • (1995) Biochem. J. , vol.312 , pp. 319-329
    • Wilkes, J.M.1    Peregrine, A.S.2    Zilberstein, D.3
  • 27
    • 0030881430 scopus 로고    scopus 로고
    • Modulation of mitochondrial electrical potential: A candidate mechanism for drug resistance in African trypanosomes
    • Wilkes J.M., Mulugeta W., Wells C., Peregrine A.S. Modulation of mitochondrial electrical potential: a candidate mechanism for drug resistance in African trypanosomes. Biochem. J. 325:1997;755-761.
    • (1997) Biochem. J. , vol.325 , pp. 755-761
    • Wilkes, J.M.1    Mulugeta, W.2    Wells, C.3    Peregrine, A.S.4
  • 28
    • 0027256424 scopus 로고
    • Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense
    • Zilberstein D., Wilkes J., Hirumi H., Peregrine A.S. Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense. Biochem. J. 292:1993;31-35.
    • (1993) Biochem. J. , vol.292 , pp. 31-35
    • Zilberstein, D.1    Wilkes, J.2    Hirumi, H.3    Peregrine, A.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.