Time to take epigenetic inheritance seriously

European Journal of Human Genetics

Volumn 10, Issue 11, 2002, Pages 669-671

  Pembrey, Marcus E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ancestors' nutrition; BORIS; Diabetes; Epigenetic inheritance; Imprinting

Indexed keywords

ARTICLE; CARDIOVASCULAR DISEASE; FAMILY; FOOD AVAILABILITY; GENE EXPRESSION; GENETIC SELECTION; GENOME IMPRINTING; GROWTH PERIOD; HUMAN; INFANT MORTALITY; INHERITANCE; LIFESPAN; LONGEVITY; METABOLISM; MORTALITY; NUTRITION; PARENT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SPERMATOCYTE; SPERMATOGENESIS; SURVIVAL; SWEDEN; VARIABLE NUMBER OF TANDEM REPEAT; VERTICAL TRANSMISSION; DIABETES MELLITUS; DIET; EVOLUTION; GENETICS; NOTE;

CTCFL PROTEIN, HUMAN; DNA BINDING PROTEIN;

DIABETES MELLITUS; DIET; DNA-BINDING PROTEINS; EVOLUTION; GENOMIC IMPRINTING; HUMANS; SELECTION (GENETICS);

EID: 0036861531     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200901     Document Type: Article

References (18)

1. Kaati G, Bygren LD, Edvinsson S: Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. Eur J Hum Genet 2002; 10: 682-688.
2. Bygren LO, Kaati G, Edvinsson S: Longevity determined by ancestors' overnutrition during their slow growth period. Acta Biotheoretica 2001; 49: 53-59.
3. Campbell JH, Perkins P: Transgenerational effects of drug and hormone treatments in mammals: a review of observations and ideas. Prog Brain Res 1988; 73: 535-553.
4. Boucher BJ, Ewen SW, Stowers JM: Betel nut (Areca catechu) consumption and the induction of glucose intolerance in adult CD1 mice and in their F1 and F2 offspring. Diabetologia 1994; 37: 49-55.
5. Roemer I, Reik W, Dean W et al: Epigenetic inheritance of specific changes in gene expression in the mouse. Curr Biol 1997; 7: 277-280.
6. Morgan HD, Sutherland HG, Martin DI et al: Epigenetic inheritance at the agouti locus in the mouse. Nat Genet 1999; 23: 314-318.
7. Wolff GL, Kodell RL, Moore SR et al: Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice. FASEB J 1998; 12: 949-957.
8. Beaudet AL, Jiang Y: A rheostat model for a rapid and reversible form of imprinting-dependent evolution. Am J Hum Genet 2002; 70: 1389-1397.
9. Pembrey M: Imprinting and transgenerational modulation of gene expression; human growth as a model. Acta Genet Med Gemellol (Roma) 1996; 45: 111-125.
10. Judson H, Hayward BE, Sheridan E et al: A global disorder of imprinting in the human female germ line. Nature 2002; 416: 539-542.
11. Bennett ST, Wilson AJ, Esposito L et al: Insulin VNTR allele-specific effect in type 1 diabetes depends on the identity of untransmitted paternal allele. Nat Genet 1997; 17: 350-352.
12. Ong KK, Phillips DI, Fall C et al: The insulin gene VNTR, type 2 diabetes and birth weight. Nat Genet 1999; 21: 262-263.
13. Loukinov DI, Pugacheva E, Vatolin S et al: BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. PNAS 2002; 99: 6806-6811.
14. Klenova EM, Morse III HC, Ohlsson R, Lobanenkov VV: The novel BORIS+CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Seminars in Cancer Biology 2002; 12: 399-414.
15. Ohlsson R, Renkawitz R, Lobanenkov V: CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet 2001; 17: 520-527.
16. Muller J, Skakkebaek NE: Quantification of germ cells and semini-ferous tubules by stereological examination of the testicles from 50 boys who suffered from sudden death. Int J Androl 1983; 6: 143-156.
17. Nistal M, Paniagua R: Occurrence of primary spermatocytes in the infant and child testis. Andrologia 1984; 16: 532-536.
18. Trainer TD: Histology of the normal testis. Am J Surg Pathol 1987; 11: 797-809.