In vivo evaluation of phosphorous-containing derivatives of dodecahydro-closo-dodecaborate for boron neutron capture therapy of gliomas and sarcomas

Anticancer Research

Volumn 21, Issue 2 A, 2001, Pages 841-846

  Tjarks, W ^a   Barth, R F ^a   Rotaru, J H ^a   Adams, D M ^a   Yang, W ^a   Kultyshev, R G ^a   Forrester, J ^a   Barnum, B A ^a   Soloway, A H ^a   Shore, S G ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Bisphosphonate; Boron neutron capture therapy; Dodecahydro closo dodecaborate; Phosphate

Indexed keywords

ANTINEOPLASTIC AGENT; DODECAHYDRO CLOSO DODECABORATE DERIVATIVE; PHOSPHORUS DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DOSE RESPONSE; DRUG POTENCY; GLIOMA; MOUSE; NEUTRON CAPTURE THERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOMA; TISSUE DISTRIBUTION; TOXICITY TESTING;

ANIMALS; BONE NEOPLASMS; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; DIPHOSPHONATES; GLIOMA; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; NEOPLASMS, EXPERIMENTAL; OSTEOSARCOMA; PHOSPHATES; PHOSPHORUS COMPOUNDS; RATS; RATS, INBRED F344; TECHNETIUM TC 99M MEDRONATE; TISSUE DISTRIBUTION; TUMOR CELLS, CULTURED;

EID: 0035021839     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Boron neutron capture therapy of brain tumors: An emerging therapy modality
2. The chemistry of neutron capture therapy
3. Boron neutron capture therapy of brain tumors: Enhanced survival and cure following blood-brain barrier disruption and intracarotid injection of sodium borocaptate and boronophenylalanine
4. Early history of development of boron neutron capture therapy of tumors
5. Synthesis and tumor-uptake study of phosphate esters of polyhedral hydroxyboranes
6. -
7. Toward a cancer therapy with boron-rich oligomeric phosphate diesters that target the cell nucleus
8. Alkyl carboranyl sulfonates as available synthons for carboranyl derivatives, especially for carborane-containing phosphonic acid esters
9. Interactions of carborane-containing electrophiles with triethyl phosphite. Synthesis of new carborane-containing phosphonates
10. Multiple extraosseous metastases from osteogenic sarcoma demonstrated on bone scintigraphy
11. 2_
12. Synthesis, characterization and animal testings of new boronated phosphonate and gem-bisphosphonate
13. Osteogenic potential of murine osteosarcoma cells: Comparison of bone-specific gene expression in in vitro and in vivo conditions
14. Determination of boron in tissues and cells using direct-current plasma atomic emission spectroscopy
15. Boron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption
16. Boron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of sodium borocaptate with or without blood-brain barrier disruption
17. Boron-10-mercaptoundecahydrododecaborate distribution in human brain tumors and quality control of boron compounds
18. Boron uptake by human brain tumors and quality, control of boron compounds
19. Developments in the therapeutic application of bisphosphonates
20. Treatment of metastatic disease in osteosarcoma patients. New applications of radiolabelled poly- and bis-phosphonates
21. 153Sm-EDTMP
22. 212Bi-EDTMP-synthesis and biodistribution of a novel bone seeking alpha-emitting radiopharmaceutical
23. 212Bi-DOTMP: An alpha particle emitting bone-seeking agent for targeted radiotherapy
24. 153 EDTMP
25. Tolerance of normal tissue to therapeutic irradiation
26. In vitro and in vivo evaluation of carboranyl uridines as boron delivery agents for neutron capture therapy