Reaction safety: A critical parameter in the development of a scaleable synthesis of 2,3-bis-chloromethylpyridine hydrochloride

Organic Process Research and Development

Volumn 6, Issue 6, 2002, Pages 938-942

  Grimm, J S ^a   Maryanoff, C A ^a   Patel, M ^a   Palmer, D C ^a   Sorgi, K L ^a   Stefanick, S ^a   Webster, R R H ^a   Zhang, X ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 BIS(CHLOROMETHYLPYRIDINE); CHLORIDE; PICOLINE DERIVATIVE; TOLUENE; UNCLASSIFIED DRUG;

CALORIMETRY; CHLORINATION; CONFERENCE PAPER; DECOMPOSITION; HAZARD ASSESSMENT; SAFETY; SCALE UP; SYNTHESIS;

EID: 0036857597     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op025545n     Document Type: Conference Paper

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