Extremely long recovery time for the sedative effect of clonidine in male type 1 alcohol-dependent subjects in full sustained remission

Alcohol

Volumn 28, Issue 3, 2002, Pages 181-187

  Berggren, Ulf ^a   Eriksson, Matts ^a   Fahlke, Claudia ^b   Sundkler, Anders ^a   Balldin, Jan ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Alcohol dependence; Alpha 2 adrenoceptors; Blood pressure; Clonidine sedation; Full sustained remission; Heart rate

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; SEDATIVE AGENT;

ADULT; AGED; ALCOHOLISM; ARTICLE; CORRELATION ANALYSIS; DIASTOLIC BLOOD PRESSURE; HEART RATE; HUMAN; MALE; REDUCTION; REMISSION; SCORING SYSTEM; SEDATION; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; ALCOHOLISM; BLOOD PRESSURE; CLONIDINE; HEART RATE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; TEMPERANCE;

EID: 0036873766     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(02)00276-8     Document Type: Article

References (17)

1. Alling C., Balldin J., Bokström K., Gottfries C.G., Karlsson I., Långström G. Studies on duration of a late recovery period after chronic abuse of ethanol. A cross-sectional study of biochemical and psychiatric indicators. Acta Psychiatr Scand. 66:1982;384-397.
2. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. 4th ed:1994;Author, Washington, DC.
3. Balldin J., Berggren U., Engel J., Lindstedt G., Sundkler A., Wålinder J. Alpha-2-adrenoceptor sensitivity in early alcohol withdrawal. Biol Psychiatr. 31:1992;712-719.
4. Berggren U., Fahlke C., Norrby A., Zachrisson O., Balldin J. Subsensitive alpha-2-adrenoceptor function in male alcohol-dependent individuals during 6 months of abstinence. Drug Alcohol Depend. 57:2000;255-260.
5. Fahlke C., Berggren U., Balldin J. Mental well-being in alcohol withdrawal. relationship to alpha2-adrenoreceptor function Alcohol Alcohol. 34:1999;718-725. a.
6. Fahlke C., Berggren U., Balldin J. Cardiovascular responses to clonidine in alcohol withdrawal. are they related to psychopathology and mental well-being? Alcohol. 21:2000;231-237.
7. Fahlke C., Berggren U., Lundborg C., Balldin J. Psychopathology in alcohol withdrawal. relationship to alpha2-adrenoreceptor function Alcohol Alcohol. 34:1999;750-759. b.
8. Glue P., Sellman J.D., Nicholls M.G., Abbott R., Joyce P.R., Nutt D.J. Studies of alpha-2-adrenoceptor function in abstinent alcoholics. Br J Addict. 84:1989;97-102.
9. Klimek V., Zhu M.Y., Dilley G., Konick L., Overholser J.C., Meltzer H.Y., May W.L., Stockmeier C.A., Ordway G.A. Effects of long-term cigarette smoking on the human locus coeruleus. Arch Gen Psychiatry. 58:2001;821-827.
10. Linnoila M., Mefford I., Nutt D., Adinoff B. Alcohol withdrawal and noradrenergic function. Ann Intern Med. 107:1987;875-889.
11. Maldonado R. Participation of noradrenergic pathways in the expression of opiate withdrawal. biochemical and pharmacological evidence Neurosci Biobehav Rev. 21:1997;91-104.
12. Matussek N., Ackenheil M., Herz M. The dependence of the clonidine growth hormone test on alcohol drinking habits and the menstrual cycle. Psychoneuroendocrinology. 9:1984;173-177.
13. Müller N., Hoehe M., Klein H.E., Nieberle G., Kapfhammer H.P., May F., Müller O.A., Fichter M. Endocrinological studies in alcoholics during withdrawal and after abstinence. Psychoneuroendocrinology. 14:1989;113-123.
14. Nutt D., Glue P., Molyneux S., Clark E. Alpha-2-adrenoceptor function in alcohol withdrawal. a pilot study of the effects of iv clonidine in alcoholics and normals Alcohol Clin Exp Res. 12:1988;14-18.
15. Szmigielski A., Szmigielski H., Wejman I. The effect of prolonged ethanol administration on central alpha 2-adrenoceptors sensitivity. Pol J Pharmacol Pharm. 41:1989;263-272.
16. Tulen J.H.M., van de Wetering B.J.M., Kruijk M.P.C.W., von Saher R.A., Moleman P., Boomsma F., van Steenis H.G., Man in 't Veld A.J. Cardiovascular, neuroendocrine, and sedative responses to four graded doses of clonidine in a placebo-controlled study. Biol Psychiatry. 32:1992;485-500.
17. Vaillant G.E. A long-term follow-up of male alcohol abuse. Arch Gen Psychiatry. 53:1996;243-249.