The effects of GABA and vigabatrin on horizontal cell responses to light and the effect of vigabatrin on the electroretinogram

Documenta Ophthalmologica

Volumn 105, Issue 3, 2002, Pages 313-326

  Hanitzsch, R ^a   Kuppers L ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Electroretinogram; GABA; Horizontal cells; M ller cells; Vigabatrin

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRATE AMINOTRANSFERASE INHIBITOR; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; ANTICONVULSIVE AGENT; ENZYME INHIBITOR; VIGABATRIN;

AMINO ACID BLOOD LEVEL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B WAVE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; DRUG UPTAKE; ELECTRORETINOGRAM; ENZYME INHIBITION; ISOLATED RETINA; LIGHT; LONG TERM CARE; MUELLER CELL; NERVE CELL; NONHUMAN; PHOTOREACTIVITY; RABBIT; RETINA; RETINA BIPOLAR GANGLION CELL; RETINA HORIZONTAL NERVE CELL; STATISTICAL SIGNIFICANCE; VISUAL FIELD; VISUAL IMPAIRMENT;

ANIMALS; ANTICONVULSANTS; ELECTRORETINOGRAPHY; GAMMA-AMINOBUTYRIC ACID; LIGHT; NEURONS; PHOTIC STIMULATION; RABBITS; RETINA; VIGABATRIN;

EID: 0036865868     PISSN: 00124486     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021270201902     Document Type: Article

References (33)

1. Eke T, Talbot JF, Lawden MC. Severe persistent visual field constriction associated with vigabatrin. Br Med J 1997; 314: 180-1.
2. Harding GF, Wild JM, Robertson KA, Rietbrock S, Martinez C. Separating the retinal electrophysiologic effects of vigabatrin treatment versus field loss. Am J Ophthalmol 2000; 130: 691.
3. Harding GF, Wild JM, Robertson KA, Lawden MC, Betts, TA, Barber C, Barnes PM. Electro-oculography, electroretinography, visual evoked potentials, and multifocal electroretinography in patients with vigabatrin-attributed visual field constriction. Epilepsia 2000; 41: 1420-31.
4. Pow DV, Baldridge W, Crook DK. Activity-dependent transport of GABA analogues into specific cell types demonstrated at high resolution using a novel immunocytochemical strategy. Neuroscience 1996; 73: 1129-43.
5. Johnson J, Chen TK, Rickman DW, Evans C, Brecha NC. Multiple γ-aminobutyric acid plasma membrane transporters (GAT-1, GAT-2, GAT-3) in the rat retina. J Comp Neurol 1996; 375: 212-4.
6. Neal MJ, Cunningham JR, Shah MA, Yazulla S. Immunocytochemical evidence that vigabatrin in rats causes GABA accumulation in glial cells of the retina. Neurosci Lett 1989; 98: 29-32.
7. Gurevich L, Slaughter MM. Comparison of the waveform of the ON bipolar neuron and the b-wave of the electroretinogram. Vision Res 1993; 33: 2431-5.
8. Xu X, Karwoski C. Current source density (CSD) analysis of retinal field potentials. I. Methodological considerations and depth profiles. J Neurophysiol 1994; 72: 84-95.
9. Xu X, Karwoski C. Current source density analysis of retinal field potentials. II. Pharmacological analysis of the b-wave and M-wave. J Neurophysiol 1994; 72: 96-102.
10. Sieving PA, Murayama K, Naarendorp F. Push-pull model of the primate photopic electroretinogram: A role for hyperpolarizing neurons in shaping the b-wave. Vis Neurosci 1994; 11: 519-32.
11. 2 and APB on the light-induced potassium changes and the ERG b-wave of the isolated superfused rat retina. Vision Res 1996; 36: 499-507.
12. Wurziger K, Lichtenberger T, Hanitzsch R. On-bipolar cells and amacrine cells as the origin of the ERG-b-wave in the RCS rat. Vision Res 2001; 41, 1091-101.
13. Hanitzsch R. Intraretinal isolation of PIII-subcomponents in the isolated rabbit retina after treatment with sodium aspartate. Vision Res 1973; 13: 2093-102.
14. Tomita T. Electrophysiological studies of retinal cell function. Invest Ophthalmol 1976; 15: 169-87.
15. Steinberg RH, Frishman LJ, Sieving PA. Negative components of the electroretinogram from proximal retina and photoreceptor. Prog Retinal Res 1991; 10: 121-60.
16. Hanitzsch R. A comparison between the slow cornea-negative PIII-component of the ERG and potassium changes in the isolated rabbit retina. Doc Ophthalmol 1993; 84: 267-78.
17. Hanitzsch R, Bornschein H. Spezielle Überlebensbedingungen für isolierte Netzhäute verschiedener Warmblüter. Experientia 1965; 21: 484.
18. Hanitzsch R, Tomita, T, Wagner H. A chamber preserving cellular function of the isolated rabbit retina suited for extracellular and intracellular recording. Ophthalmic Res 1984; 16: 27-30.
19. Hanitzsch R, Küppers L. The influence of HEPES on light responses of rabbit horizontal cells. Vision Res 2001; 41: 2165-72.
20. Johnson MA, Krauss GL, Miller NR, Medura M, Paul SR. Visual function loss from vigabatrin. Effect of stopping the drug. Am J Ophthalmol 2000; 130: 691.
21. Rüther K, Pung T, Kellner U, Schmitz B, Hartmann C, Seeliger M. Electrophysiologic evaluation of a patient with peripheral visual field contractions associated with vigabatrin. Arch Ophthalmol 1998; 6: 817-9.
22. Neal MJ, Shah MA. Development of tolerance to the effects of vigabatrin (γ-vinyl-GABA) on GABA release from rat cerebral cortex, spinal cord and retina. Br J Pharmacol 1990; 100: 324-28.
23. A agonists. Vis Neurosci 1995; 12: 651-61.
24. A antagonists. Vis Neurosci 1995; 12: 641-50.
25. A receptors in the rabbit retina. Cell Tiss Res 1994; 276: 295-307.
26. Wässle H, Koulen P, Brandstätter JH, Fletcher EL, Becker CM. Glycine and GABA receptors in the mammalian retina. Vision Res 1998; 38: 1411-30.
27. Vardi N, Kaufman DL, Sterling P. Horizontal cells in cat and monkey retina express different isoforms of glutamic acid decarboxylase. Vis Neurosci 1994; 11: 135-42.
28. Blanco R, Vaquero CF, De La Villa P. The effects of GABA and glycine on horizontal cells of the rabbit retina. Vision Res 1996; 36: 3987-96.
29. Sills GJ, Patsalos PN, Butler E, Forrest G, Ratnaraj N, Brodie MJ. Visual field constriction: Accumulation of vigabatrin but not tiagabine in the retina. Neurology 2001; 57: 196-200.
30. Gottlob I, Wündsch L, Tuppy FK. The rabbit electroretinogram: Effect of GABA and its antagonists. Vision Res 1988; 28: 203-10.
31. Pow DV. Differences in cellular sites of accumulation of vigabatrin in central versus peripheral primate retina. International Society for Clinical Electrophysiology of Vision. 38th Symposium, Sydney, Australia, 2000.
32. Reichenbach A, Robinson SR. Phylogenetic constraints on retinal organization and development. Prog Retin Eye Res 1995; 15, 139-71.
33. Wachtmeister L. Oscillatory potentials in the retina: What do they reveal. Prog Retin Eye Res 1998; 485-521.