메뉴 건너뛰기




Volumn 108, Issue 2-3, 2002, Pages 161-168

Aprotinin counteracts heparin-induced inhibition of platelet contractile force

Author keywords

Aprotinin; Cardiopulmonary bypass; Clot retraction; Heparin; Platelet contractile force; Platelet dysfunction

Indexed keywords

APROTININ; ATROXIN; BATROXOBIN; CALCIUM CHLORIDE; HEPARIN;

EID: 0036878199     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(02)00403-6     Document Type: Article
Times cited : (11)

References (48)
  • 1
    • 0025227931 scopus 로고
    • Bleeding complications associated with cardiopulmonary bypass
    • Woodman R.C., Harker L.A. Bleeding complications associated with cardiopulmonary bypass. Blood. 76:1990;1680-1697.
    • (1990) Blood , vol.76 , pp. 1680-1697
    • Woodman, R.C.1    Harker, L.A.2
  • 2
    • 0019180607 scopus 로고
    • Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: Acquired transient platelet dysfunction associated with selective α-granule release
    • Harker L.A., Malpass T.W., Branson H.E., Hessel E.A. II, Slichter S.J. Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: acquired transient platelet dysfunction associated with selective α-granule release. Blood. 56:1980;824-834.
    • (1980) Blood , vol.56 , pp. 824-834
    • Harker, L.A.1    Malpass, T.W.2    Branson, H.E.3    Hessel E.A. II4    Slichter, S.J.5
  • 6
    • 0027243485 scopus 로고
    • Reduction of heparin binding to and inhibition of platelets by aprotinin
    • John L.C., Rees G.M., Kovacs I.B. Reduction of heparin binding to and inhibition of platelets by aprotinin. Ann. Thorac. Surg. 55:1993;1175-1179.
    • (1993) Ann. Thorac. Surg. , vol.55 , pp. 1175-1179
    • John, L.C.1    Rees, G.M.2    Kovacs, I.B.3
  • 8
    • 0025855879 scopus 로고
    • Heparin inhibition of von Willebrand Factor-dependent platelet function in vitro and in vivo
    • Sobel M., McNeill P.M., Carlson P.L., Kermode J.C., Adelman B., Conroy R.et al. Heparin inhibition of von Willebrand Factor-dependent platelet function in vitro and in vivo. J. Clin. Invest. 87:1991;1787-1793.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1787-1793
    • Sobel, M.1    McNeill, P.M.2    Carlson, P.L.3    Kermode, J.C.4    Adelman, B.5    Conroy, R.6
  • 9
    • 0028912314 scopus 로고
    • Reductions in platelet force development by cardiopulmonary bypass are associated with hemorrhage
    • Greilich P.E., Carr M.E., Carr S.L., Chang A.S. Reductions in platelet force development by cardiopulmonary bypass are associated with hemorrhage. Anesth. Analg. 80:1995;459-465.
    • (1995) Anesth. Analg. , vol.80 , pp. 459-465
    • Greilich, P.E.1    Carr, M.E.2    Carr, S.L.3    Chang, A.S.4
  • 10
    • 0025686150 scopus 로고
    • Influence of high-dose aprotinin treatment on blood loss and coagulation patterns in patients undergoing myocardial revascularization
    • Dietrich W., Spannagl M., Jochum M., Wendt P., Schramm W., Barankay A.et al. Influence of high-dose aprotinin treatment on blood loss and coagulation patterns in patients undergoing myocardial revascularization. Anesthesiology. 73:1990;1119-1126.
    • (1990) Anesthesiology , vol.73 , pp. 1119-1126
    • Dietrich, W.1    Spannagl, M.2    Jochum, M.3    Wendt, P.4    Schramm, W.5    Barankay, A.6
  • 11
  • 12
    • 0026607394 scopus 로고
    • Platelet protection by aprotinin in cardiopulmonary bypass: Electron microscopic study
    • Lavee J., Savion N., Smolinsky A., Goor D.A., Mohr R. Platelet protection by aprotinin in cardiopulmonary bypass: electron microscopic study. Ann. Thorac. Surg. 53:1992;477-481.
    • (1992) Ann. Thorac. Surg. , vol.53 , pp. 477-481
    • Lavee, J.1    Savion, N.2    Smolinsky, A.3    Goor, D.A.4    Mohr, R.5
  • 13
    • 0026493593 scopus 로고
    • Aprotinin prevents cardiopulmonary bypass-induced platelet dysfunction. A scanning electron microscopic study
    • Mohr R., Goor D.A., Lusky A., Lavee J. Aprotinin prevents cardiopulmonary bypass-induced platelet dysfunction. A scanning electron microscopic study. Circulation. 86:1992;II405-II409.
    • (1992) Circulation , vol.86
    • Mohr, R.1    Goor, D.A.2    Lusky, A.3    Lavee, J.4
  • 14
    • 0025875932 scopus 로고
    • Measurement of platelet-mediated force development during plasma clot formation
    • Carr M.E., Zekert S.L. Measurement of platelet-mediated force development during plasma clot formation. Am. J. Med. Sci. 302:1991;13-18.
    • (1991) Am. J. Med. Sci. , vol.302 , pp. 13-18
    • Carr, M.E.1    Zekert, S.L.2
  • 15
    • 0028953090 scopus 로고
    • Fibrin structure and concentration alter clot elastic modulus but do not alter platelet mediated force development
    • Carr M.E., Carr S.L. Fibrin structure and concentration alter clot elastic modulus but do not alter platelet mediated force development. Blood Coagul. Fibrinolysis. 6:1995;79-86.
    • (1995) Blood Coagul. Fibrinolysis , vol.6 , pp. 79-86
    • Carr, M.E.1    Carr, S.L.2
  • 16
    • 0028964837 scopus 로고
    • Glycoprotein IIb/IIIa blockade inhibits platelet mediated force development and reduces gel elastic modulus
    • Carr M.E., Carr S.L., Hantgan R.R., Braaten J. Glycoprotein IIb/IIIa blockade inhibits platelet mediated force development and reduces gel elastic modulus. Thromb. Haemost. 73:1995;499-505.
    • (1995) Thromb. Haemost. , vol.73 , pp. 499-505
    • Carr, M.E.1    Carr, S.L.2    Hantgan, R.R.3    Braaten, J.4
  • 17
    • 0031016637 scopus 로고    scopus 로고
    • A modified thromboelastographic method for monitoring c7E3 Fab in heparinized patients
    • Greilich P.E., Alving B.M., O'Neill K.L., Chang A.S., Reid T.J. A modified thromboelastographic method for monitoring c7E3 Fab in heparinized patients. Anesth. Analg. 84:1997;31-38.
    • (1997) Anesth. Analg. , vol.84 , pp. 31-38
    • Greilich, P.E.1    Alving, B.M.2    O'Neill, K.L.3    Chang, A.S.4    Reid, T.J.5
  • 18
  • 19
    • 85031211645 scopus 로고    scopus 로고
    • Development of platelet contractile force as a research and clinical measure of platelet function
    • in press
    • Carr ME. Development of platelet contractile force as a research and clinical measure of platelet function. Cell Biochem. Biophys. [in press].
    • Cell Biochem. Biophys.
    • Carr, M.E.1
  • 20
    • 0026147775 scopus 로고
    • Force monitoring of clot retraction during DDAVP therapy for the qualitative platelet disorder of uraemia: Report of a case
    • Carr M.E., Zekert S.L. Force monitoring of clot retraction during DDAVP therapy for the qualitative platelet disorder of uraemia: report of a case. Blood Coagul. Fibrinolysis. 2:1991;303-308.
    • (1991) Blood Coagul. Fibrinolysis , vol.2 , pp. 303-308
    • Carr, M.E.1    Zekert, S.L.2
  • 21
    • 0036860708 scopus 로고    scopus 로고
    • Enhanced platelet force development despite drug induced inhibition of platelet aggregation in patients with thromboangiitis obliterans
    • Carr M.E., Hackney M.H., Hines S.J., Heddinger S.P., Carr S.L., Martin E.J. Enhanced platelet force development despite drug induced inhibition of platelet aggregation in patients with thromboangiitis obliterans. Vasc. Endovasc. Surg. 36:2002;473-480.
    • (2002) Vasc. Endovasc. Surg. , vol.36 , pp. 473-480
    • Carr, M.E.1    Hackney, M.H.2    Hines, S.J.3    Heddinger, S.P.4    Carr, S.L.5    Martin, E.J.6
  • 22
    • 85031234524 scopus 로고    scopus 로고
    • Batroxobin-induced clots exhibit delayed and reduced platelet contractile force in some patients with clotting factor deficiencies
    • in press
    • Carr M.E., Carr S.L., Tildon T., Fisher L.M., Martin E.J. Batroxobin-induced clots exhibit delayed and reduced platelet contractile force in some patients with clotting factor deficiencies. J. Thromb. Haemost. [in press].
    • J. Thromb. Haemost.
    • Carr, M.E.1    Carr, S.L.2    Tildon, T.3    Fisher, L.M.4    Martin, E.J.5
  • 23
    • 0028037790 scopus 로고
    • At high heparin concentrations, protamine concentrations which reverse heparin anticoagulant effects are insufficient to reverse heparin anti-platelet effects
    • Carr M.E., Carr S.L. At high heparin concentrations, protamine concentrations which reverse heparin anticoagulant effects are insufficient to reverse heparin anti-platelet effects. Thromb. Res. 75:1994;617-630.
    • (1994) Thromb. Res. , vol.75 , pp. 617-630
    • Carr, M.E.1    Carr, S.L.2
  • 24
    • 0029993695 scopus 로고    scopus 로고
    • Heparin ablates force development during platelet mediated clot retraction
    • Carr M.E., Carr S.L., Greilich P.E. Heparin ablates force development during platelet mediated clot retraction. Thromb. Haemost. 75:1996;674-678.
    • (1996) Thromb. Haemost. , vol.75 , pp. 674-678
    • Carr, M.E.1    Carr, S.L.2    Greilich, P.E.3
  • 25
    • 0036526475 scopus 로고    scopus 로고
    • Delayed, reduced and inhibited thrombin production reduces platelet contractile force and results in weaker clot formation
    • Carr M.E., Martin E.J., Carr S.L. Delayed, reduced and inhibited thrombin production reduces platelet contractile force and results in weaker clot formation. Blood Coagul. Fibrinolysis. 13:2002;193-197.
    • (2002) Blood Coagul. Fibrinolysis , vol.13 , pp. 193-197
    • Carr, M.E.1    Martin, E.J.2    Carr, S.L.3
  • 26
    • 0013110906 scopus 로고
    • Effect of non-heparin thrombin antagonists on platelet force development during dot retraction
    • Carr M.E., Zekert S.L. Effect of non-heparin thrombin antagonists on platelet force development during dot retraction. Cell Biochem. Biophys. 69:1993;1241.
    • (1993) Cell Biochem. Biophys. , vol.69 , pp. 1241
    • Carr, M.E.1    Zekert, S.L.2
  • 27
    • 0027931362 scopus 로고
    • Quantitative assessment of platelet function and clot structure in patients with severe coronary artery disease
    • Greilich P.E., Carr M.E., Zekert S.L., Dent R.M. Quantitative assessment of platelet function and clot structure in patients with severe coronary artery disease. Am. J. Med. Sci. 307:1994;15-20.
    • (1994) Am. J. Med. Sci. , vol.307 , pp. 15-20
    • Greilich, P.E.1    Carr, M.E.2    Zekert, S.L.3    Dent, R.M.4
  • 28
    • 0035093810 scopus 로고    scopus 로고
    • Diabetes mellitus: A hypercoagulable state
    • Carr M.E. Diabetes mellitus: a hypercoagulable state. J. Diabetes Complications. 15:2001;44-54.
    • (2001) J. Diabetes Complications , vol.15 , pp. 44-54
    • Carr, M.E.1
  • 29
    • 0036400608 scopus 로고    scopus 로고
    • Elevated platelet contractile force (PCF) and clot elastic modulus (CEM) in diabetic patients: A potential marker of increased thrombotic risk
    • Carr M.E., Krishnaswami A., Martin E.J. Elevated platelet contractile force (PCF) and clot elastic modulus (CEM) in diabetic patients: a potential marker of increased thrombotic risk. Diabet. Med. 19:2002;862-866.
    • (2002) Diabet. Med. , vol.19 , pp. 862-866
    • Carr, M.E.1    Krishnaswami, A.2    Martin, E.J.3
  • 30
    • 0036847477 scopus 로고    scopus 로고
    • Patients with coronary artery disease who present with chest pain have significantly elevated platelet contractile force and clot elastic modulus
    • Krishnaswami A., Carr M.E., Jessie R.L., Kontos M., Minisi A.J., Ornato J.P.et al. Patients with coronary artery disease who present with chest pain have significantly elevated platelet contractile force and clot elastic modulus. Thromb Haemost. 88:2002;739-744.
    • (2002) Thromb Haemost , vol.88 , pp. 739-744
    • Krishnaswami, A.1    Carr, M.E.2    Jessie, R.L.3    Kontos, M.4    Minisi, A.J.5    Ornato, J.P.6
  • 31
    • 33745551242 scopus 로고
    • A rapid physiological coagulation method for determination of fibrinogen
    • Clauss A. A rapid physiological coagulation method for determination of fibrinogen. Acta Haematol. 17:1957;237-246.
    • (1957) Acta Haematol. , vol.17 , pp. 237-246
    • Clauss, A.1
  • 32
    • 0028156672 scopus 로고
    • Abnormal clot retraction, altered fibrin structure and normal platelet function in multiple myeloma
    • Carr M.E., Zekert S.L. Abnormal clot retraction, altered fibrin structure and normal platelet function in multiple myeloma. Am. J. Physiol. 266:1994;H1195-H1201.
    • (1994) Am. J. Physiol. , vol.266
    • Carr, M.E.1    Zekert, S.L.2
  • 33
    • 0019199058 scopus 로고
    • The effect of dextran 70 on the structure of plasma-derived fibrin gels
    • Carr M.E., Gabriel D.A. The effect of dextran 70 on the structure of plasma-derived fibrin gels. J. Lab. Clin. Med. 96:1980;985-993.
    • (1980) J. Lab. Clin. Med. , vol.96 , pp. 985-993
    • Carr, M.E.1    Gabriel, D.A.2
  • 34
    • 0029100827 scopus 로고
    • Effect of fibrin structure on plasmin-mediated dissolution of plasma clots
    • Carr M.E., Alving B.M. Effect of fibrin structure on plasmin-mediated dissolution of plasma clots. Blood Coagul. Fibrinolysis. 6:1995;567-573.
    • (1995) Blood Coagul. Fibrinolysis , vol.6 , pp. 567-573
    • Carr, M.E.1    Alving, B.M.2
  • 36
    • 0024313170 scopus 로고
    • Heparin binding to resting and activated platelets
    • Horne M.K., Chao S.C. Heparin binding to resting and activated platelets. Blood. 74:1989;238-243.
    • (1989) Blood , vol.74 , pp. 238-243
    • Horne, M.K.1    Chao, S.C.2
  • 37
    • 85031230015 scopus 로고
    • Protamine sulfate alters fibrin assembly and structure resulting in enhanced fibrinolysis
    • Carr M.E., Dent R.M. Protamine sulfate alters fibrin assembly and structure resulting in enhanced fibrinolysis. Clin. Res. 40:1992;420A.
    • (1992) Clin. Res. , vol.40
    • Carr, M.E.1    Dent, R.M.2
  • 38
    • 0027161452 scopus 로고
    • Inhibition of platelet function by heparin, an etiologic factor in postbypass hemorrhage
    • John L.C.H., Rees G.M., Kovacs I.B. Inhibition of platelet function by heparin, an etiologic factor in postbypass hemorrhage. J. Thorac. Cardiovasc. Surg. 105:1993;816-822.
    • (1993) J. Thorac. Cardiovasc. Surg. , vol.105 , pp. 816-822
    • John, L.C.H.1    Rees, G.M.2    Kovacs, I.B.3
  • 39
    • 0034108971 scopus 로고    scopus 로고
    • Platelet function during cardiopulmonary bypass not changed by two different doses of aprotinin
    • Santamaria A., Mateo J., Muniz-Diaz E., Oliver A., Murillo J., Litvan H.et al. Platelet function during cardiopulmonary bypass not changed by two different doses of aprotinin. Haematologica. 85:2000;381-385.
    • (2000) Haematologica , vol.85 , pp. 381-385
    • Santamaria, A.1    Mateo, J.2    Muniz-Diaz, E.3    Oliver, A.4    Murillo, J.5    Litvan, H.6
  • 41
    • 0030791587 scopus 로고    scopus 로고
    • Aprotinin inhibits plasmin-induced platelet activation during cardiopulmonary bypass
    • Shigeta O., Kojima H., Jikuya T., Terada Y., Atsumi N., Sakakibara Y.et al. Aprotinin inhibits plasmin-induced platelet activation during cardiopulmonary bypass. Circulation. 96:1997;569-574.
    • (1997) Circulation , vol.96 , pp. 569-574
    • Shigeta, O.1    Kojima, H.2    Jikuya, T.3    Terada, Y.4    Atsumi, N.5    Sakakibara, Y.6
  • 44
    • 0029897459 scopus 로고    scopus 로고
    • Aprotinin has no effect on platelet activation and adhesion during cardiopulmonary bypass
    • Wahba A., Black G., Koksch M., Rothe G., Preuner J., Schmitz G.et al. Aprotinin has no effect on platelet activation and adhesion during cardiopulmonary bypass. Thromb. Haemost. 75:1996;844-848.
    • (1996) Thromb. Haemost. , vol.75 , pp. 844-848
    • Wahba, A.1    Black, G.2    Koksch, M.3    Rothe, G.4    Preuner, J.5    Schmitz, G.6
  • 45
    • 0030119333 scopus 로고    scopus 로고
    • Aprotinin modulation of platelet activation in patients undergoing cardiopulmonary bypass operations
    • Primack C., Walenga J.M., Koza M.J., Shankey T.V., Pifarre R. Aprotinin modulation of platelet activation in patients undergoing cardiopulmonary bypass operations. Ann. Thorac. Surg. 61:1996;1188-1193.
    • (1996) Ann. Thorac. Surg. , vol.61 , pp. 1188-1193
    • Primack, C.1    Walenga, J.M.2    Koza, M.J.3    Shankey, T.V.4    Pifarre, R.5
  • 47
    • 0035171791 scopus 로고    scopus 로고
    • New antiinflammatory and platelet-preserving effects of aprotinin
    • Landis R.C., Haskard D.O., Taylor K.M. New antiinflammatory and platelet-preserving effects of aprotinin. Ann. Thorac. Surg. 72:2001;S1808-S1813.
    • (2001) Ann. Thorac. Surg. , vol.72
    • Landis, R.C.1    Haskard, D.O.2    Taylor, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.