Boron-lipiodol: A potential new drug for the treatment of liver tumors

Anticancer Research

Volumn 22, Issue 6 C, 2002, Pages 3989-3992

  Lin, Wan Yu ^a   Chi, Chin Wen ^b   Ho, Yung Jen ^c   Wu, I Chieh ^d   Chung, Yang Tsung ^d   Chen, San Duo ^d   Chou, Fong In ^e   Kai, Ji Jong ^e   Lui, Wing Yiu ^b   Chen, Te Jung ^f   Lin, Yungchang ^d  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^f INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

Author keywords

Boron lipiodol; Liver tumors

Indexed keywords

BORON LIPIODOL; IODINATED POPPYSEED OIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL EMBOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG UPTAKE; HEPATIC ARTERY; KIDNEY FUNCTION; LINEAR ENERGY TRANSFER; LIVER FUNCTION TEST; LIVER TUMOR; NEUTRON CAPTURE THERAPY; NEUTRON RADIATION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; BORON; BORON NEUTRON CAPTURE THERAPY; IODIZED OIL; KIDNEY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; RABBITS; TISSUE DISTRIBUTION;

EID: 0036875348     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Sauerwein W and Zurlo A: The EORTC Boron Neutron Capture Therapy (BNCT) Group. Achievements and future projects. Eur J Cancer 38: Suppl 4: 31-34, 2002.
2. Nakagawa Y and Hatanaka H: Boron neutron capture therapy clinical brain tumor studies. J Neuro-Oncol 33: 105-115, 1997.
3. Coderre JA, Elowitz EH, Chadha M, Bergland R, Capala J, Joel DD, Liu HyB, Slatkin DN and Chanana AD: Boron neutron capture therapy for glioblastoma multiforme using p-boronophenylalanine and epithermal neutrons trial design and early clinical results. J Neuro-Oncol 33: 141-152, 1997.
4. Dagrosa MA, Viaggi M, Kreimann E, Farias S, Garavaglia R, Agote M, Cabrini RL, Dadino JL, Juvenal GJ and Pisarev MA: Selective uptake of p-boronphenylalanine by undifferentiated thyroid carcinoma for boron neutron capture therapy. Thyroid 12: 7-12, 2002.
5. Kreimann EL, Itoiz ME, Dagrosa A, Garavaglia R, Farias S, Batistoni D and Schwint AE: The hamster cheek pouch as a model of oral cancer for boron neutron capture therapy studies: selective delivery of boron by boronophenylalanine. Cancer Res 61: 8775-8781, 2001.
6. Tjarks W, Barth R, Rotaru JH, Adams DM, Yang W, Kultyshev RG, Forrester J, Barnum BA, Soloway AH and Shore SG: In Vivo evaluation of phosphorous-containing derivatives of dodecahydrocloso-dodecaborate for boron neutron capture therapy of gliomas and sarcomas. Anticancer Res 21: 841-846, 2001.
7. Barth RF, Soloway AH, Goodman JH, Gahbauer RA, Gupta N, Blue TE, Yang W and Tjarks W: Boron neutron capture therapy of brain tumors: an emerging therapeutic modality. Neurosurgery 33: 433-451, 1999.
8. Nakakuma K, Tashiro S, Hiraoka K, Ogata K and Ootsuka K: Hepatocellular carcinoma and metastatic cancer detected by iodized oil. Radiology 154: 15-17, 1985.
9. Nye E, Butler P, Clingan PC and Morris DL: Lopiodol avid liven metastases from adenocortical carcinoma: Prospects for therapy? Anticancer Res 21: 1445-1448, 2001.
10. Yumoto Y, Jinno K, Tokuyama K, Araki Y, Ishimitsu T, Maeda H, Konno T, Iwamoto S, Ohnishi K and Okuda K: Hepatocellular carcinoma detected by iodized oil. Radiology 154: 19-24, 1985.
11. Kanematsu T, Inokuchi K, Sugimachi K, Furuta T, Sonoda T, Tamura S and Hasuo K: Selective effects of lipiodolized antitumor agents. J Surg Oncol 25: 218-226, 1984.
12. Oue T, Fukuzawa M, Kusafuka T, Kohmoto Y, Okada A and Imura K: Transcatheter arterial chemoembolization in the treatment of hepatoblastoma. J Pediatr Surg 33: 1771-1775, 1998.
13. Raoul JL, Duvauferrier R, Bourguet P, Bretagne JF, Coornaert S, Darnault P, Deugnier Y, Herry JY and Gastard J: Angiography with 1-131-iodine labeled iodized oil in malignant hepatoma, J Radiol 67: 797-801, 1986.
14. Wang SJ, Lin WY, Chen MN, Shen LH, Tsai ZC and Ting G: Preparation and biodistribution of Yttrium-90 lipiodol in rats following hepatic arterial injection. Eur J Nucl Med 22: 233-236, 1995.
15. Wang SJ, Lin WY, Hsih BT, Shen LH, Tsai ZC and Ting G: Biodistribution of Re-188 lipiodol infused via the hepatic artery of rats with hepatic tumor. Eur J Nucl Med 23: 13-17, 1996.
16. Wang SJ, Lin WY, Chen MN, Chi GS, Chen ZD, Ho L, Hsih BT, Shen LH, Tsai ZC, Ting G, Saed Mirzadeh, Furn F and Knapp Jr: Intratumoral injection of Rhenium-188 microsphere in animal model of hepatoma. J Nucl Med 39: 1752-1757, 1998.
17. Lin WY, Tsai SC, Hsieh JF and Wang SJ: Effects of Yttrium-90 microspheres on liver tumor: comparison of intra-tumoral injection method and intra-arterial injection method. J Nucl Med 41: 1892-1897, 2000.
18. Chou FI, Lui WY, Wei YY, Chung RJ, Kai JJ and Chi CW: Preparation and in vitro evaluation of B-lipiodol as a boron delivery agent for neutron capture therapy of hepatoma. Anticancer Res 19: 1759-1764, 1999.
19. Maki S, Konno T and Maeda H: Image enhancement in computerized tomography for sensitive diagnosis of liver cancer and semiquantitation of tumor selective drug targeting with oily contrast medium. Cancer 56: 751-757, 1985.
20. Yumoto Y, Jinno K, Tokuyama K, Araki Y, Ishimitsu T, Maeda H, Konno T, Iwamoto S, Ohnishi K and Okuda K: Hepatocellular carcinoma detected by iodized oil. Radiology 154: 19-24, 1985.
21. Akashi Y, Koreeda C, Mizuno T, Inoue K, Kawa SH and Tanaka Y: Hepatic parenchymal changes after the intraarterial injection of lipiodol in tumor-bearing rabbits. Invest Radiol 28: 128-132, 1993.
22. Ngan H: Lipiodol computerized tomography: how sensitive and specific is the technique in the diagnosis of hepatocellular carcinoma? Br J Radiol 63: 771-775, 1990.
23. Packer S, Coderre J, Saraf S, Fairchild R, Hansrote J and Perry H: Boron neutron capture therapy of anterior chamber melanoma with p-boronophenylalanine. Invest Ophthalmol Vis Sci 33: 395-403, 1992.
24. Konno T, Maeda H, Iwai K, Maki S, Tashiro S, Uchida M and Miyauchi Y: Selective targeting of anti-cancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium. Cancer 54: 2367-2374, 1984.
25. Saito Y, Sasaki T, Tarusawa K, Midorikawa H, Kanehira J, Ikami I, Yodono H and Takekawa SD: Chemoembolization therapy of hepatocellular carcinoma-antitumor effect and side effect. Gan To Kagaku Ryoho 15: 3283-3289, 1988.
26. Akashi Y, Koreeda C, Mizuno T, Inoue K, Kawa SH and Tanaka Y: Hepatic parenchymal changes after the intraarterial injection of lipiodol in tumor-bearing rabbits. Invest Radiol 28: 128-132, 1993.